380 related articles for article (PubMed ID: 32023055)
1. Designing Chimeric Molecules for Drug Discovery by Leveraging Chemical Biology.
Borsari C; Trader DJ; Tait A; Costi MP
J Med Chem; 2020 Mar; 63(5):1908-1928. PubMed ID: 32023055
[TBL] [Abstract][Full Text] [Related]
2. Replicated, replicable and relevant-target engagement and pharmacological experimentation in the 21st century.
Kenakin T; Bylund DB; Toews ML; Mullane K; Winquist RJ; Williams M
Biochem Pharmacol; 2014 Jan; 87(1):64-77. PubMed ID: 24269285
[TBL] [Abstract][Full Text] [Related]
3. Formulation and Delivery of Macromolecules.
Morales JO
AAPS PharmSciTech; 2017 Jan; 18(1):1-2. PubMed ID: 27943123
[No Abstract] [Full Text] [Related]
4. A network view of disease and compound screening.
Schadt EE; Friend SH; Shaywitz DA
Nat Rev Drug Discov; 2009 Apr; 8(4):286-95. PubMed ID: 19337271
[TBL] [Abstract][Full Text] [Related]
5. Chemistry-enabled drug delivery (prodrugs): recent progress and challenges.
Clas SD; Sanchez RI; Nofsinger R
Drug Discov Today; 2014 Jan; 19(1):79-87. PubMed ID: 23993918
[TBL] [Abstract][Full Text] [Related]
6. Pharmacokinetics and the drug-target residence time concept.
Dahl G; Akerud T
Drug Discov Today; 2013 Aug; 18(15-16):697-707. PubMed ID: 23500610
[TBL] [Abstract][Full Text] [Related]
7. Design and pharmaceutical applications of proteolysis-targeting chimeric molecules.
Liang Y; Nandakumar KS; Cheng K
Biochem Pharmacol; 2020 Dec; 182():114211. PubMed ID: 32866456
[TBL] [Abstract][Full Text] [Related]
8. Drug-therapy networks and the prediction of novel drug targets.
Spiro Z; Kovacs IA; Csermely P
J Biol; 2008 Jul; 7(6):20. PubMed ID: 18710588
[TBL] [Abstract][Full Text] [Related]
9. Directing evolution: the next revolution in drug discovery?
Davis AM; Plowright AT; Valeur E
Nat Rev Drug Discov; 2017 Oct; 16(10):681-698. PubMed ID: 28935911
[TBL] [Abstract][Full Text] [Related]
10. Taking a systems approach to the identification of novel therapeutic targets and biomarkers.
Dunn DA; Apanovitch D; Follettie M; He T; Ryan T
Curr Pharm Biotechnol; 2010 Nov; 11(7):721-34. PubMed ID: 20809898
[TBL] [Abstract][Full Text] [Related]
11. Extending the small-molecule similarity principle to all levels of biology with the Chemical Checker.
Duran-Frigola M; Pauls E; Guitart-Pla O; Bertoni M; Alcalde V; Amat D; Juan-Blanco T; Aloy P
Nat Biotechnol; 2020 Sep; 38(9):1087-1096. PubMed ID: 32440005
[TBL] [Abstract][Full Text] [Related]
12. Chimeric mice with humanized liver: Application in drug metabolism and pharmacokinetics studies for drug discovery.
Naritomi Y; Sanoh S; Ohta S
Drug Metab Pharmacokinet; 2018 Feb; 33(1):31-39. PubMed ID: 29183653
[TBL] [Abstract][Full Text] [Related]
13. Recent advances in biological strategies for targeted drug delivery.
Ye X; Yang D
Cardiovasc Hematol Disord Drug Targets; 2009 Sep; 9(3):206-21. PubMed ID: 19817715
[TBL] [Abstract][Full Text] [Related]
14. Oral druggable space beyond the rule of 5: insights from drugs and clinical candidates.
Doak BC; Over B; Giordanetto F; Kihlberg J
Chem Biol; 2014 Sep; 21(9):1115-42. PubMed ID: 25237858
[TBL] [Abstract][Full Text] [Related]
15. Multidimensional targeting: using physical and chemical forces in unison.
Van Lehn RC; Sing CE; Chen H; Alexander-Katz A
Curr Pharm Biotechnol; 2010 Jun; 11(4):320-32. PubMed ID: 20201796
[TBL] [Abstract][Full Text] [Related]
16. Application of chemical biology in target identification and drug discovery.
Zhu Y; Xiao T; Lei S; Zhou F; Wang MW
Arch Pharm Res; 2015 Sep; 38(9):1642-50. PubMed ID: 26242900
[TBL] [Abstract][Full Text] [Related]
17. Exploring Chemical and Biological Space of Terpenoids.
Zeng T; Liu Z; Liu H; He W; Tang X; Xie L; Wu R
J Chem Inf Model; 2019 Sep; 59(9):3667-3678. PubMed ID: 31403297
[TBL] [Abstract][Full Text] [Related]
18. Approaches to target profiling of natural products.
Yue R; Shan L; Yang X; Zhang W
Curr Med Chem; 2012; 19(22):3841-55. PubMed ID: 22257052
[TBL] [Abstract][Full Text] [Related]
19. Defining and characterizing drug/compound function.
Kenakin T; Williams M
Biochem Pharmacol; 2014 Jan; 87(1):40-63. PubMed ID: 23954707
[TBL] [Abstract][Full Text] [Related]
20. Target engagement in lead generation.
Durham TB; Blanco MJ
Bioorg Med Chem Lett; 2015 Mar; 25(5):998-1008. PubMed ID: 25630223
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
