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4. FYN expression potentiates FLT3-ITD induced STAT5 signaling in acute myeloid leukemia. Chougule RA; Kazi JU; Rönnstrand L Oncotarget; 2016 Mar; 7(9):9964-74. PubMed ID: 26848862 [TBL] [Abstract][Full Text] [Related]
5. The FLT3-ITD mutation and the expression of its downstream signaling intermediates STAT5 and Pim-1 are positively correlated with CXCR4 expression in patients with acute myeloid leukemia. Cao T; Jiang N; Liao H; Shuai X; Su J; Zheng Q Sci Rep; 2019 Aug; 9(1):12209. PubMed ID: 31434952 [TBL] [Abstract][Full Text] [Related]
6. FLT3-ITD confers resistance to the PI3K/Akt pathway inhibitors by protecting the mTOR/4EBP1/Mcl-1 pathway through STAT5 activation in acute myeloid leukemia. Nogami A; Oshikawa G; Okada K; Fukutake S; Umezawa Y; Nagao T; Kurosu T; Miura O Oncotarget; 2015 Apr; 6(11):9189-205. PubMed ID: 25826077 [TBL] [Abstract][Full Text] [Related]
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9. FLT3-ITD up-regulates MCL-1 to promote survival of stem cells in acute myeloid leukemia via FLT3-ITD-specific STAT5 activation. Yoshimoto G; Miyamoto T; Jabbarzadeh-Tabrizi S; Iino T; Rocnik JL; Kikushige Y; Mori Y; Shima T; Iwasaki H; Takenaka K; Nagafuji K; Mizuno S; Niiro H; Gilliland GD; Akashi K Blood; 2009 Dec; 114(24):5034-43. PubMed ID: 19808698 [TBL] [Abstract][Full Text] [Related]
10. FLT3-ITD transduces autonomous growth signals during its biosynthetic trafficking in acute myelogenous leukemia cells. Yamawaki K; Shiina I; Murata T; Tateyama S; Maekawa Y; Niwa M; Shimonaka M; Okamoto K; Suzuki T; Nishida T; Abe R; Obata Y Sci Rep; 2021 Nov; 11(1):22678. PubMed ID: 34811450 [TBL] [Abstract][Full Text] [Related]
12. The protein tyrosine phosphatase, Shp2, positively contributes to FLT3-ITD-induced hematopoietic progenitor hyperproliferation and malignant disease in vivo. Nabinger SC; Li XJ; Ramdas B; He Y; Zhang X; Zeng L; Richine B; Bowling JD; Fukuda S; Goenka S; Liu Z; Feng GS; Yu M; Sandusky GE; Boswell HS; Zhang ZY; Kapur R; Chan RJ Leukemia; 2013 Feb; 27(2):398-408. PubMed ID: 23103841 [TBL] [Abstract][Full Text] [Related]
13. Internal tandem duplication of FLT3 deregulates proliferation and differentiation and confers resistance to the FLT3 inhibitor AC220 by Up-regulating RUNX1 expression in hematopoietic cells. Hirade T; Abe M; Onishi C; Taketani T; Yamaguchi S; Fukuda S Int J Hematol; 2016 Jan; 103(1):95-106. PubMed ID: 26590920 [TBL] [Abstract][Full Text] [Related]
14. Roles of tyrosine 589 and 591 in STAT5 activation and transformation mediated by FLT3-ITD. Rocnik JL; Okabe R; Yu JC; Lee BH; Giese N; Schenkein DP; Gilliland DG Blood; 2006 Aug; 108(4):1339-45. PubMed ID: 16627759 [TBL] [Abstract][Full Text] [Related]
15. Constitutive activation of Flt3 and STAT5A enhances self-renewal and alters differentiation of hematopoietic stem cells. Moore MA; Dorn DC; Schuringa JJ; Chung KY; Morrone G Exp Hematol; 2007 Apr; 35(4 Suppl 1):105-16. PubMed ID: 17379095 [TBL] [Abstract][Full Text] [Related]
16. Breakdown of the FLT3-ITD/STAT5 axis and synergistic apoptosis induction by the histone deacetylase inhibitor panobinostat and FLT3-specific inhibitors. Pietschmann K; Bolck HA; Buchwald M; Spielberg S; Polzer H; Spiekermann K; Bug G; Heinzel T; Böhmer FD; Krämer OH Mol Cancer Ther; 2012 Nov; 11(11):2373-83. PubMed ID: 22942377 [TBL] [Abstract][Full Text] [Related]
19. FLT3-ITD expression levels and their effect on STAT5 in AML with and without NPM mutations. Seedhouse CH; Pallis M; Grundy M; Shang S; Russell NH Br J Haematol; 2009 Dec; 147(5):653-61. PubMed ID: 19775300 [TBL] [Abstract][Full Text] [Related]
20. FLT3-ITD and TLR9 use Bruton tyrosine kinase to activate distinct transcriptional programs mediating AML cell survival and proliferation. Oellerich T; Mohr S; Corso J; Beck J; Döbele C; Braun H; Cremer A; Münch S; Wicht J; Oellerich MF; Bug G; Bohnenberger H; Perske C; Schütz E; Urlaub H; Serve H Blood; 2015 Mar; 125(12):1936-47. PubMed ID: 25605370 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]