250 related articles for article (PubMed ID: 32027820)
1. The Plasma Membrane as a Competitive Inhibitor and Positive Allosteric Modulator of KRas4B Signaling.
Neale C; García AE
Biophys J; 2020 Mar; 118(5):1129-1141. PubMed ID: 32027820
[TBL] [Abstract][Full Text] [Related]
2. Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site.
Mazhab-Jafari MT; Marshall CB; Smith MJ; Gasmi-Seabrook GM; Stathopulos PB; Inagaki F; Kay LE; Neel BG; Ikura M
Proc Natl Acad Sci U S A; 2015 May; 112(21):6625-30. PubMed ID: 25941399
[TBL] [Abstract][Full Text] [Related]
3. PIP2 Influences the Conformational Dynamics of Membrane-Bound KRAS4b.
McLean MA; Stephen AG; Sligar SG
Biochemistry; 2019 Aug; 58(33):3537-3545. PubMed ID: 31339036
[TBL] [Abstract][Full Text] [Related]
4. Allosteric KRas4B Can Modulate SOS1 Fast and Slow Ras Activation Cycles.
Liao TJ; Jang H; Fushman D; Nussinov R
Biophys J; 2018 Aug; 115(4):629-641. PubMed ID: 30097175
[TBL] [Abstract][Full Text] [Related]
5. Membrane Composition and Raf[CRD]-Membrane Attachment Are Driving Forces for K-Ras4B Dimer Stability.
Andreadelis I; Kiriakidi S; Lamprakis C; Theodoropoulou A; Doerr S; Chatzigoulas A; Manchester J; Velez-Vega C; Duca JS; Cournia Z
J Phys Chem B; 2022 Feb; 126(7):1504-1519. PubMed ID: 35142524
[TBL] [Abstract][Full Text] [Related]
6. Methionine 170 is an Environmentally Sensitive Membrane Anchor in the Disordered HVR of K-Ras4B.
Neale C; García AE
J Phys Chem B; 2018 Nov; 122(44):10086-10096. PubMed ID: 30351122
[TBL] [Abstract][Full Text] [Related]
7. Oncogenic K-Ras Binds to an Anionic Membrane in Two Distinct Orientations: A Molecular Dynamics Analysis.
Prakash P; Zhou Y; Liang H; Hancock JF; Gorfe AA
Biophys J; 2016 Mar; 110(5):1125-38. PubMed ID: 26958889
[TBL] [Abstract][Full Text] [Related]
8. Membrane-bound KRAS approximates an entropic ensemble of configurations.
Heinrich F; Van QN; Jean-Francois F; Stephen AG; Lösche M
Biophys J; 2021 Sep; 120(18):4055-4066. PubMed ID: 34384763
[TBL] [Abstract][Full Text] [Related]
9. GTP-Bound N-Ras Conformational States and Substates Are Modulated by Membrane and Point Mutation.
Farcas A; Janosi L
Int J Mol Sci; 2024 Jan; 25(3):. PubMed ID: 38338709
[TBL] [Abstract][Full Text] [Related]
10. Conserved allosteric perturbation of the GTPase domains by region 1 of Ras hypervariable regions.
Gu X; Zhang Y; Long D
Biophys J; 2024 Apr; 123(7):839-846. PubMed ID: 38419331
[TBL] [Abstract][Full Text] [Related]
11. K-Ras G-domain binding with signaling lipid phosphatidylinositol (4,5)-phosphate (PIP2): membrane association, protein orientation, and function.
Cao S; Chung S; Kim S; Li Z; Manor D; Buck M
J Biol Chem; 2019 Apr; 294(17):7068-7084. PubMed ID: 30792310
[TBL] [Abstract][Full Text] [Related]
12. Direct Modulators of K-Ras-Membrane Interactions.
Morstein J; Shrestha R; Van QN; López CA; Arora N; Tonelli M; Liang H; Chen D; Zhou Y; Hancock JF; Stephen AG; Turbyville TJ; Shokat KM
ACS Chem Biol; 2023 Sep; 18(9):2082-2093. PubMed ID: 37579045
[TBL] [Abstract][Full Text] [Related]
13. Arl2-Mediated Allosteric Release of Farnesylated KRas4B from Shuttling Factor PDEδ.
Ozdemir ES; Jang H; Gursoy A; Keskin O; Nussinov R
J Phys Chem B; 2018 Aug; 122(30):7503-7513. PubMed ID: 29961325
[TBL] [Abstract][Full Text] [Related]
14. Membrane interactions of the globular domain and the hypervariable region of KRAS4b define its unique diffusion behavior.
Goswami D; Chen D; Yang Y; Gudla PR; Columbus J; Worthy K; Rigby M; Wheeler M; Mukhopadhyay S; Powell K; Burgan W; Wall V; Esposito D; Simanshu DK; Lightstone FC; Nissley DV; McCormick F; Turbyville T
Elife; 2020 Jan; 9():. PubMed ID: 31958057
[TBL] [Abstract][Full Text] [Related]
15. Insight into the mechanism of allosteric activation of PI3Kα by oncoprotein K-Ras4B.
Li X; Dai J; Ni D; He X; Zhang H; Zhang J; Fu Q; Liu Y; Lu S
Int J Biol Macromol; 2020 Feb; 144():643-655. PubMed ID: 31816384
[TBL] [Abstract][Full Text] [Related]
16. Probing the Conformational and Energy Landscapes of KRAS Membrane Orientation.
Prakash P; Gorfe AA
J Phys Chem B; 2019 Oct; 123(41):8644-8652. PubMed ID: 31554397
[TBL] [Abstract][Full Text] [Related]
17. How Anionic Lipids Affect Spatiotemporal Properties of KRAS4B on Model Membranes.
Ngo VA; Sarkar S; Neale C; Garcia AE
J Phys Chem B; 2020 Jul; 124(26):5434-5453. PubMed ID: 32438809
[TBL] [Abstract][Full Text] [Related]
18. Computational Design of Myristoylated Cell-Penetrating Peptides Targeting Oncogenic K-Ras.G12D at the Effector-Binding Membrane Interface.
Li Z; Buck M
J Chem Inf Model; 2020 Jan; 60(1):306-315. PubMed ID: 31855604
[TBL] [Abstract][Full Text] [Related]
19. Lipid-Sorting Specificity Encoded in K-Ras Membrane Anchor Regulates Signal Output.
Zhou Y; Prakash P; Liang H; Cho KJ; Gorfe AA; Hancock JF
Cell; 2017 Jan; 168(1-2):239-251.e16. PubMed ID: 28041850
[TBL] [Abstract][Full Text] [Related]
20. Is Nanoclustering essential for all oncogenic KRas pathways? Can it explain why wild-type KRas can inhibit its oncogenic variant?
Nussinov R; Tsai CJ; Jang H
Semin Cancer Biol; 2019 Feb; 54():114-120. PubMed ID: 29307569
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]