BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

330 related articles for article (PubMed ID: 32029588)

  • 1. Lack of RAN-mediated toxicity in Huntington's disease knock-in mice.
    Yang S; Yang H; Huang L; Chen L; Qin Z; Li S; Li XJ
    Proc Natl Acad Sci U S A; 2020 Feb; 117(8):4411-4417. PubMed ID: 32029588
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A CAG repeat threshold for therapeutics targeting somatic instability in Huntington's disease.
    Aldous SG; Smith EJ; Landles C; Osborne GF; Cañibano-Pico M; Nita IM; Phillips J; Zhang Y; Jin B; Hirst MB; Benn CL; Bond BC; Edelmann W; Greene JR; Bates GP
    Brain; 2024 May; 147(5):1784-1798. PubMed ID: 38387080
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PolyQ-independent toxicity associated with novel translational products from CAG repeat expansions.
    Rudich P; Watkins S; Lamitina T
    PLoS One; 2020; 15(4):e0227464. PubMed ID: 32240172
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice.
    Gu X; Richman J; Langfelder P; Wang N; Zhang S; Bañez-Coronel M; Wang HB; Yang L; Ramanathan L; Deng L; Park CS; Choi CR; Cantle JP; Gao F; Gray M; Coppola G; Bates GP; Ranum LPW; Horvath S; Colwell CS; Yang XW
    Neuron; 2022 Apr; 110(7):1173-1192.e7. PubMed ID: 35114102
    [TBL] [Abstract][Full Text] [Related]  

  • 5. CAG RNAs induce DNA damage and apoptosis by silencing
    Peng S; Guo P; Lin X; An Y; Sze KH; Lau MHY; Chen ZS; Wang Q; Li W; Sun JK; Ma SY; Chan TF; Lau KF; Ngo JCK; Kwan KM; Wong CH; Lam SL; Zimmerman SC; Tuccinardi T; Zuo Z; Au-Yeung HY; Chow HM; Chan HYE
    Proc Natl Acad Sci U S A; 2021 May; 118(19):. PubMed ID: 33947817
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Genetic Contributors to Intergenerational CAG Repeat Instability in Huntington's Disease Knock-In Mice.
    Neto JL; Lee JM; Afridi A; Gillis T; Guide JR; Dempsey S; Lager B; Alonso I; Wheeler VC; Pinto RM
    Genetics; 2017 Feb; 205(2):503-516. PubMed ID: 27913616
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington's disease knock-in mice is blocked by Mlh1 knock-out.
    Loupe JM; Pinto RM; Kim KH; Gillis T; Mysore JS; Andrew MA; Kovalenko M; Murtha R; Seong I; Gusella JF; Kwak S; Howland D; Lee R; Lee JM; Wheeler VC; MacDonald ME
    Hum Mol Genet; 2020 Nov; 29(18):3044-3053. PubMed ID: 32876667
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Gelation of cytoplasmic expanded CAG RNA repeats suppresses global protein synthesis.
    Pan Y; Lu J; Feng X; Lu S; Yang Y; Yang G; Tan S; Wang L; Li P; Luo S; Lu B
    Nat Chem Biol; 2023 Nov; 19(11):1372-1383. PubMed ID: 37592155
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Expanded CAG repeats in the murine Huntington's disease gene increases neuronal differentiation of embryonic and neural stem cells.
    Lorincz MT; Zawistowski VA
    Mol Cell Neurosci; 2009 Jan; 40(1):1-13. PubMed ID: 18625318
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Longitudinal behavioral, cross-sectional transcriptional and histopathological characterization of a knock-in mouse model of Huntington's disease with 140 CAG repeats.
    Rising AC; Xu J; Carlson A; Napoli VV; Denovan-Wright EM; Mandel RJ
    Exp Neurol; 2011 Apr; 228(2):173-82. PubMed ID: 21192926
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RNA toxicity induced by expanded CAG repeats in Huntington's disease.
    Martí E
    Brain Pathol; 2016 Nov; 26(6):779-786. PubMed ID: 27529325
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Potential Transfer of Polyglutamine and CAG-Repeat RNA in Extracellular Vesicles in Huntington's Disease: Background and Evaluation in Cell Culture.
    Zhang X; Abels ER; Redzic JS; Margulis J; Finkbeiner S; Breakefield XO
    Cell Mol Neurobiol; 2016 Apr; 36(3):459-70. PubMed ID: 26951563
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels.
    Rué L; Bañez-Coronel M; Creus-Muncunill J; Giralt A; Alcalá-Vida R; Mentxaka G; Kagerbauer B; Zomeño-Abellán MT; Aranda Z; Venturi V; Pérez-Navarro E; Estivill X; Martí E
    J Clin Invest; 2016 Nov; 126(11):4319-4330. PubMed ID: 27721240
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Lack of huntingtin promotes neural stem cells differentiation into glial cells while neurons expressing huntingtin with expanded polyglutamine tracts undergo cell death.
    Conforti P; Camnasio S; Mutti C; Valenza M; Thompson M; Fossale E; Zeitlin S; MacDonald ME; Zuccato C; Cattaneo E
    Neurobiol Dis; 2013 Feb; 50():160-70. PubMed ID: 23089356
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Introducing an Expanded Trinucleotide Repeat Tract into the Human Genome for Huntington's Disease Modeling In Vitro.
    Malankhanova T; Sorokin M; Medvedev S; Zakian S; Malakhova A
    Curr Protoc Hum Genet; 2020 Jun; 106(1):e100. PubMed ID: 32469433
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Repeat-associated non-AUG translation induces cytoplasmic aggregation of CAG repeat-containing RNAs.
    Das MR; Chang Y; Anderson R; Saunders RA; Zhang N; Tomberlin CP; Vale RD; Jain A
    Proc Natl Acad Sci U S A; 2023 Jan; 120(3):e2215071120. PubMed ID: 36623192
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Age-dependent and tissue-specific CAG repeat instability occurs in mouse knock-in for a mutant Huntington's disease gene.
    Ishiguro H; Yamada K; Sawada H; Nishii K; Ichino N; Sawada M; Kurosawa Y; Matsushita N; Kobayashi K; Goto J; Hashida H; Masuda N; Kanazawa I; Nagatsu T
    J Neurosci Res; 2001 Aug; 65(4):289-97. PubMed ID: 11494364
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RAN Translation of the Expanded CAG Repeats in the SCA3 Disease Context.
    Jazurek-Ciesiolka M; Ciesiolka A; Komur AA; Urbanek-Trzeciak MO; Krzyzosiak WJ; Fiszer A
    J Mol Biol; 2020 Dec; 432(24):166699. PubMed ID: 33157084
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Quantification of age-dependent somatic CAG repeat instability in Hdh CAG knock-in mice reveals different expansion dynamics in striatum and liver.
    Lee JM; Pinto RM; Gillis T; St Claire JC; Wheeler VC
    PLoS One; 2011; 6(8):e23647. PubMed ID: 21897851
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phenotype onset in Huntington's disease knock-in mice is correlated with the incomplete splicing of the mutant huntingtin gene.
    Franich NR; Hickey MA; Zhu C; Osborne GF; Ali N; Chu T; Bove NH; Lemesre V; Lerner RP; Zeitlin SO; Howland D; Neueder A; Landles C; Bates GP; Chesselet MF
    J Neurosci Res; 2019 Dec; 97(12):1590-1605. PubMed ID: 31282030
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.