112 related articles for article (PubMed ID: 3203411)
1. Covalent binding of acetaminophen to mouse hemoglobin. Identification of major and minor adducts formed in vivo and implications for the nature of the arylating metabolites.
Axworthy DB; Hoffmann KJ; Streeter AJ; Calleman CJ; Pascoe GA; Baillie TA
Chem Biol Interact; 1988; 68(1-2):99-116. PubMed ID: 3203411
[TBL] [Abstract][Full Text] [Related]
2. Identification of the major covalent adduct formed in vitro and in vivo between acetaminophen and mouse liver proteins.
Hoffmann KJ; Streeter AJ; Axworthy DB; Baillie TA
Mol Pharmacol; 1985 May; 27(5):566-73. PubMed ID: 3990678
[TBL] [Abstract][Full Text] [Related]
3. Immunochemical analysis of acetaminophen covalent binding to proteins. Partial characterization of the major acetaminophen-binding liver proteins.
Bartolone JB; Birge RB; Sparks K; Cohen SD; Khairallah EA
Biochem Pharmacol; 1988 Dec; 37(24):4763-74. PubMed ID: 3060126
[TBL] [Abstract][Full Text] [Related]
4. Inactivation of glyceraldehyde-3-phosphate dehydrogenase by a reactive metabolite of acetaminophen and mass spectral characterization of an arylated active site peptide.
Dietze EC; Schäfer A; Omichinski JG; Nelson SD
Chem Res Toxicol; 1997 Oct; 10(10):1097-103. PubMed ID: 9348431
[TBL] [Abstract][Full Text] [Related]
5. The covalent binding of acetaminophen to protein. Evidence for cysteine residues as major sites of arylation in vitro.
Streeter AJ; Dahlin DC; Nelson SD; Baillie TA
Chem Biol Interact; 1984 Mar; 48(3):349-66. PubMed ID: 6713598
[TBL] [Abstract][Full Text] [Related]
6. Comparison of covalent binding of acetaminophen and the regioisomer 3'-hydroxyacetanilide to mouse liver protein.
Matthews AM; Hinson JA; Roberts DW; Pumford NR
Toxicol Lett; 1997 Jan; 90(1):77-82. PubMed ID: 9020405
[TBL] [Abstract][Full Text] [Related]
7. Identification of S-(2,5-dihydroxyphenyl)-cysteine and S-(2,5-dihydroxyphenyl)-N-acetyl-cysteine as urinary metabolites of acetaminophen in the mouse. Evidence for p-benzoquinone as a reactive intermediate in acetaminophen metabolism.
Pascoe GA; Calleman CJ; Baille TA
Chem Biol Interact; 1988; 68(1-2):85-98. PubMed ID: 3203410
[TBL] [Abstract][Full Text] [Related]
8. Acetaminophen-induced hepatotoxicity. Analysis of total covalent binding vs. specific binding to cysteine.
Matthews AM; Roberts DW; Hinson JA; Pumford NR
Drug Metab Dispos; 1996 Nov; 24(11):1192-6. PubMed ID: 8937852
[TBL] [Abstract][Full Text] [Related]
9. Role of CYP1A2 in the hepatotoxicity of acetaminophen: investigations using Cyp1a2 null mice.
Tonge RP; Kelly EJ; Bruschi SA; Kalhorn T; Eaton DL; Nebert DW; Nelson SD
Toxicol Appl Pharmacol; 1998 Nov; 153(1):102-8. PubMed ID: 9875304
[TBL] [Abstract][Full Text] [Related]
10. Acetaminophen nephrotoxicity in the rat: quantitation of renal metabolic activation in vivo.
Newton JF; Pasino DA; Hook JB
Toxicol Appl Pharmacol; 1985 Mar; 78(1):39-46. PubMed ID: 4035671
[TBL] [Abstract][Full Text] [Related]
11. Acetaminophen binds to mouse hepatic and renal DNA at human therapeutic doses.
Rogers LK; Moorthy B; Smith CV
Chem Res Toxicol; 1997 Apr; 10(4):470-6. PubMed ID: 9114986
[TBL] [Abstract][Full Text] [Related]
12. Repeat exposure to incremental doses of acetaminophen provides protection against acetaminophen-induced lethality in mice: an explanation for high acetaminophen dosage in humans without hepatic injury.
Shayiq RM; Roberts DW; Rothstein K; Snawder JE; Benson W; Ma X; Black M
Hepatology; 1999 Feb; 29(2):451-63. PubMed ID: 9918922
[TBL] [Abstract][Full Text] [Related]
13. Hepatic protein arylation, glutathione depletion, and metabolite profiles of acetaminophen and a non-hepatotoxic regioisomer, 3'-hydroxyacetanilide, in the mouse.
Rashed MS; Myers TG; Nelson SD
Drug Metab Dispos; 1990; 18(5):765-70. PubMed ID: 1981734
[TBL] [Abstract][Full Text] [Related]
14. Selective protein arylation by acetaminophen and 2,6-dimethylacetaminophen in cultured hepatocytes from phenobarbital-induced and uninduced mice. Relationship to cytotoxicity.
Birge RB; Bartolone JB; McCann DJ; Mangold JB; Cohen SD; Khairallah EA
Biochem Pharmacol; 1989 Dec; 38(24):4429-38. PubMed ID: 2604745
[TBL] [Abstract][Full Text] [Related]
15. Immunoblot analysis of protein containing 3-(cystein-S-yl)acetaminophen adducts in serum and subcellular liver fractions from acetaminophen-treated mice.
Pumford NR; Hinson JA; Benson RW; Roberts DW
Toxicol Appl Pharmacol; 1990 Jul; 104(3):521-32. PubMed ID: 2385841
[TBL] [Abstract][Full Text] [Related]
16. Acetaminophen nephrotoxicity in the rat. Renal metabolic activation in vitro.
Newton JF; Bailie MB; Hook JB
Toxicol Appl Pharmacol; 1983 Sep; 70(3):433-44. PubMed ID: 6636173
[TBL] [Abstract][Full Text] [Related]
17. Role of NAD(P)H:quinone oxidoreductase 1 in clofibrate-mediated hepatoprotection from acetaminophen.
Moffit JS; Aleksunes LM; Kardas MJ; Slitt AL; Klaassen CD; Manautou JE
Toxicology; 2007 Feb; 230(2-3):197-206. PubMed ID: 17188792
[TBL] [Abstract][Full Text] [Related]
18. Acetaminophen structure-toxicity studies: in vivo covalent binding of a nonhepatotoxic analog, 3-hydroxyacetanilide.
Roberts SA; Price VF; Jollow DJ
Toxicol Appl Pharmacol; 1990 Sep; 105(2):195-208. PubMed ID: 2219115
[TBL] [Abstract][Full Text] [Related]
19. In vivo covalent binding of [14C]trinitrotoluene to proteins in the rat.
Liu YY; Lu AY; Stearns RA; Chiu SH
Chem Biol Interact; 1992 Mar; 82(1):1-19. PubMed ID: 1547511
[TBL] [Abstract][Full Text] [Related]
20. Selective acetaminophen metabolite binding to hepatic and extrahepatic proteins: an in vivo and in vitro analysis.
Bartolone JB; Beierschmitt WP; Birge RB; Hart SG; Wyand S; Cohen SD; Khairallah EA
Toxicol Appl Pharmacol; 1989 Jun; 99(2):240-9. PubMed ID: 2734789
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
