BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 32035298)

  • 1. Enhanced antitumor potential induced by chloroacetate-loaded benzophenones acting as fused tubulin-pyruvate dehydrogenase kinase 1 (PDHK1) ligands.
    Ghinet A; Thuru X; Floquet E; Dubois J; Farce A; Rigo B
    Bioorg Chem; 2020 Mar; 96():103643. PubMed ID: 32035298
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents.
    Penthala NR; Zong H; Ketkar A; Madadi NR; Janganati V; Eoff RL; Guzman ML; Crooks PA
    Eur J Med Chem; 2015 Mar; 92():212-20. PubMed ID: 25557492
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 2-amino-3,4,5-trimethoxybenzophenones as potent tubulin polymerization inhibitors.
    Chuang HY; Chang JY; Lai MJ; Kuo CC; Lee HY; Hsieh HP; Chen YJ; Chen LT; Pan WY; Liou JP
    ChemMedChem; 2011 Mar; 6(3):450-6. PubMed ID: 21360819
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and biological evaluation of novel benzo[c]acridine-diones as potential anticancer agents and tubulin polymerization inhibitors.
    Behbahani FS; Tabeshpour J; Mirzaei S; Golmakaniyoon S; Tayarani-Najaran Z; Ghasemi A; Ghodsi R
    Arch Pharm (Weinheim); 2019 Jun; 352(6):e1800307. PubMed ID: 31012156
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Indolizine-phenothiazine hybrids as the first dual inhibitors of tubulin polymerization and farnesyltransferase with synergistic antitumor activity.
    Moise IM; Bîcu E; Farce A; Dubois J; Ghinet A
    Bioorg Chem; 2020 Oct; 103():104184. PubMed ID: 32891861
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Platinum(IV) complexes conjugated with phenstatin analogue as inhibitors of microtubule polymerization and reverser of multidrug resistance.
    Huang X; Huang R; Gou S; Wang Z; Liao Z; Wang H
    Bioorg Med Chem; 2017 Sep; 25(17):4686-4700. PubMed ID: 28728896
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis, biological evaluation, and molecular docking analysis of phenstatin based indole linked chalcones as anticancer agents and tubulin polymerization inhibitors.
    Kode J; Kovvuri J; Nagaraju B; Jadhav S; Barkume M; Sen S; Kasinathan NK; Chaudhari P; Mohanty BS; Gour J; Sigalapalli DK; Ganesh Kumar C; Pradhan T; Banerjee M; Kamal A
    Bioorg Chem; 2020 Dec; 105():104447. PubMed ID: 33207276
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antitumor Activity of Asperphenin A, a Lipopeptidyl Benzophenone from Marine-Derived
    Bae SY; Liao L; Park SH; Kim WK; Shin J; Lee SK
    Mar Drugs; 2020 Feb; 18(2):. PubMed ID: 32069904
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, biological evaluation, and 3D-QSAR analysis of podophyllotoxin-dioxazole combination as tubulin targeting anticancer agents.
    Wang ZZ; Sun WX; Wang X; Zhang YH; Qiu HY; Qi JL; Pang YJ; Lu GH; Wang XM; Yu FG; Yang YH
    Chem Biol Drug Des; 2017 Aug; 90(2):236-243. PubMed ID: 28079286
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis, anti-cancer evaluation of benzenesulfonamide derivatives as potent tubulin-targeting agents.
    Yang J; Yang S; Zhou S; Lu D; Ji L; Li Z; Yu S; Meng X
    Eur J Med Chem; 2016 Oct; 122():488-496. PubMed ID: 27423028
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, Synthesis and Cancer Cell Growth Inhibition Evaluation of New Aminoquinone Hybrid Molecules.
    Defant A; Mancini I
    Molecules; 2019 Jun; 24(12):. PubMed ID: 31197105
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and biological evaluation of cinnamido linked benzophenone hybrids as tubulin polymerization inhibitors and apoptosis inducing agents.
    Kamal A; Reddy ChR; Vishnuvardhan MV; Mahesh R; Lakshma Nayak V; Prabhakar S; Reddy CS
    Bioorg Med Chem Lett; 2014 May; 24(10):2309-14. PubMed ID: 24736114
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of CKD-516: a potent tubulin polymerization inhibitor with marked antitumor activity against murine and human solid tumors.
    Lee J; Kim SJ; Choi H; Kim YH; Lim IT; Yang HM; Lee CS; Kang HR; Ahn SK; Moon SK; Kim DH; Lee S; Choi NS; Lee KJ
    J Med Chem; 2010 Sep; 53(17):6337-54. PubMed ID: 20690624
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of novel indole-pyrimidine hybrids bearing morpholine and thiomorpholine moieties.
    Diao PC; Li Q; Hu MJ; Ma YF; You WW; Hong KH; Zhao PL
    Eur J Med Chem; 2017 Jul; 134():110-118. PubMed ID: 28410492
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and evaluation of new 2-chloro-4-aminopyrimidine and 2,6-dimethyl-4-aminopyrimidine derivatives as tubulin polymerization inhibitors.
    Xu S; An B; Li Y; Luo X; Li X; Jia X
    Bioorg Med Chem Lett; 2018 Jun; 28(10):1769-1775. PubMed ID: 29673981
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development of potent dual PDK1/AurA kinase inhibitors for cancer therapy: Lead-optimization, structural insights, and ADME-Tox profile.
    Sestito S; Bacci A; Chiarugi S; Runfola M; Gado F; Margheritis E; Gul S; Riveiro ME; Vazquez R; Huguet S; Manera C; Rezai K; Garau G; Rapposelli S
    Eur J Med Chem; 2021 Dec; 226():113895. PubMed ID: 34624821
    [TBL] [Abstract][Full Text] [Related]  

  • 17. (E)-N-Aryl-2-oxo-2-(3,4,5-trimethoxyphenyl)acetohydrazonoyl cyanides as tubulin polymerization inhibitors: Structure-based bioisosterism design, synthesis, biological evaluation, molecular docking and in silico ADME prediction.
    Wang G; Peng Z; Peng S; Qiu J; Li Y; Lan Y
    Bioorg Med Chem Lett; 2018 Nov; 28(20):3350-3355. PubMed ID: 30197030
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, antiproliferative, anti-tubulin activity, and docking study of new 1,2,4-triazoles as potential combretastatin analogues.
    Mustafa M; Abdelhamid D; Abdelhafez EMN; Ibrahim MAA; Gamal-Eldeen AM; Aly OM
    Eur J Med Chem; 2017 Dec; 141():293-305. PubMed ID: 29031074
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological evaluation of podophyllotoxin congeners as tubulin polymerization inhibitors.
    Kamal A; Srinivasa Reddy T; Polepalli S; Shalini N; Reddy VG; Subba Rao AV; Jain N; Shankaraiah N
    Bioorg Med Chem; 2014 Oct; 22(19):5466-75. PubMed ID: 25131956
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, biological evaluation and molecular docking of benzimidazole grafted benzsulfamide-containing pyrazole ring derivatives as novel tubulin polymerization inhibitors.
    Wang YT; Shi TQ; Zhu HL; Liu CH
    Bioorg Med Chem; 2019 Feb; 27(3):502-515. PubMed ID: 30606674
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.