398 related articles for article (PubMed ID: 32036254)
1. Proof of site-specificity of antibody-drug conjugates produced by chemical conjugation technology: AJICAP first generation.
Matsuda Y; Malinao MC; Robles V; Song J; Yamada K; Mendelsohn BA
J Chromatogr B Analyt Technol Biomed Life Sci; 2020 Mar; 1140():121981. PubMed ID: 32036254
[TBL] [Abstract][Full Text] [Related]
2. Comparison of Analytical Methods for Antibody-Drug Conjugates Produced by Chemical Site-Specific Conjugation: First-Generation AJICAP.
Matsuda Y; Robles V; Malinao MC; Song J; Mendelsohn BA
Anal Chem; 2019 Oct; 91(20):12724-12732. PubMed ID: 31478640
[TBL] [Abstract][Full Text] [Related]
3. Chemical Site-Specific Conjugation Platform to Improve the Pharmacokinetics and Therapeutic Index of Antibody-Drug Conjugates.
Matsuda Y; Seki T; Yamada K; Ooba Y; Takahashi K; Fujii T; Kawaguchi S; Narita T; Nakayama A; Kitahara Y; Mendelsohn BA; Okuzumi T
Mol Pharm; 2021 Nov; 18(11):4058-4066. PubMed ID: 34579528
[TBL] [Abstract][Full Text] [Related]
4. A Purification Strategy Utilizing Hydrophobic Interaction Chromatography to Obtain Homogeneous Species from a Site-Specific Antibody Drug Conjugate Produced by AJICAP™ First Generation.
Matsuda Y; Leung M; Okuzumi T; Mendelsohn B
Antibodies (Basel); 2020 May; 9(2):. PubMed ID: 32443479
[TBL] [Abstract][Full Text] [Related]
5. Characterization of Ring-Opening Reaction of Succinimide Linkers in ADCs.
Zheng K; Chen Y; Wang J; Zheng L; Hutchinson M; Persson J; Ji J
J Pharm Sci; 2019 Jan; 108(1):133-141. PubMed ID: 30458165
[TBL] [Abstract][Full Text] [Related]
6. Recent Chemical Approaches for Site-Specific Conjugation of Native Antibodies: Technologies toward Next-Generation Antibody-Drug Conjugates.
Yamada K; Ito Y
Chembiochem; 2019 Nov; 20(21):2729-2737. PubMed ID: 30973187
[TBL] [Abstract][Full Text] [Related]
7. AJICAP Second Generation: Improved Chemical Site-Specific Conjugation Technology for Antibody-Drug Conjugate Production.
Fujii T; Matsuda Y; Seki T; Shikida N; Iwai Y; Ooba Y; Takahashi K; Isokawa M; Kawaguchi S; Hatada N; Watanabe T; Takasugi R; Nakayama A; Shimbo K; Mendelsohn BA; Okuzumi T; Yamada K
Bioconjug Chem; 2023 Mar; 34(4):728-38. PubMed ID: 36894324
[TBL] [Abstract][Full Text] [Related]
8. Chromatographic analysis of site-specific antibody-drug conjugates produced by AJICAP first-generation technology using a recombinant FcγIIIa receptor-ligand affinity column.
Matsuda Y; Chakrabarti A; Takahashi K; Yamada K; Nakata K; Okuzumi T; Mendelsohn BA
J Chromatogr B Analyt Technol Biomed Life Sci; 2021 Jul; 1177():122753. PubMed ID: 34098178
[TBL] [Abstract][Full Text] [Related]
9. Biological Evaluation of Maytansinoid-Based Site-Specific Antibody-Drug Conjugate Produced by Fully Chemical Conjugation Approach: AJICAP®.
Seki T; Yamada K; Ooba Y; Fujii T; Narita T; Nakayama A; Kitahara Y; Mendelsohn BA; Matsuda Y; Okuzumi T
Front Biosci (Landmark Ed); 2022 Aug; 27(8):234. PubMed ID: 36042175
[TBL] [Abstract][Full Text] [Related]
10. Antibody-Drug Conjugates (ADCs) Derived from Interchain Cysteine Cross-Linking Demonstrate Improved Homogeneity and Other Pharmacological Properties over Conventional Heterogeneous ADCs.
Behrens CR; Ha EH; Chinn LL; Bowers S; Probst G; Fitch-Bruhns M; Monteon J; Valdiosera A; Bermudez A; Liao-Chan S; Wong T; Melnick J; Theunissen JW; Flory MR; Houser D; Venstrom K; Levashova Z; Sauer P; Migone TS; van der Horst EH; Halcomb RL; Jackson DY
Mol Pharm; 2015 Nov; 12(11):3986-98. PubMed ID: 26393951
[TBL] [Abstract][Full Text] [Related]
11. AJICAP: Affinity Peptide Mediated Regiodivergent Functionalization of Native Antibodies.
Yamada K; Shikida N; Shimbo K; Ito Y; Khedri Z; Matsuda Y; Mendelsohn BA
Angew Chem Int Ed Engl; 2019 Apr; 58(17):5592-5597. PubMed ID: 30854738
[TBL] [Abstract][Full Text] [Related]
12. Sortase Enzyme-Mediated Generation of Site-Specifically Conjugated Antibody Drug Conjugates with High In Vitro and In Vivo Potency.
Beerli RR; Hell T; Merkel AS; Grawunder U
PLoS One; 2015; 10(7):e0131177. PubMed ID: 26132162
[TBL] [Abstract][Full Text] [Related]
13. Conjugation Site Analysis of Lysine-Conjugated ADCs.
Sang H; Wan N; Lu G; Tian Y; Wang G; Ye H
Methods Mol Biol; 2020; 2078():235-250. PubMed ID: 31643061
[TBL] [Abstract][Full Text] [Related]
14. In vitro and in vivo evaluation of cysteine and site specific conjugated herceptin antibody-drug conjugates.
Jackson D; Atkinson J; Guevara CI; Zhang C; Kery V; Moon SJ; Virata C; Yang P; Lowe C; Pinkstaff J; Cho H; Knudsen N; Manibusan A; Tian F; Sun Y; Lu Y; Sellers A; Jia XC; Joseph I; Anand B; Morrison K; Pereira DS; Stover D
PLoS One; 2014; 9(1):e83865. PubMed ID: 24454709
[TBL] [Abstract][Full Text] [Related]
15. Characterization of cysteine-linked conjugation profiles of immunoglobulin G1 and immunoglobulin G2 antibody-drug conjugates.
Wiggins B; Liu-Shin L; Yamaguchi H; Ratnaswamy G
J Pharm Sci; 2015 Apr; 104(4):1362-72. PubMed ID: 25631158
[TBL] [Abstract][Full Text] [Related]
16. Conjugation site analysis of antibody-drug-conjugates (ADCs) by signature ion fingerprinting and normalized area quantitation approach using nano-liquid chromatography coupled to high resolution mass spectrometry.
Sang H; Lu G; Liu Y; Hu Q; Xing W; Cui D; Zhou F; Zhang J; Hao H; Wang G; Ye H
Anal Chim Acta; 2017 Feb; 955():67-78. PubMed ID: 28088282
[TBL] [Abstract][Full Text] [Related]
17. A Case Study to Identify the Drug Conjugation Site of a Site-Specific Antibody-Drug-Conjugate Using Middle-Down Mass Spectrometry.
Hernandez-Alba O; Houel S; Hessmann S; Erb S; Rabuka D; Huguet R; Josephs J; Beck A; Drake PM; Cianférani S
J Am Soc Mass Spectrom; 2019 Nov; 30(11):2419-2429. PubMed ID: 31429052
[TBL] [Abstract][Full Text] [Related]
18. Dual intra- and extracellular release of monomethyl auristatin E from a neutrophil elastase-sensitive antibody-drug conjugate.
Mohamed Amar IA; Huvelle S; Douez E; Letast S; Henrion S; Viaud-Massuard MC; Aubrey N; Allard-Vannier E; Joubert N; Denevault-Sabourin C
Eur J Med Chem; 2022 Feb; 229():114063. PubMed ID: 34974337
[TBL] [Abstract][Full Text] [Related]
19. Design and Validation of Linkers for Site-Specific Preparation of Antibody-Drug Conjugates Carrying Multiple Drug Copies Per Cysteine Conjugation Site.
Kumar A; Mao S; Dimasi N; Gao C
Int J Mol Sci; 2020 Sep; 21(18):. PubMed ID: 32961794
[TBL] [Abstract][Full Text] [Related]
20. A Novel Platinum(II)-Based Bifunctional ADC Linker Benchmarked Using 89Zr-Desferal and Auristatin F-Conjugated Trastuzumab.
Sijbrandi NJ; Merkul E; Muns JA; Waalboer DC; Adamzek K; Bolijn M; Montserrat V; Somsen GW; Haselberg R; Steverink PJ; Houthoff HJ; van Dongen GA
Cancer Res; 2017 Jan; 77(2):257-267. PubMed ID: 27872093
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
