These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. Evolution of Novel 3D Culture Systems for Studies of Human Liver Function and Assessments of the Hepatotoxicity of Drugs and Drug Candidates. Andersson TB Basic Clin Pharmacol Toxicol; 2017 Oct; 121(4):234-238. PubMed ID: 28470941 [TBL] [Abstract][Full Text] [Related]
6. Prediction of Drug-Induced Hepatotoxicity Using Long-Term Stable Primary Hepatic 3D Spheroid Cultures in Chemically Defined Conditions. Vorrink SU; Zhou Y; Ingelman-Sundberg M; Lauschke VM Toxicol Sci; 2018 Jun; 163(2):655-665. PubMed ID: 29590495 [TBL] [Abstract][Full Text] [Related]
7. Three-dimensional coculture of primary hepatocytes and stellate cells in silk scaffold improves hepatic morphology and functionality in vitro. Wei G; Wang J; Lv Q; Liu M; Xu H; Zhang H; Jin L; Yu J; Wang X J Biomed Mater Res A; 2018 Aug; 106(8):2171-2180. PubMed ID: 29607608 [TBL] [Abstract][Full Text] [Related]
8. Integrated in vitro models for hepatic safety and metabolism: evaluation of a human Liver-Chip and liver spheroid. Foster AJ; Chouhan B; Regan SL; Rollison H; Amberntsson S; Andersson LC; Srivastava A; Darnell M; Cairns J; Lazic SE; Jang KJ; Petropolis DB; Kodella K; Rubins JE; Williams D; Hamilton GA; Ewart L; Morgan P Arch Toxicol; 2019 Apr; 93(4):1021-1037. PubMed ID: 30915487 [TBL] [Abstract][Full Text] [Related]
9. Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study. Bell CC; Dankers ACA; Lauschke VM; Sison-Young R; Jenkins R; Rowe C; Goldring CE; Park K; Regan SL; Walker T; Schofield C; Baze A; Foster AJ; Williams DP; van de Ven AWM; Jacobs F; Houdt JV; Lähteenmäki T; Snoeys J; Juhila S; Richert L; Ingelman-Sundberg M Toxicol Sci; 2018 Apr; 162(2):655-666. PubMed ID: 29329425 [TBL] [Abstract][Full Text] [Related]
10. Metabolic Oscillations in Co-Cultures of Hepatocytes and Mesenchymal Stem Cells: Effects of Seeding Arrangement and Culture Mixing. Alzebdeh DA; Matthew HW J Cell Biochem; 2017 Sep; 118(9):3003-3015. PubMed ID: 28252220 [TBL] [Abstract][Full Text] [Related]
11. Cytotoxicity evaluation using cryopreserved primary human hepatocytes in various culture formats. Richert L; Baze A; Parmentier C; Gerets HHJ; Sison-Young R; Dorau M; Lovatt C; Czich A; Goldring C; Park BK; Juhila S; Foster AJ; Williams DP Toxicol Lett; 2016 Sep; 258():207-215. PubMed ID: 27363785 [TBL] [Abstract][Full Text] [Related]
12. Sensitivities of gel entrapped hepatocytes in hollow fibers to hepatotoxic drug. Meng Q; Zhang G; Shen C; Qiu H Toxicol Lett; 2006 Sep; 166(1):19-26. PubMed ID: 16814964 [TBL] [Abstract][Full Text] [Related]
13. Generation of hepatic spheroids using human hepatocyte-derived liver progenitor-like cells for hepatotoxicity screening. Wang Z; Li W; Jing H; Ding M; Fu G; Yuan T; Huang W; Dai M; Tang D; Zeng M; Chen Y; Zhang H; Zhu X; Peng Y; Li Q; Yu WF; Yan HX; Zhai B Theranostics; 2019; 9(22):6690-6705. PubMed ID: 31588244 [No Abstract] [Full Text] [Related]
14. A long-term three dimensional liver co-culture system for improved prediction of clinically relevant drug-induced hepatotoxicity. Kostadinova R; Boess F; Applegate D; Suter L; Weiser T; Singer T; Naughton B; Roth A Toxicol Appl Pharmacol; 2013 Apr; 268(1):1-16. PubMed ID: 23352505 [TBL] [Abstract][Full Text] [Related]
15. Transcriptional, Functional, and Mechanistic Comparisons of Stem Cell-Derived Hepatocytes, HepaRG Cells, and Three-Dimensional Human Hepatocyte Spheroids as Predictive In Vitro Systems for Drug-Induced Liver Injury. Bell CC; Lauschke VM; Vorrink SU; Palmgren H; Duffin R; Andersson TB; Ingelman-Sundberg M Drug Metab Dispos; 2017 Apr; 45(4):419-429. PubMed ID: 28137721 [TBL] [Abstract][Full Text] [Related]
16. Accessing 3D microtissue metabolism: Lactate and oxygen monitoring in hepatocyte spheroids. Weltin A; Hammer S; Noor F; Kaminski Y; Kieninger J; Urban GA Biosens Bioelectron; 2017 Jan; 87():941-948. PubMed ID: 27665516 [TBL] [Abstract][Full Text] [Related]
17. Fish hepatocyte spheroids - A powerful (though underexplored) alternative in vitro model to study hepatotoxicity. Alves RF; Rocha E; Madureira TV Comp Biochem Physiol C Toxicol Pharmacol; 2022 Dec; 262():109470. PubMed ID: 36122680 [TBL] [Abstract][Full Text] [Related]
18. Suspension culture of hepatocyte-derived reporter cells in presence of albumin to form stable three-dimensional spheroids. Weeks CA; Newman K; Turner PA; Rodysill B; Hickey RD; Nyberg SL; Janorkar AV Biotechnol Bioeng; 2013 Sep; 110(9):2548-55. PubMed ID: 23483526 [TBL] [Abstract][Full Text] [Related]
19. Bioprinted 3D Primary Liver Tissues Allow Assessment of Organ-Level Response to Clinical Drug Induced Toxicity In Vitro. Nguyen DG; Funk J; Robbins JB; Crogan-Grundy C; Presnell SC; Singer T; Roth AB PLoS One; 2016; 11(7):e0158674. PubMed ID: 27387377 [TBL] [Abstract][Full Text] [Related]
20. Current limitations and future opportunities for prediction of DILI from in vitro. Funk C; Roth A Arch Toxicol; 2017 Jan; 91(1):131-142. PubMed ID: 27766365 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]