371 related articles for article (PubMed ID: 32060489)
21. Lack of association of somatic CAG repeat expansion with striatal neurodegeneration in HD knock-in animal models.
Bai D; Yin P; Zhang Y; Sun F; Chen L; Lin L; Yan S; Li S; Li XJ
Hum Mol Genet; 2021 Jul; 30(16):1497-1508. PubMed ID: 33949657
[TBL] [Abstract][Full Text] [Related]
22. Mismatch repair genes Mlh1 and Mlh3 modify CAG instability in Huntington's disease mice: genome-wide and candidate approaches.
Pinto RM; Dragileva E; Kirby A; Lloret A; Lopez E; St Claire J; Panigrahi GB; Hou C; Holloway K; Gillis T; Guide JR; Cohen PE; Li GM; Pearson CE; Daly MJ; Wheeler VC
PLoS Genet; 2013 Oct; 9(10):e1003930. PubMed ID: 24204323
[TBL] [Abstract][Full Text] [Related]
23. Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington's disease.
O'Reilly D; Belgrad J; Ferguson C; Summers A; Sapp E; McHugh C; Mathews E; Boudi A; Buchwald J; Ly S; Moreno D; Furgal R; Luu E; Kennedy Z; Hariharan V; Monopoli K; Yang XW; Carroll J; DiFiglia M; Aronin N; Khvorova A
Mol Ther; 2023 Jun; 31(6):1661-1674. PubMed ID: 37177784
[TBL] [Abstract][Full Text] [Related]
24. Partial resistance to malonate-induced striatal cell death in transgenic mouse models of Huntington's disease is dependent on age and CAG repeat length.
Hansson O; Castilho RF; Korhonen L; Lindholm D; Bates GP; Brundin P
J Neurochem; 2001 Aug; 78(4):694-703. PubMed ID: 11520890
[TBL] [Abstract][Full Text] [Related]
25. Age-, tissue- and length-dependent bidirectional somatic CAG•CTG repeat instability in an allelic series of R6/2 Huntington disease mice.
Larson E; Fyfe I; Morton AJ; Monckton DG
Neurobiol Dis; 2015 Apr; 76():98-111. PubMed ID: 25662336
[TBL] [Abstract][Full Text] [Related]
26. Isolated short CTG/CAG DNA slip-outs are repaired efficiently by hMutSbeta, but clustered slip-outs are poorly repaired.
Panigrahi GB; Slean MM; Simard JP; Gileadi O; Pearson CE
Proc Natl Acad Sci U S A; 2010 Jul; 107(28):12593-8. PubMed ID: 20571119
[TBL] [Abstract][Full Text] [Related]
27. Age-dependent and tissue-specific CAG repeat instability occurs in mouse knock-in for a mutant Huntington's disease gene.
Ishiguro H; Yamada K; Sawada H; Nishii K; Ichino N; Sawada M; Kurosawa Y; Matsushita N; Kobayashi K; Goto J; Hashida H; Masuda N; Kanazawa I; Nagatsu T
J Neurosci Res; 2001 Aug; 65(4):289-97. PubMed ID: 11494364
[TBL] [Abstract][Full Text] [Related]
28. Modifiers of Somatic Repeat Instability in Mouse Models of Friedreich Ataxia and the Fragile X-Related Disorders: Implications for the Mechanism of Somatic Expansion in Huntington's Disease.
Zhao X; Kumari D; Miller CJ; Kim GY; Hayward B; Vitalo AG; Pinto RM; Usdin K
J Huntingtons Dis; 2021; 10(1):149-163. PubMed ID: 33579860
[TBL] [Abstract][Full Text] [Related]
29. A critical window of CAG repeat-length correlates with phenotype severity in the R6/2 mouse model of Huntington's disease.
Cummings DM; Alaghband Y; Hickey MA; Joshi PR; Hong SC; Zhu C; Ando TK; André VM; Cepeda C; Watson JB; Levine MS
J Neurophysiol; 2012 Jan; 107(2):677-91. PubMed ID: 22072510
[TBL] [Abstract][Full Text] [Related]
30. Expression levels of DNA replication and repair genes predict regional somatic repeat instability in the brain but are not altered by polyglutamine disease protein expression or age.
Mason AG; Tomé S; Simard JP; Libby RT; Bammler TK; Beyer RP; Morton AJ; Pearson CE; La Spada AR
Hum Mol Genet; 2014 Mar; 23(6):1606-18. PubMed ID: 24191263
[TBL] [Abstract][Full Text] [Related]
31. A selective inhibitor of histone deacetylase 3 prevents cognitive deficits and suppresses striatal CAG repeat expansions in Huntington's disease mice.
Suelves N; Kirkham-McCarthy L; Lahue RS; Ginés S
Sci Rep; 2017 Jul; 7(1):6082. PubMed ID: 28729730
[TBL] [Abstract][Full Text] [Related]
32. High resolution time-course mapping of early transcriptomic, molecular and cellular phenotypes in Huntington's disease CAG knock-in mice across multiple genetic backgrounds.
Ament SA; Pearl JR; Grindeland A; St Claire J; Earls JC; Kovalenko M; Gillis T; Mysore J; Gusella JF; Lee JM; Kwak S; Howland D; Lee MY; Baxter D; Scherler K; Wang K; Geman D; Carroll JB; MacDonald ME; Carlson G; Wheeler VC; Price ND; Hood LE
Hum Mol Genet; 2017 Mar; 26(5):913-922. PubMed ID: 28334820
[TBL] [Abstract][Full Text] [Related]
33. Base editing strategies to convert CAG to CAA diminish the disease-causing mutation in Huntington's disease.
Choi DE; Shin JW; Zeng S; Hong EP; Jang JH; Loupe JM; Wheeler VC; Stutzman HE; Kleinstiver B; Lee JM
Elife; 2024 Jun; 12():. PubMed ID: 38869243
[TBL] [Abstract][Full Text] [Related]
34. Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice.
Gu X; Richman J; Langfelder P; Wang N; Zhang S; Bañez-Coronel M; Wang HB; Yang L; Ramanathan L; Deng L; Park CS; Choi CR; Cantle JP; Gao F; Gray M; Coppola G; Bates GP; Ranum LPW; Horvath S; Colwell CS; Yang XW
Neuron; 2022 Apr; 110(7):1173-1192.e7. PubMed ID: 35114102
[TBL] [Abstract][Full Text] [Related]
35. Length-dependent gametic CAG repeat instability in the Huntington's disease knock-in mouse.
Wheeler VC; Auerbach W; White JK; Srinidhi J; Auerbach A; Ryan A; Duyao MP; Vrbanac V; Weaver M; Gusella JF; Joyner AL; MacDonald ME
Hum Mol Genet; 1999 Jan; 8(1):115-22. PubMed ID: 9887339
[TBL] [Abstract][Full Text] [Related]
36. Novel allele-specific quantification methods reveal no effects of adult onset CAG repeats on HTT mRNA and protein levels.
Shin A; Shin B; Shin JW; Kim KH; Atwal RS; Hope JM; Gillis T; Leszyk JD; Shaffer SA; Lee R; Kwak S; MacDonald ME; Gusella JF; Seong IS; Lee JM
Hum Mol Genet; 2017 Apr; 26(7):1258-1267. PubMed ID: 28165127
[TBL] [Abstract][Full Text] [Related]
37. Interrupting sequence variants and age of onset in Huntington's disease: clinical implications and emerging therapies.
Wright GEB; Black HF; Collins JA; Gall-Duncan T; Caron NS; Pearson CE; Hayden MR
Lancet Neurol; 2020 Nov; 19(11):930-939. PubMed ID: 33098802
[TBL] [Abstract][Full Text] [Related]
38. Early Neurodegeneration in R6/2 Mice Carrying the Huntington's Disease Mutation with a Super-Expanded CAG Repeat, Despite Normal Lifespan.
Kielar C; Morton AJ
J Huntingtons Dis; 2018; 7(1):61-76. PubMed ID: 29480204
[TBL] [Abstract][Full Text] [Related]
39. Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels.
Rué L; Bañez-Coronel M; Creus-Muncunill J; Giralt A; Alcalá-Vida R; Mentxaka G; Kagerbauer B; Zomeño-Abellán MT; Aranda Z; Venturi V; Pérez-Navarro E; Estivill X; Martí E
J Clin Invest; 2016 Nov; 126(11):4319-4330. PubMed ID: 27721240
[TBL] [Abstract][Full Text] [Related]
40. Transcriptional correlates of the pathological phenotype in a Huntington's disease mouse model.
Gallardo-Orihuela A; Hervás-Corpión I; Hierro-Bujalance C; Sanchez-Sotano D; Jiménez-Gómez G; Mora-López F; Campos-Caro A; Garcia-Alloza M; Valor LM
Sci Rep; 2019 Dec; 9(1):18696. PubMed ID: 31822756
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
