These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
187 related articles for article (PubMed ID: 32061104)
1. Novel Abs targeting the N-terminus of fibroblast growth factor 19 inhibit hepatocellular carcinoma growth without bile-acid-related side-effects. Liu H; Zheng S; Hou X; Liu X; Du K; Lv X; Li Y; Yang F; Li W; Sui J Cancer Sci; 2020 May; 111(5):1750-1760. PubMed ID: 32061104 [TBL] [Abstract][Full Text] [Related]
2. Targeted inhibition of the FGF19-FGFR4 pathway in hepatocellular carcinoma; translational safety considerations. Mellor HR Liver Int; 2014 Jul; 34(6):e1-9. PubMed ID: 24393342 [TBL] [Abstract][Full Text] [Related]
3. FGF401 and vinorelbine synergistically mediate antitumor activity and vascular normalization in FGF19-dependent hepatocellular carcinoma. Huynh H; Prawira A; Le TBU; Vu TC; Hao HX; Huang A; Wang Y; Porta DG Exp Mol Med; 2020 Nov; 52(11):1857-1868. PubMed ID: 33235319 [TBL] [Abstract][Full Text] [Related]
4. Antibody-mediated inhibition of fibroblast growth factor 19 results in increased bile acids synthesis and ileal malabsorption of bile acids in cynomolgus monkeys. Pai R; French D; Ma N; Hotzel K; Plise E; Salphati L; Setchell KD; Ware J; Lauriault V; Schutt L; Hartley D; Dambach D Toxicol Sci; 2012 Apr; 126(2):446-56. PubMed ID: 22268002 [TBL] [Abstract][Full Text] [Related]
5. H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma. Joshi JJ; Coffey H; Corcoran E; Tsai J; Huang CL; Ichikawa K; Prajapati S; Hao MH; Bailey S; Wu J; Rimkunas V; Karr C; Subramanian V; Kumar P; MacKenzie C; Hurley R; Satoh T; Yu K; Park E; Rioux N; Kim A; Lai WG; Yu L; Zhu P; Buonamici S; Larsen N; Fekkes P; Wang J; Warmuth M; Reynolds DJ; Smith PG; Selvaraj A Cancer Res; 2017 Dec; 77(24):6999-7013. PubMed ID: 29247039 [TBL] [Abstract][Full Text] [Related]
6. First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway. Hagel M; Miduturu C; Sheets M; Rubin N; Weng W; Stransky N; Bifulco N; Kim JL; Hodous B; Brooijmans N; Shutes A; Winter C; Lengauer C; Kohl NE; Guzi T Cancer Discov; 2015 Apr; 5(4):424-37. PubMed ID: 25776529 [TBL] [Abstract][Full Text] [Related]
7. Identification of a therapeutic strategy targeting amplified FGF19 in liver cancer by Oncogenomic screening. Sawey ET; Chanrion M; Cai C; Wu G; Zhang J; Zender L; Zhao A; Busuttil RW; Yee H; Stein L; French DM; Finn RS; Lowe SW; Powers S Cancer Cell; 2011 Mar; 19(3):347-58. PubMed ID: 21397858 [TBL] [Abstract][Full Text] [Related]
8. The gut-liver axis in hepatocarcinoma: a focus on the nuclear receptor FXR and the enterokine FGF19. Piglionica M; Cariello M; Moschetta A Curr Opin Pharmacol; 2018 Dec; 43():93-98. PubMed ID: 30223181 [TBL] [Abstract][Full Text] [Related]
9. Fibroblast growth factor 19 expression correlates with tumor progression and poorer prognosis of hepatocellular carcinoma. Miura S; Mitsuhashi N; Shimizu H; Kimura F; Yoshidome H; Otsuka M; Kato A; Shida T; Okamura D; Miyazaki M BMC Cancer; 2012 Feb; 12():56. PubMed ID: 22309595 [TBL] [Abstract][Full Text] [Related]
10. Implications of FGF19 on sorafenib-mediated nitric oxide production in hepatocellular carcinoma cells - a short report. Gao L; Shay C; Lv F; Wang X; Teng Y Cell Oncol (Dordr); 2018 Feb; 41(1):85-91. PubMed ID: 28983785 [TBL] [Abstract][Full Text] [Related]
11. Separating Tumorigenicity from Bile Acid Regulatory Activity for Endocrine Hormone FGF19. Zhou M; Wang X; Phung V; Lindhout DA; Mondal K; Hsu JY; Yang H; Humphrey M; Ding X; Arora T; Learned RM; DePaoli AM; Tian H; Ling L Cancer Res; 2014 Jun; 74(12):3306-16. PubMed ID: 24728076 [TBL] [Abstract][Full Text] [Related]
12. Lenvatinib induces death of human hepatocellular carcinoma cells harboring an activated FGF signaling pathway through inhibition of FGFR-MAPK cascades. Hoshi T; Watanabe Miyano S; Watanabe H; Sonobe RMK; Seki Y; Ohta E; Nomoto K; Matsui J; Funahashi Y Biochem Biophys Res Commun; 2019 May; 513(1):1-7. PubMed ID: 30944079 [TBL] [Abstract][Full Text] [Related]
13. Non-cell-autonomous activation of IL-6/STAT3 signaling mediates FGF19-driven hepatocarcinogenesis. Zhou M; Yang H; Learned RM; Tian H; Ling L Nat Commun; 2017 May; 8():15433. PubMed ID: 28508871 [TBL] [Abstract][Full Text] [Related]
14. ASP5878, a Novel Inhibitor of FGFR1, 2, 3, and 4, Inhibits the Growth of FGF19-Expressing Hepatocellular Carcinoma. Futami T; Okada H; Kihara R; Kawase T; Nakayama A; Suzuki T; Kameda M; Shindoh N; Terasaka T; Hirano M; Kuromitsu S Mol Cancer Ther; 2017 Jan; 16(1):68-75. PubMed ID: 27837028 [TBL] [Abstract][Full Text] [Related]
15. Up-regulation of FGF15/19 signaling promotes hepatocellular carcinoma in the background of fatty liver. Cui G; Martin RC; Jin H; Liu X; Pandit H; Zhao H; Cai L; Zhang P; Li W; Li Y J Exp Clin Cancer Res; 2018 Jul; 37(1):136. PubMed ID: 29973237 [TBL] [Abstract][Full Text] [Related]
16. First-in-Human Phase I Study of Fisogatinib (BLU-554) Validates Aberrant FGF19 Signaling as a Driver Event in Hepatocellular Carcinoma. Kim RD; Sarker D; Meyer T; Yau T; Macarulla T; Park JW; Choo SP; Hollebecque A; Sung MW; Lim HY; Mazzaferro V; Trojan J; Zhu AX; Yoon JH; Sharma S; Lin ZZ; Chan SL; Faivre S; Feun LG; Yen CJ; Dufour JF; Palmer DH; Llovet JM; Manoogian M; Tugnait M; Stransky N; Hagel M; Kohl NE; Lengauer C; Sherwin CA; Schmidt-Kittler O; Hoeflich KP; Shi H; Wolf BB; Kang YK Cancer Discov; 2019 Dec; 9(12):1696-1707. PubMed ID: 31575541 [TBL] [Abstract][Full Text] [Related]
17. Suppression of Hepatic Bile Acid Synthesis by a non-tumorigenic FGF19 analogue Protects Mice from Fibrosis and Hepatocarcinogenesis. Gadaleta RM; Scialpi N; Peres C; Cariello M; Ko B; Luo J; Porru E; Roda A; Sabbà C; Moschetta A Sci Rep; 2018 Nov; 8(1):17210. PubMed ID: 30464200 [TBL] [Abstract][Full Text] [Related]
18. Up-regulation of fibroblast growth factor 19 and its receptor associates with progression from fatty liver to hepatocellular carcinoma. Li Y; Zhang W; Doughtie A; Cui G; Li X; Pandit H; Yang Y; Li S; Martin R Oncotarget; 2016 Aug; 7(32):52329-52339. PubMed ID: 27447573 [TBL] [Abstract][Full Text] [Related]
19. FGF19/FGFR4 signaling contributes to the resistance of hepatocellular carcinoma to sorafenib. Gao L; Wang X; Tang Y; Huang S; Hu CA; Teng Y J Exp Clin Cancer Res; 2017 Jan; 36(1):8. PubMed ID: 28069043 [TBL] [Abstract][Full Text] [Related]
20. FGF19 Protects Hepatocellular Carcinoma Cells against Endoplasmic Reticulum Stress via Activation of FGFR4-GSK3β-Nrf2 Signaling. Teng Y; Zhao H; Gao L; Zhang W; Shull AY; Shay C Cancer Res; 2017 Nov; 77(22):6215-6225. PubMed ID: 28951455 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]