BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 32064930)

  • 1. Structural and functional regulation of lactate dehydrogenase-A in cancer.
    Woodford MR; Chen VZ; Backe SJ; Bratslavsky G; Mollapour M
    Future Med Chem; 2020 Mar; 12(5):439-455. PubMed ID: 32064930
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms.
    Kolappan S; Shen DL; Mosi R; Sun J; McEachern EJ; Vocadlo DJ; Craig L
    Acta Crystallogr D Biol Crystallogr; 2015 Feb; 71(Pt 2):185-95. PubMed ID: 25664730
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Double genetic disruption of lactate dehydrogenases A and B is required to ablate the "Warburg effect" restricting tumor growth to oxidative metabolism.
    Ždralević M; Brand A; Di Ianni L; Dettmer K; Reinders J; Singer K; Peter K; Schnell A; Bruss C; Decking SM; Koehl G; Felipe-Abrio B; Durivault J; Bayer P; Evangelista M; O'Brien T; Oefner PJ; Renner K; Pouysségur J; Kreutz M
    J Biol Chem; 2018 Oct; 293(41):15947-15961. PubMed ID: 30158244
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Suppression of lactate dehydrogenase A compromises tumor progression by downregulation of the Warburg effect in glioblastoma.
    Li J; Zhu S; Tong J; Hao H; Yang J; Liu Z; Wang Y
    Neuroreport; 2016 Jan; 27(2):110-5. PubMed ID: 26694942
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lactate dehydrogenase A: A key player in carcinogenesis and potential target in cancer therapy.
    Feng Y; Xiong Y; Qiao T; Li X; Jia L; Han Y
    Cancer Med; 2018 Dec; 7(12):6124-6136. PubMed ID: 30403008
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human lactate dehydrogenase a inhibitors: a molecular dynamics investigation.
    Shi Y; Pinto BM
    PLoS One; 2014; 9(1):e86365. PubMed ID: 24466056
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Novel Lactate Dehydrogenase Inhibitor, 1-(Phenylseleno)-4-(Trifluoromethyl) Benzene, Suppresses Tumor Growth through Apoptotic Cell Death.
    Kim EY; Chung TW; Han CW; Park SY; Park KH; Jang SB; Ha KT
    Sci Rep; 2019 Mar; 9(1):3969. PubMed ID: 30850682
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Unappreciated Role of LDHA and LDHB to Control Apoptosis and Autophagy in Tumor Cells.
    Urbańska K; Orzechowski A
    Int J Mol Sci; 2019 Apr; 20(9):. PubMed ID: 31035592
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of LDHA suppresses cell proliferation and increases mitochondrial apoptosis via the JNK signaling pathway in cervical cancer cells.
    Zhang W; Wang C; Hu X; Lian Y; Ding C; Ming L
    Oncol Rep; 2022 Apr; 47(4):. PubMed ID: 35191522
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Exploring the Key Amino Acid Residues Surrounding the Active Center of Lactate Dehydrogenase A for the Development of Ideal Inhibitors.
    Chen J; Chen C; Zhang Z; Zeng F; Zhang S
    Molecules; 2024 Apr; 29(9):. PubMed ID: 38731521
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Metabolic Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes by Inhibition of HIF1α and LDHA.
    Hu D; Linders A; Yamak A; Correia C; Kijlstra JD; Garakani A; Xiao L; Milan DJ; van der Meer P; Serra M; Alves PM; Domian IJ
    Circ Res; 2018 Oct; 123(9):1066-1079. PubMed ID: 30355156
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Stable shRNA Silencing of Lactate Dehydrogenase A (LDHA) in Human MDA-MB-231 Breast Cancer Cells Fails to Alter Lactic Acid Production, Glycolytic Activity, ATP or Survival.
    Mack N; Mazzio EA; Bauer D; Flores-Rozas H; Soliman KF
    Anticancer Res; 2017 Mar; 37(3):1205-1212. PubMed ID: 28314283
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Fragment growing and linking lead to novel nanomolar lactate dehydrogenase inhibitors.
    Kohlmann A; Zech SG; Li F; Zhou T; Squillace RM; Commodore L; Greenfield MT; Lu X; Miller DP; Huang WS; Qi J; Thomas RM; Wang Y; Zhang S; Dodd R; Liu S; Xu R; Xu Y; Miret JJ; Rivera V; Clackson T; Shakespeare WC; Zhu X; Dalgarno DC
    J Med Chem; 2013 Feb; 56(3):1023-40. PubMed ID: 23302067
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression.
    Le A; Cooper CR; Gouw AM; Dinavahi R; Maitra A; Deck LM; Royer RE; Vander Jagt DL; Semenza GL; Dang CV
    Proc Natl Acad Sci U S A; 2010 Feb; 107(5):2037-42. PubMed ID: 20133848
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and initial screening of lactate dehydrogenase inhibitor activity of 1,3-benzodioxole derivatives.
    Annas D; Cheon SY; Yusuf M; Bae SJ; Ha KT; Park KH
    Sci Rep; 2020 Nov; 10(1):19889. PubMed ID: 33199724
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lactate dehydrogenase A negatively regulated by miRNAs promotes aerobic glycolysis and is increased in colorectal cancer.
    Wang J; Wang H; Liu A; Fang C; Hao J; Wang Z
    Oncotarget; 2015 Aug; 6(23):19456-68. PubMed ID: 26062441
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Regulation and Function of Lactate Dehydrogenase A: Therapeutic Potential in Brain Tumor.
    Valvona CJ; Fillmore HL; Nunn PB; Pilkington GJ
    Brain Pathol; 2016 Jan; 26(1):3-17. PubMed ID: 26269128
    [TBL] [Abstract][Full Text] [Related]  

  • 18. H
    Untereiner AA; Oláh G; Módis K; Hellmich MR; Szabo C
    Biochem Pharmacol; 2017 Jul; 136():86-98. PubMed ID: 28404377
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of LDHA suppresses tumor progression in prostate cancer.
    Xian ZY; Liu JM; Chen QK; Chen HZ; Ye CJ; Xue J; Yang HQ; Li JL; Liu XF; Kuang SJ
    Tumour Biol; 2015 Sep; 36(10):8093-100. PubMed ID: 25983002
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lactate dehydrogenase A in cancer: a promising target for diagnosis and therapy.
    Miao P; Sheng S; Sun X; Liu J; Huang G
    IUBMB Life; 2013 Nov; 65(11):904-10. PubMed ID: 24265197
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.