162 related articles for article (PubMed ID: 32087465)
1. Piperidine propionamide as a scaffold for potent sigma-1 receptor antagonists and mu opioid receptor agonists for treating neuropathic pain.
Xiong J; Jin J; Gao L; Hao C; Liu X; Liu BF; Chen Y; Zhang G
Eur J Med Chem; 2020 Apr; 191():112144. PubMed ID: 32087465
[TBL] [Abstract][Full Text] [Related]
2. Optimization of bifunctional piperidinamide derivatives as σ
Xiong J; Zhuang T; Ma Y; Xu J; Ye J; Ma R; Zhang S; Liu X; Liu BF; Hao C; Zhang G; Chen Y
Eur J Med Chem; 2021 Dec; 226():113879. PubMed ID: 34628236
[TBL] [Abstract][Full Text] [Related]
3. Propionamide Derivatives as Dual μ-Opioid Receptor Agonists and σ
García M; Llorente V; Garriga L; Christmann U; Rodríguez-Escrich S; Virgili M; Fernández B; Bordas M; Ayet E; Burgueño J; Pujol M; Dordal A; Portillo-Salido E; Gris G; Vela JM; Almansa C
J Med Chem; 2021 Jul; 64(14):10139-10154. PubMed ID: 34236190
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and biological evaluation of novel sigma-1 receptor antagonists based on pyrimidine scaffold as agents for treating neuropathic pain.
Lan Y; Chen Y; Cao X; Zhang J; Wang J; Xu X; Qiu Y; Zhang T; Liu X; Liu BF; Zhang G
J Med Chem; 2014 Dec; 57(24):10404-23. PubMed ID: 25420090
[TBL] [Abstract][Full Text] [Related]
5. Enkephalin analogues with N-phenyl-N-(piperidin-2-ylmethyl)propionamide derivatives: Synthesis and biological evaluations.
Deekonda S; Cole J; Sunna S; Rankin D; Largent-Milnes TM; Davis P; BassiriRad NM; Lai J; Vanderah TW; Porecca F; Hruby VJ
Bioorg Med Chem Lett; 2016 Jan; 26(1):222-7. PubMed ID: 26611918
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and Biological Evaluation of Novel σ1 Receptor Ligands for Treating Neuropathic Pain: 6-Hydroxypyridazinones.
Cao X; Chen Y; Zhang Y; Lan Y; Zhang J; Xu X; Qiu Y; Zhao S; Liu X; Liu BF; Zhang G
J Med Chem; 2016 Apr; 59(7):2942-61. PubMed ID: 27003636
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and Biological Evaluation of Sigma-1 (σ
Cao X; Yao Z; Dou F; Zhang Y; Qiu Y; Zhao S; Xu X; Liu X; Liu BF; Chen Y; Zhang G
Chem Biodivers; 2019 Mar; 16(3):e1800599. PubMed ID: 30549193
[TBL] [Abstract][Full Text] [Related]
8. Development of novel phenoxyalkylpiperidines as high-affinity Sigma-1 (σ
Abatematteo FS; Mosier PD; Niso M; Brunetti L; Berardi F; Loiodice F; Contino M; Delprat B; Maurice T; Laghezza A; Abate C
Eur J Med Chem; 2022 Jan; 228():114038. PubMed ID: 34902734
[TBL] [Abstract][Full Text] [Related]
9. Discovery of 5-substituted tetrahydronaphthalen-2yl-methyl with N-phenyl-N-(piperidin-4-yl)propionamide derivatives as potent opioid receptor ligands.
Deekonda S; Wugalter L; Kulkarni V; Rankin D; Largent-Milnes TM; Davis P; Bassirirad NM; Lai J; Vanderah TW; Porreca F; Hruby VJ
Bioorg Med Chem; 2015 Sep; 23(18):6185-94. PubMed ID: 26299827
[TBL] [Abstract][Full Text] [Related]
10. Design synthesis and structure-activity relationship of 5-substituted (tetrahydronaphthalen-2yl)methyl with N-phenyl-N-(piperidin-2-yl)propionamide derivatives as opioid ligands.
Deekonda S; Rankin D; Davis P; Lai J; Vanderah TW; Porecca F; Hruby VJ
Bioorg Med Chem; 2016 Jan; 24(2):85-91. PubMed ID: 26712115
[TBL] [Abstract][Full Text] [Related]
11. Improving selectivity preserving affinity: new piperidine-4-carboxamide derivatives as effective sigma-1-ligands.
Zampieri D; Laurini E; Vio L; Fermeglia M; Pricl S; Wünsch B; Schepmann D; Mamolo MG
Eur J Med Chem; 2015 Jan; 90():797-808. PubMed ID: 25528334
[TBL] [Abstract][Full Text] [Related]
12. Benzylaminofentanyl derivates: Discovery of bifunctional μ opioid and σ
Zhuang T; Xiong J; Ren X; Liang L; Qi Z; Zhang S; Du W; Chen Y; Liu X; Zhang G
Eur J Med Chem; 2022 Nov; 241():114649. PubMed ID: 35961067
[TBL] [Abstract][Full Text] [Related]
13. Pharmacological and metabolic characterisation of the potent sigma1 receptor ligand 1'-benzyl-3-methoxy-3H-spiro[[2]benzofuran-1,4'-piperidine].
Wiese C; Grosse Maestrup E; Schepmann D; Vela JM; Holenz J; Buschmann H; Wünsch B
J Pharm Pharmacol; 2009 May; 61(5):631-40. PubMed ID: 19406002
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and biological evaluation of a novel sigma-1 receptor antagonist based on 3,4-dihydro-2(1H)-quinolinone scaffold as a potential analgesic.
Lan Y; Chen Y; Xu X; Qiu Y; Liu S; Liu X; Liu BF; Zhang G
Eur J Med Chem; 2014 May; 79():216-30. PubMed ID: 24735647
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and receptor binding studies of some new arylcarboxamide derivatives as sigma-1 ligands.
Zampieri D; Laurini E; Vio L; Golob S; Fermeglia M; Pricl S; Mamolo MG
Bioorg Med Chem Lett; 2014 Feb; 24(4):1021-5. PubMed ID: 24486131
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and biological evaluation of novel 6,7-dihydro-5H-cyclopenta[d]pyrimidine and 5,6,7,8-tetrahydroquinazoline derivatives as sigma-1 (σ1) receptor antagonists for the treatment of pain.
Lan Y; Songyang Y; Zhang L; Peng Y; Song J
Bioorg Med Chem Lett; 2016 Apr; 26(8):2051-6. PubMed ID: 26947609
[TBL] [Abstract][Full Text] [Related]
17. High-affinity sigma-1 (σ
Niso M; Mosier PD; Marottoli R; Ferorelli S; Cassano G; Gasparre G; Leopoldo M; Berardi F; Abate C
Future Med Chem; 2019 Oct; 11(19):2547-2562. PubMed ID: 31633399
[No Abstract] [Full Text] [Related]
18. Synthesis and quantitative structure-activity relationships of N-(1-benzylpiperidin-4-yl)phenylacetamides and related analogues as potent and selective sigma1 receptor ligands.
Huang Y; Hammond PS; Whirrett BR; Kuhner RJ; Wu L; Childers SR; Mach RH
J Med Chem; 1998 Jun; 41(13):2361-70. PubMed ID: 9632369
[TBL] [Abstract][Full Text] [Related]
19. 4-Aryl-1-oxa-4,9-diazaspiro[5.5]undecane Derivatives as Dual μ-Opioid Receptor Agonists and σ
García M; Virgili M; Alonso M; Alegret C; Fernández B; Port A; Pascual R; Monroy X; Vidal-Torres A; Serafini MT; Vela JM; Almansa C
J Med Chem; 2020 Mar; 63(5):2434-2454. PubMed ID: 31743642
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and evaluation of a 18F-labeled spirocyclic piperidine derivative as promising σ1 receptor imaging agent.
Chen YY; Wang X; Zhang JM; Deuther-Conrad W; Zhang XJ; Huang Y; Li Y; Ye JJ; Cui MC; Steinbach J; Brust P; Liu BL; Jia HM
Bioorg Med Chem; 2014 Oct; 22(19):5270-8. PubMed ID: 25189691
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
