245 related articles for article (PubMed ID: 32091206)
1. Structural Basis of Inhibitor Selectivity in the BRD7/9 Subfamily of Bromodomains.
Karim RM; Chan A; Zhu JY; Schönbrunn E
J Med Chem; 2020 Mar; 63(6):3227-3237. PubMed ID: 32091206
[TBL] [Abstract][Full Text] [Related]
2. Application of Atypical Acetyl-lysine Methyl Mimetics in the Development of Selective Inhibitors of the Bromodomain-Containing Protein 7 (BRD7)/Bromodomain-Containing Protein 9 (BRD9) Bromodomains.
Clegg MA; Bamborough P; Chung CW; Craggs PD; Gordon L; Grandi P; Leveridge M; Lindon M; Liwicki GM; Michon AM; Molnar J; Rioja I; Soden PE; Theodoulou NH; Werner T; Tomkinson NCO; Prinjha RK; Humphreys PG
J Med Chem; 2020 Jun; 63(11):5816-5840. PubMed ID: 32410449
[TBL] [Abstract][Full Text] [Related]
3. LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor.
Clark PG; Vieira LC; Tallant C; Fedorov O; Singleton DC; Rogers CM; Monteiro OP; Bennett JM; Baronio R; Müller S; Daniels DL; Méndez J; Knapp S; Brennan PE; Dixon DJ
Angew Chem Int Ed Engl; 2015 May; 54(21):6217-21. PubMed ID: 25864491
[TBL] [Abstract][Full Text] [Related]
4. Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition.
Theodoulou NH; Bamborough P; Bannister AJ; Becher I; Bit RA; Che KH; Chung CW; Dittmann A; Drewes G; Drewry DH; Gordon L; Grandi P; Leveridge M; Lindon M; Michon AM; Molnar J; Robson SC; Tomkinson NC; Kouzarides T; Prinjha RK; Humphreys PG
J Med Chem; 2016 Feb; 59(4):1425-39. PubMed ID: 25856009
[TBL] [Abstract][Full Text] [Related]
5. Development of chemical probes for the bromodomains of BRD7 and BRD9.
Clark PG; Dixon DJ; Brennan PE
Drug Discov Today Technol; 2016 Mar; 19():73-80. PubMed ID: 27769361
[TBL] [Abstract][Full Text] [Related]
6. NMR Fragment Screening Hit Induces Plasticity of BRD7/9 Bromodomains.
Wang N; Li F; Bao H; Li J; Wu J; Ruan K
Chembiochem; 2016 Aug; 17(15):1456-63. PubMed ID: 27194508
[TBL] [Abstract][Full Text] [Related]
7. Rational Design and Development of Selective BRD7 Bromodomain Inhibitors and Their Activity in Prostate Cancer.
Ordonez-Rubiano SC; Maschinot CA; Wang S; Sood S; Baracaldo-Lancheros LF; Strohmier BP; McQuade AJ; Smith BC; Dykhuizen EC
J Med Chem; 2023 Aug; 66(16):11250-11270. PubMed ID: 37552884
[TBL] [Abstract][Full Text] [Related]
8. Insight into selective mechanism of class of I-BRD9 inhibitors toward BRD9 based on molecular dynamics simulations.
Su J; Liu X; Zhang S; Yan F; Zhang Q; Chen J
Chem Biol Drug Des; 2019 Feb; 93(2):163-176. PubMed ID: 30225973
[TBL] [Abstract][Full Text] [Related]
9. Epigenetic modulation by targeting bromodomain containing protein 9 (BRD9): Its therapeutic potential and selective inhibition.
Ali MM; Naz S; Ashraf S; Knapp S; Ul-Haq Z
Int J Biol Macromol; 2023 Mar; 230():123428. PubMed ID: 36709803
[TBL] [Abstract][Full Text] [Related]
10. Biological function and histone recognition of family IV bromodomain-containing proteins.
Lloyd JT; Glass KC
J Cell Physiol; 2018 Mar; 233(3):1877-1886. PubMed ID: 28500727
[TBL] [Abstract][Full Text] [Related]
11. 4-Acyl Pyrroles as Dual BET-BRD7/9 Bromodomain Inhibitors Address BETi Insensitive Human Cancer Cell Lines.
Hügle M; Regenass P; Warstat R; Hau M; Schmidtkunz K; Lucas X; Wohlwend D; Einsle O; Jung M; Breit B; Günther S
J Med Chem; 2020 Dec; 63(24):15603-15620. PubMed ID: 33275431
[TBL] [Abstract][Full Text] [Related]
12. Characterization of the Functional Interplay between the BRD7 and BRD9 Homologues in mSWI/SNF Complexes.
Agbo L; Loehr J; Kougnassoukou Tchara PE; Lambert JP
J Proteome Res; 2023 Jan; 22(1):78-90. PubMed ID: 36484504
[TBL] [Abstract][Full Text] [Related]
13. Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor.
Martin LJ; Koegl M; Bader G; Cockcroft XL; Fedorov O; Fiegen D; Gerstberger T; Hofmann MH; Hohmann AF; Kessler D; Knapp S; Knesl P; Kornigg S; Müller S; Nar H; Rogers C; Rumpel K; Schaaf O; Steurer S; Tallant C; Vakoc CR; Zeeb M; Zoephel A; Pearson M; Boehmelt G; McConnell D
J Med Chem; 2016 May; 59(10):4462-75. PubMed ID: 26914985
[TBL] [Abstract][Full Text] [Related]
14. LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor.
Clark PG; Vieira LC; Tallant C; Fedorov O; Singleton DC; Rogers CM; Monteiro OP; Bennett JM; Baronio R; Müller S; Daniels DL; Méndez J; Knapp S; Brennan PE; Dixon DJ
Angew Chem Weinheim Bergstr Ger; 2015 May; 127(21):6315-6319. PubMed ID: 27346896
[TBL] [Abstract][Full Text] [Related]
15. Theoretical exploration of the binding selectivity of inhibitors to BRD7 and BRD9 with multiple short molecular dynamics simulations.
Wang L; Wang Y; Zhao J; Yu Y; Kang N; Yang Z
RSC Adv; 2022 Jun; 12(26):16663-16676. PubMed ID: 35754900
[TBL] [Abstract][Full Text] [Related]
16. Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel-Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7.
Zoppi V; Hughes SJ; Maniaci C; Testa A; Gmaschitz T; Wieshofer C; Koegl M; Riching KM; Daniels DL; Spallarossa A; Ciulli A
J Med Chem; 2019 Jan; 62(2):699-726. PubMed ID: 30540463
[TBL] [Abstract][Full Text] [Related]
17. Research progress of selective small molecule bromodomain-containing protein 9 inhibitors.
Hui M; Jian Z; Peiyuan Z; Zhenwei W; Huibin Z
Future Med Chem; 2018 Apr; 10(8):895-906. PubMed ID: 29620420
[TBL] [Abstract][Full Text] [Related]
18. Chemical Proteomic Profiling of Bromodomains Enables the Wide-Spectrum Evaluation of Bromodomain Inhibitors in Living Cells.
Li X; Wu Y; Tian G; Jiang Y; Liu Z; Meng X; Bao X; Feng L; Sun H; Deng H; Li XD
J Am Chem Soc; 2019 Jul; 141(29):11497-11505. PubMed ID: 31246451
[TBL] [Abstract][Full Text] [Related]
19. In silico design and molecular basis for the selectivity of Olinone toward the first over the second bromodomain of BRD4.
Rodríguez Y; Gerona-Navarro G; Osman R; Zhou MM
Proteins; 2020 Mar; 88(3):414-430. PubMed ID: 31587361
[TBL] [Abstract][Full Text] [Related]
20. Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors.
Karim RM; Bikowitz MJ; Chan A; Zhu JY; Grassie D; Becker A; Berndt N; Gunawan S; Lawrence NJ; Schönbrunn E
J Med Chem; 2021 Nov; 64(21):15772-15786. PubMed ID: 34710325
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
