194 related articles for article (PubMed ID: 32093602)
1. Combining feature selection and shape analysis uncovers precise rules for miRNA regulation in Huntington's disease mice.
Mégret L; Nair SS; Dancourt J; Aaronson J; Rosinski J; Neri C
BMC Bioinformatics; 2020 Feb; 21(1):75. PubMed ID: 32093602
[TBL] [Abstract][Full Text] [Related]
2. Cellular Analysis of Silencing the Huntington's Disease Gene Using AAV9 Mediated Delivery of Artificial Micro RNA into the Striatum of Q140/Q140 Mice.
Keeler AM; Sapp E; Chase K; Sottosanti E; Danielson E; Pfister E; Stoica L; DiFiglia M; Aronin N; Sena-Esteves M
J Huntingtons Dis; 2016 Oct; 5(3):239-248. PubMed ID: 27689620
[TBL] [Abstract][Full Text] [Related]
3. Potent and sustained huntingtin lowering via AAV5 encoding miRNA preserves striatal volume and cognitive function in a humanized mouse model of Huntington disease.
Caron NS; Southwell AL; Brouwers CC; Cengio LD; Xie Y; Black HF; Anderson LM; Ko S; Zhu X; van Deventer SJ; Evers MM; Konstantinova P; Hayden MR
Nucleic Acids Res; 2020 Jan; 48(1):36-54. PubMed ID: 31745548
[TBL] [Abstract][Full Text] [Related]
4. Lack of huntingtin promotes neural stem cells differentiation into glial cells while neurons expressing huntingtin with expanded polyglutamine tracts undergo cell death.
Conforti P; Camnasio S; Mutti C; Valenza M; Thompson M; Fossale E; Zeitlin S; MacDonald ME; Zuccato C; Cattaneo E
Neurobiol Dis; 2013 Feb; 50():160-70. PubMed ID: 23089356
[TBL] [Abstract][Full Text] [Related]
5. Protein changes in synaptosomes of Huntington's disease knock-in mice are dependent on age and brain region.
Sapp E; Seeley C; Iuliano M; Weisman E; Vodicka P; DiFiglia M; Kegel-Gleason KB
Neurobiol Dis; 2020 Jul; 141():104950. PubMed ID: 32439598
[TBL] [Abstract][Full Text] [Related]
6. Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels.
Rué L; Bañez-Coronel M; Creus-Muncunill J; Giralt A; Alcalá-Vida R; Mentxaka G; Kagerbauer B; Zomeño-Abellán MT; Aranda Z; Venturi V; Pérez-Navarro E; Estivill X; Martí E
J Clin Invest; 2016 Nov; 126(11):4319-4330. PubMed ID: 27721240
[TBL] [Abstract][Full Text] [Related]
7. Altered microRNA regulation in Huntington's disease models.
Lee ST; Chu K; Im WS; Yoon HJ; Im JY; Park JE; Park KH; Jung KH; Lee SK; Kim M; Roh JK
Exp Neurol; 2011 Jan; 227(1):172-9. PubMed ID: 21035445
[TBL] [Abstract][Full Text] [Related]
8. Increased Steady-State Mutant Huntingtin mRNA in Huntington's Disease Brain.
Liu W; Chaurette J; Pfister EL; Kennington LA; Chase KO; Bullock J; Vonsattel JP; Faull RL; Macdonald D; DiFiglia M; Zamore PD; Aronin N
J Huntingtons Dis; 2013; 2(4):491-500. PubMed ID: 25062733
[TBL] [Abstract][Full Text] [Related]
9. AAV5-miHTT Gene Therapy Demonstrates Broad Distribution and Strong Human Mutant Huntingtin Lowering in a Huntington's Disease Minipig Model.
Evers MM; Miniarikova J; Juhas S; Vallès A; Bohuslavova B; Juhasova J; Skalnikova HK; Vodicka P; Valekova I; Brouwers C; Blits B; Lubelski J; Kovarova H; Ellederova Z; van Deventer SJ; Petry H; Motlik J; Konstantinova P
Mol Ther; 2018 Sep; 26(9):2163-2177. PubMed ID: 30007561
[TBL] [Abstract][Full Text] [Related]
10. Artificial miRNAs Reduce Human Mutant Huntingtin Throughout the Striatum in a Transgenic Sheep Model of Huntington's Disease.
Pfister EL; DiNardo N; Mondo E; Borel F; Conroy F; Fraser C; Gernoux G; Han X; Hu D; Johnson E; Kennington L; Liu P; Reid SJ; Sapp E; Vodicka P; Kuchel T; Morton AJ; Howland D; Moser R; Sena-Esteves M; Gao G; Mueller C; DiFiglia M; Aronin N
Hum Gene Ther; 2018 Jun; 29(6):663-673. PubMed ID: 29207890
[TBL] [Abstract][Full Text] [Related]
11. MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice.
Langfelder P; Gao F; Wang N; Howland D; Kwak S; Vogt TF; Aaronson JS; Rosinski J; Coppola G; Horvath S; Yang XW
PLoS One; 2018; 13(1):e0190550. PubMed ID: 29324753
[TBL] [Abstract][Full Text] [Related]
12. Partial resistance to malonate-induced striatal cell death in transgenic mouse models of Huntington's disease is dependent on age and CAG repeat length.
Hansson O; Castilho RF; Korhonen L; Lindholm D; Bates GP; Brundin P
J Neurochem; 2001 Aug; 78(4):694-703. PubMed ID: 11520890
[TBL] [Abstract][Full Text] [Related]
13. Dysregulated miRNA and mRNA Expression Affect Overlapping Pathways in a Huntington's Disease Model.
Zsindely N; Nagy G; Siági F; Farkas A; Bodai L
Int J Mol Sci; 2023 Jul; 24(15):. PubMed ID: 37569316
[TBL] [Abstract][Full Text] [Related]
14. Does the Mutant CAG Expansion in Huntingtin mRNA Interfere with Exonucleolytic Cleavage of its First Exon?
Liu W; Pfister EL; Kennington LA; Chase KO; Mueller C; DiFiglia M; Aronin N
J Huntingtons Dis; 2016; 5(1):33-8. PubMed ID: 27003665
[TBL] [Abstract][Full Text] [Related]
15. Lack of RAN-mediated toxicity in Huntington's disease knock-in mice.
Yang S; Yang H; Huang L; Chen L; Qin Z; Li S; Li XJ
Proc Natl Acad Sci U S A; 2020 Feb; 117(8):4411-4417. PubMed ID: 32029588
[TBL] [Abstract][Full Text] [Related]
16. Decrease in striatal enkephalin mRNA in mouse models of Huntington's disease.
Menalled L; Zanjani H; MacKenzie L; Koppel A; Carpenter E; Zeitlin S; Chesselet MF
Exp Neurol; 2000 Apr; 162(2):328-42. PubMed ID: 10739639
[TBL] [Abstract][Full Text] [Related]
17. Interrogation of brain miRNA and mRNA expression profiles reveals a molecular regulatory network that is perturbed by mutant huntingtin.
Jin J; Cheng Y; Zhang Y; Wood W; Peng Q; Hutchison E; Mattson MP; Becker KG; Duan W
J Neurochem; 2012 Nov; 123(4):477-90. PubMed ID: 22906125
[TBL] [Abstract][Full Text] [Related]
18. TRAX Provides Neuroprotection for Huntington's Disease Via Modulating a Novel Subset of MicroRNAs.
Weng YT; Chen HM; Chien T; Chiu FL; Kuo HC; Chern Y
Mov Disord; 2022 Oct; 37(10):2008-2020. PubMed ID: 35997316
[TBL] [Abstract][Full Text] [Related]
19. miR-10b-5p expression in Huntington's disease brain relates to age of onset and the extent of striatal involvement.
Hoss AG; Labadorf A; Latourelle JC; Kartha VK; Hadzi TC; Gusella JF; MacDonald ME; Chen JF; Akbarian S; Weng Z; Vonsattel JP; Myers RH
BMC Med Genomics; 2015 Mar; 8():10. PubMed ID: 25889241
[TBL] [Abstract][Full Text] [Related]
20. Genetic Contributors to Intergenerational CAG Repeat Instability in Huntington's Disease Knock-In Mice.
Neto JL; Lee JM; Afridi A; Gillis T; Guide JR; Dempsey S; Lager B; Alonso I; Wheeler VC; Pinto RM
Genetics; 2017 Feb; 205(2):503-516. PubMed ID: 27913616
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
