BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

279 related articles for article (PubMed ID: 32100577)

  • 1. Discovery of drugs that directly target the intrinsically disordered region of the androgen receptor.
    Sadar MD
    Expert Opin Drug Discov; 2020 May; 15(5):551-560. PubMed ID: 32100577
    [No Abstract]   [Full Text] [Related]  

  • 2. Sintokamide A Is a Novel Antagonist of Androgen Receptor That Uniquely Binds Activation Function-1 in Its Amino-terminal Domain.
    Banuelos CA; Tavakoli I; Tien AH; Caley DP; Mawji NR; Li Z; Wang J; Yang YC; Imamura Y; Yan L; Wen JG; Andersen RJ; Sadar MD
    J Biol Chem; 2016 Oct; 291(42):22231-22243. PubMed ID: 27576691
    [TBL] [Abstract][Full Text] [Related]  

  • 3. An androgen receptor N-terminal domain antagonist for treating prostate cancer.
    Myung JK; Banuelos CA; Fernandez JG; Mawji NR; Wang J; Tien AH; Yang YC; Tavakoli I; Haile S; Watt K; McEwan IJ; Plymate S; Andersen RJ; Sadar MD
    J Clin Invest; 2013 Jul; 123(7):2948-60. PubMed ID: 23722902
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Combination therapy with androgen receptor N-terminal domain antagonist EPI-7170 and enzalutamide yields synergistic activity in AR-V7-positive prostate cancer.
    Hirayama Y; Tam T; Jian K; Andersen RJ; Sadar MD
    Mol Oncol; 2020 Oct; 14(10):2455-2470. PubMed ID: 32734688
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development of a Benzothiazole Scaffold-Based Androgen Receptor N-Terminal Inhibitor for Treating Androgen-Responsive Prostate Cancer.
    Kuznik NC; Solozobova V; Jung N; Gräßle S; Lei Q; Lewandowski EM; Munuganti R; Zoubeidi A; Chen Y; Bräse S; Cato ACB
    ACS Chem Biol; 2021 Nov; 16(11):2103-2108. PubMed ID: 34506104
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A sting in the tail: the N-terminal domain of the androgen receptor as a drug target.
    Monaghan AE; McEwan IJ
    Asian J Androl; 2016; 18(5):687-94. PubMed ID: 27212126
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer.
    Dalal K; Roshan-Moniri M; Sharma A; Li H; Ban F; Hessein M; Hsing M; Singh K; LeBlanc E; Dehm S; Tomlinson Guns ES; Cherkasov A; Rennie PS
    J Biol Chem; 2014 Sep; 289(38):26417-26429. PubMed ID: 25086042
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Androgen receptor modulators: a review of recent patents and reports (2012-2018).
    Fujii S; Kagechika H
    Expert Opin Ther Pat; 2019 Jun; 29(6):439-453. PubMed ID: 31092069
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of niphatenones that inhibit androgen receptor N-terminal domain.
    Banuelos CA; Lal A; Tien AH; Shah N; Yang YC; Mawji NR; Meimetis LG; Park J; Kunzhong J; Andersen RJ; Sadar MD
    PLoS One; 2014; 9(9):e107991. PubMed ID: 25268119
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Development of a High-Throughput Screening Assay for Small-Molecule Inhibitors of Androgen Receptor Splice Variants.
    Monaghan AE; Porter A; Hunter I; Morrison A; McElroy SP; McEwan IJ
    Assay Drug Dev Technol; 2022 Apr; 20(3):111-124. PubMed ID: 35333596
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Intrinsic disorder in the androgen receptor: identification, characterisation and drugability.
    McEwan IJ
    Mol Biosyst; 2012 Jan; 8(1):82-90. PubMed ID: 21822504
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Topological dynamics of an intrinsically disordered N-terminal domain of the human androgen receptor.
    Sheikhhassani V; Scalvini B; Ng J; Heling LWHJ; Ayache Y; Evers TMJ; Estébanez-Perpiñá E; McEwan IJ; Mashaghi A
    Protein Sci; 2022 Jun; 31(6):e4334. PubMed ID: 35634773
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting the N-terminal domain of the androgen receptor: The effective approach in therapy of CRPC.
    Ji Y; Zhang R; Han X; Zhou J
    Eur J Med Chem; 2023 Feb; 247():115077. PubMed ID: 36587421
    [TBL] [Abstract][Full Text] [Related]  

  • 14. EPI-001 is a selective peroxisome proliferator-activated receptor-gamma modulator with inhibitory effects on androgen receptor expression and activity in prostate cancer.
    Brand LJ; Olson ME; Ravindranathan P; Guo H; Kempema AM; Andrews TE; Chen X; Raj GV; Harki DA; Dehm SM
    Oncotarget; 2015 Feb; 6(6):3811-24. PubMed ID: 25669987
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Small molecule inhibitors targeting the "achilles' heel" of androgen receptor activity.
    Sadar MD
    Cancer Res; 2011 Feb; 71(4):1208-13. PubMed ID: 21285252
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Beyond androgen deprivation: ancillary integrative strategies for targeting the androgen receptor addiction of prostate cancer.
    McCarty MF; Hejazi J; Rastmanesh R
    Integr Cancer Ther; 2014 Sep; 13(5):386-95. PubMed ID: 24867960
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeting the N-Terminal Domain of the Androgen Receptor: A New Approach for the Treatment of Advanced Prostate Cancer.
    Antonarakis ES; Chandhasin C; Osbourne E; Luo J; Sadar MD; Perabo F
    Oncologist; 2016 Dec; 21(12):1427-1435. PubMed ID: 27628492
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combined N-terminal androgen receptor and autophagy inhibition increases the antitumor effect in enzalutamide sensitive and enzalutamide resistant prostate cancer cells.
    Kranzbühler B; Salemi S; Mortezavi A; Sulser T; Eberli D
    Prostate; 2019 Feb; 79(2):206-214. PubMed ID: 30345525
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Moving Towards Precision Urologic Oncology: Targeting Enzalutamide-resistant Prostate Cancer and Mutated Forms of the Androgen Receptor Using the Novel Inhibitor Darolutamide (ODM-201).
    Borgmann H; Lallous N; Ozistanbullu D; Beraldi E; Paul N; Dalal K; Fazli L; Haferkamp A; Lejeune P; Cherkasov A; Gleave ME
    Eur Urol; 2018 Jan; 73(1):4-8. PubMed ID: 28851578
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Investigational therapies targeting the androgen signaling axis and the androgen receptor and in prostate cancer - recent developments and future directions.
    Isaacsson Velho P; Carducci MA
    Expert Opin Investig Drugs; 2018 Oct; 27(10):811-822. PubMed ID: 30118330
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.