BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

201 related articles for article (PubMed ID: 32101438)

  • 1. Dimerization of α-Conotoxins as a Strategy to Enhance the Inhibition of the Human α7 and α9α10 Nicotinic Acetylcholine Receptors.
    Liang J; Tae HS; Xu X; Jiang T; Adams DJ; Yu R
    J Med Chem; 2020 Mar; 63(6):2974-2985. PubMed ID: 32101438
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Alpha-RgIA, a novel conotoxin that blocks the alpha9alpha10 nAChR: structure and identification of key receptor-binding residues.
    Ellison M; Feng ZP; Park AJ; Zhang X; Olivera BM; McIntosh JM; Norton RS
    J Mol Biol; 2008 Apr; 377(4):1216-27. PubMed ID: 18295795
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel alpha-conotoxin, PeIA, cloned from Conus pergrandis, discriminates between rat alpha9alpha10 and alpha7 nicotinic cholinergic receptors.
    McIntosh JM; Plazas PV; Watkins M; Gomez-Casati ME; Olivera BM; Elgoyhen AB
    J Biol Chem; 2005 Aug; 280(34):30107-12. PubMed ID: 15983035
    [TBL] [Abstract][Full Text] [Related]  

  • 4. αS-conotoxin GVIIIB potently and selectively blocks α9α10 nicotinic acetylcholine receptors.
    Christensen SB; Bandyopadhyay PK; Olivera BM; McIntosh JM
    Biochem Pharmacol; 2015 Aug; 96(4):349-56. PubMed ID: 26074268
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular Determinants Conferring the Stoichiometric-Dependent Activity of α-Conotoxins at the Human α9α10 Nicotinic Acetylcholine Receptor Subtype.
    Yu R; Tae HS; Tabassum N; Shi J; Jiang T; Adams DJ
    J Med Chem; 2018 May; 61(10):4628-4634. PubMed ID: 29733583
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular interaction of α-conotoxin RgIA with the rat α9α10 nicotinic acetylcholine receptor.
    Azam L; Papakyriakou A; Zouridakis M; Giastas P; Tzartos SJ; McIntosh JM
    Mol Pharmacol; 2015 May; 87(5):855-64. PubMed ID: 25740413
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Species specificity of rat and human α7 nicotinic acetylcholine receptors towards different classes of peptide and protein antagonists.
    Yu J; Zhu X; Zhang L; Kudryavtsev D; Kasheverov I; Lei Y; Zhangsun D; Tsetlin V; Luo S
    Neuropharmacology; 2018 Sep; 139():226-237. PubMed ID: 30025921
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Orthosteric and/or Allosteric Binding of α-Conotoxins to Nicotinic Acetylcholine Receptors and Their Models.
    Kryukova EV; Ivanov IA; Lebedev DS; Spirova EN; Egorova NS; Zouridakis M; Kasheverov IE; Tzartos SJ; Tsetlin VI
    Mar Drugs; 2018 Nov; 16(12):. PubMed ID: 30469507
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Critical residue properties for potency and selectivity of α-Conotoxin RgIA towards α9α10 nicotinic acetylcholine receptors.
    Huynh PN; Harvey PJ; Gajewiak J; Craik DJ; Michael McIntosh J
    Biochem Pharmacol; 2020 Nov; 181():114124. PubMed ID: 32593612
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A synthetic combinatorial strategy for developing alpha-conotoxin analogs as potent alpha7 nicotinic acetylcholine receptor antagonists.
    Armishaw CJ; Singh N; Medina-Franco JL; Clark RJ; Scott KC; Houghten RA; Jensen AA
    J Biol Chem; 2010 Jan; 285(3):1809-21. PubMed ID: 19901032
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Substitution of D-Arginine at Position 11 of α-RgIA Potently Inhibits α7 Nicotinic Acetylcholine Receptor.
    Wu Y; Zhang J; Ren J; Zhu X; Li R; Zhangsun D; Luo S
    Mar Drugs; 2023 May; 21(6):. PubMed ID: 37367650
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular determinants of α-conotoxin potency for inhibition of human and rat α6β4 nicotinic acetylcholine receptors.
    Hone AJ; Talley TT; Bobango J; Huidobro Melo C; Hararah F; Gajewiak J; Christensen S; Harvey PJ; Craik DJ; McIntosh JM
    J Biol Chem; 2018 Nov; 293(46):17838-17852. PubMed ID: 30249616
    [TBL] [Abstract][Full Text] [Related]  

  • 13. αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtype.
    Zhangsun D; Zhu X; Kaas Q; Wu Y; Craik DJ; McIntosh JM; Luo S
    Neuropharmacology; 2017 Dec; 127():243-252. PubMed ID: 28416445
    [TBL] [Abstract][Full Text] [Related]  

  • 14. From Crystal Structures of RgIA4 in Complex with
    Pan S; Fan Y; Zhu X; Xue Y; Luo S; Wang X
    Mar Drugs; 2021 Dec; 19(12):. PubMed ID: 34940708
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Globular and ribbon isomers of Conus geographus α-conotoxins antagonize human nicotinic acetylcholine receptors.
    Tae HS; Gao B; Jin AH; Alewood PF; Adams DJ
    Biochem Pharmacol; 2021 Aug; 190():114638. PubMed ID: 34062129
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interaction of rat α9α10 nicotinic acetylcholine receptor with α-conotoxin RgIA and Vc1.1: Insights from docking, molecular dynamics and binding free energy contributions.
    Li R; Li X; Jiang J; Tian Y; Liu D; Zhangsun D; Fu Y; Wu Y; Luo S
    J Mol Graph Model; 2019 Nov; 92():55-64. PubMed ID: 31330438
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rational design of alpha-conotoxin analogues targeting alpha7 nicotinic acetylcholine receptors: improved antagonistic activity by incorporation of proline derivatives.
    Armishaw C; Jensen AA; Balle T; Clark RJ; Harpsøe K; Skonberg C; Liljefors T; Strømgaard K
    J Biol Chem; 2009 Apr; 284(14):9498-512. PubMed ID: 19131337
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of C-Terminal Carboxylation on α-Conotoxin LsIA Interactions with Human α7 Nicotinic Acetylcholine Receptor: Molecular Simulation Studies.
    Wen J; Hung A
    Mar Drugs; 2019 Apr; 17(4):. PubMed ID: 30987002
    [TBL] [Abstract][Full Text] [Related]  

  • 19. d-Amino Acid Substitution of α-Conotoxin RgIA Identifies its Critical Residues and Improves the Enzymatic Stability.
    Ren J; Zhu X; Xu P; Li R; Fu Y; Dong S; Zhangsun D; Wu Y; Luo S
    Mar Drugs; 2019 Feb; 17(3):. PubMed ID: 30823399
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Alpha-conotoxin analogs with additional positive charge show increased selectivity towards Torpedo californica and some neuronal subtypes of nicotinic acetylcholine receptors.
    Kasheverov IE; Zhmak MN; Vulfius CA; Gorbacheva EV; Mordvintsev DY; Utkin YN; van Elk R; Smit AB; Tsetlin VI
    FEBS J; 2006 Oct; 273(19):4470-81. PubMed ID: 16956365
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.