101 related articles for article (PubMed ID: 32104684)
1. Porcupine Inhibitor LGK974 Downregulates the Wnt Signaling Pathway and Inhibits Clear Cell Renal Cell Carcinoma.
Li J; Wu G; Xu Y; Li J; Ruan N; Chen Y; Zhang Q; Xia Q
Biomed Res Int; 2020; 2020():2527643. PubMed ID: 32104684
[TBL] [Abstract][Full Text] [Related]
2. Wnt family member 4 (WNT4) and WNT3A activate cell-autonomous Wnt signaling independent of porcupine
Rao DM; Shackleford MT; Bordeaux EK; Sottnik JL; Ferguson RL; Yamamoto TM; Wellberg EA; Bitler BG; Sikora MJ
J Biol Chem; 2019 Dec; 294(52):19950-19966. PubMed ID: 31740580
[TBL] [Abstract][Full Text] [Related]
3. Suppression of Wnt/β-Catenin Signaling Is Associated with Downregulation of Wnt1, PORCN, and Rspo2 in Alzheimer's Disease.
Macyczko JR; Wang N; Zhao J; Ren Y; Lu W; Ikezu TC; Zhao N; Liu CC; Bu G; Li Y
Mol Neurobiol; 2023 Jan; 60(1):26-35. PubMed ID: 36215026
[TBL] [Abstract][Full Text] [Related]
4. PORCN moonlights in a Wnt-independent pathway that regulates cancer cell proliferation.
Covey TM; Kaur S; Tan Ong T; Proffitt KD; Wu Y; Tan P; Virshup DM
PLoS One; 2012; 7(4):e34532. PubMed ID: 22509316
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of PORCN Blocks Wnt Signaling to Attenuate Progression of Oral Carcinogenesis.
Peña-Oyarzún D; Flores T; Torres VA; Quest AFG; Lobos-González L; Kretschmar C; Contreras P; Maturana-Ramírez A; Criollo A; Reyes M
Clin Cancer Res; 2024 Jan; 30(1):209-223. PubMed ID: 37812478
[TBL] [Abstract][Full Text] [Related]
6. LGK974 suppresses the formation of deep vein thrombosis in mice with sepsis.
Li Z; Shan X; Yang G; Dong L
Int Immunopharmacol; 2024 Jan; 127():111458. PubMed ID: 38160565
[TBL] [Abstract][Full Text] [Related]
7. ESM-1 Mediates Cell Progression in Clear Cell Renal Cell Carcinoma by Affecting Wnt/β-Catenin Signalling Pathway.
Liu X; Wang F; Du W; Yang X
Arch Esp Urol; 2023 Jun; 76(4):290-297. PubMed ID: 37455528
[TBL] [Abstract][Full Text] [Related]
8. Molecular genetics and targeted therapy of WNT-related human diseases (Review).
Katoh M; Katoh M
Int J Mol Med; 2017 Sep; 40(3):587-606. PubMed ID: 28731148
[TBL] [Abstract][Full Text] [Related]
9. Knockdown of
Xin H; Tang Y; Jin YH; Li HL; Tian Y; Yu C; Zhao ZJ; Wu MS; Pan YF
Cell Adh Migr; 2023 Dec; 17(1):1-14. PubMed ID: 37749865
[TBL] [Abstract][Full Text] [Related]
10. PORCN promotes hepatocellular carcinogenesis via Wnt/β-catenin-dependent manner.
Wu S; Liu Z; Chen J; Ma T; Wang L; Huang T; Sheng Y; Huang W; Lu C
Transl Cancer Res; 2023 Jul; 12(7):1703-1714. PubMed ID: 37588740
[TBL] [Abstract][Full Text] [Related]
11. Porcupine inhibitor suppresses paracrine Wnt-driven growth of Rnf43;Znrf3-mutant neoplasia.
Koo BK; van Es JH; van den Born M; Clevers H
Proc Natl Acad Sci U S A; 2015 Jun; 112(24):7548-50. PubMed ID: 26023187
[TBL] [Abstract][Full Text] [Related]
12. Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells.
Huels DJ; Bruens L; Hodder MC; Cammareri P; Campbell AD; Ridgway RA; Gay DM; Solar-Abboud M; Faller WJ; Nixon C; Zeiger LB; McLaughlin ME; Morrissey E; Winton DJ; Snippert HJ; van Rheenen J; Sansom OJ
Nat Commun; 2018 Mar; 9(1):1132. PubMed ID: 29556067
[TBL] [Abstract][Full Text] [Related]
13. Cell biology. The unusual case of Porcupine.
Lum L; Clevers H
Science; 2012 Aug; 337(6097):922-3. PubMed ID: 22923569
[TBL] [Abstract][Full Text] [Related]
14. Wnt pathway inhibition with the porcupine inhibitor LGK974 decreases trabecular bone but not fibrosis in a murine model with fibrotic bone.
Lung H; Wentworth KL; Moody T; Zamarioli A; Ram A; Ganesh G; Kang M; Ho S; Hsiao EC
JBMR Plus; 2024 May; 8(5):ziae011. PubMed ID: 38577521
[TBL] [Abstract][Full Text] [Related]
15. R-Spondin chromosome rearrangements drive Wnt-dependent tumour initiation and maintenance in the intestine.
Han T; Schatoff EM; Murphy C; Zafra MP; Wilkinson JE; Elemento O; Dow LE
Nat Commun; 2017 Jul; 8():15945. PubMed ID: 28695896
[TBL] [Abstract][Full Text] [Related]
16. Porcupine inhibitors: Novel and emerging anti-cancer therapeutics targeting the Wnt signaling pathway.
Shah K; Panchal S; Patel B
Pharmacol Res; 2021 May; 167():105532. PubMed ID: 33677106
[TBL] [Abstract][Full Text] [Related]
17. TRIM33 Overexpression Inhibits the Progression of Clear Cell Renal Cell Carcinoma In Vivo and In Vitro.
Xu Y; Wu G; Zhang J; Li J; Ruan N; Zhang J; Zhang Z; Chen Y; Zhang Q; Xia Q
Biomed Res Int; 2020; 2020():8409239. PubMed ID: 32908919
[TBL] [Abstract][Full Text] [Related]
18. Genetic alteration and clinical significance of SUMOylation regulators in multiple cancer types.
Wu G; Xu Y; Ruan N; Li J; Lv Q; Zhang Q; Chen Y; Wang Q; Xia Q; Li Q
J Cancer; 2020; 11(23):6823-6833. PubMed ID: 33123273
[TBL] [Abstract][Full Text] [Related]
19. Mechanisms and inhibition of Porcupine-mediated Wnt acylation.
Liu Y; Qi X; Donnelly L; Elghobashi-Meinhardt N; Long T; Zhou RW; Sun Y; Wang B; Li X
Nature; 2022 Jul; 607(7920):816-822. PubMed ID: 35831507
[TBL] [Abstract][Full Text] [Related]
20. The role of Evi/Wntless in exporting Wnt proteins.
Wolf L; Boutros M
Development; 2023 Feb; 150(3):. PubMed ID: 36763105
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]