239 related articles for article (PubMed ID: 32107312)
1. Kinetic parameters of human aspartate/asparagine-β-hydroxylase suggest that it has a possible function in oxygen sensing.
Brewitz L; Tumber A; Schofield CJ
J Biol Chem; 2020 Jun; 295(23):7826-7838. PubMed ID: 32107312
[TBL] [Abstract][Full Text] [Related]
2. Aspartate/asparagine-β-hydroxylase crystal structures reveal an unexpected epidermal growth factor-like domain substrate disulfide pattern.
Pfeffer I; Brewitz L; Krojer T; Jensen SA; Kochan GT; Kershaw NJ; Hewitson KS; McNeill LA; Kramer H; Münzel M; Hopkinson RJ; Oppermann U; Handford PA; McDonough MA; Schofield CJ
Nat Commun; 2019 Oct; 10(1):4910. PubMed ID: 31659163
[TBL] [Abstract][Full Text] [Related]
3. Aspartate/asparagine-β-hydroxylase: a high-throughput mass spectrometric assay for discovery of small molecule inhibitors.
Brewitz L; Tumber A; Pfeffer I; McDonough MA; Schofield CJ
Sci Rep; 2020 May; 10(1):8650. PubMed ID: 32457455
[TBL] [Abstract][Full Text] [Related]
4. Synthesis of Novel Pyridine-Carboxylates as Small-Molecule Inhibitors of Human Aspartate/Asparagine-β-Hydroxylase.
Brewitz L; Tumber A; Thalhammer A; Salah E; Christensen KE; Schofield CJ
ChemMedChem; 2020 Jul; 15(13):1139-1149. PubMed ID: 32330361
[TBL] [Abstract][Full Text] [Related]
5. Combined proteomic and biochemical analyses redefine the consensus sequence requirement for epidermal growth factor-like domain hydroxylation.
Brewitz L; Onisko BC; Schofield CJ
J Biol Chem; 2022 Aug; 298(8):102129. PubMed ID: 35700824
[TBL] [Abstract][Full Text] [Related]
6. Small-molecule active pharmaceutical ingredients of approved cancer therapeutics inhibit human aspartate/asparagine-β-hydroxylase.
Brewitz L; Tumber A; Zhang X; Schofield CJ
Bioorg Med Chem; 2020 Oct; 28(20):115675. PubMed ID: 33069066
[TBL] [Abstract][Full Text] [Related]
7. Synthesis of 2-oxoglutarate derivatives and their evaluation as cosubstrates and inhibitors of human aspartate/asparagine-β-hydroxylase.
Brewitz L; Nakashima Y; Schofield CJ
Chem Sci; 2020 Dec; 12(4):1327-1342. PubMed ID: 34163896
[TBL] [Abstract][Full Text] [Related]
8. Human Oxygenase Variants Employing a Single Protein Fe
Brasnett A; Pfeffer I; Brewitz L; Chowdhury R; Nakashima Y; Tumber A; McDonough MA; Schofield CJ
Angew Chem Int Ed Engl; 2021 Jun; 60(26):14657-14663. PubMed ID: 33887099
[TBL] [Abstract][Full Text] [Related]
9. Human aspartyl (asparaginyl) hydroxylase. A multifaceted enzyme with broad intra- and extra-cellular activity.
Greve JM; Pinkham AM; Cowan JA
Metallomics; 2021 Aug; 13(8):. PubMed ID: 34283245
[TBL] [Abstract][Full Text] [Related]
10. Fluorinated derivatives of pyridine-2,4-dicarboxylate are potent inhibitors of human 2-oxoglutarate dependent oxygenases.
Brewitz L; Nakashima Y; Tumber A; Salah E; Schofield CJ
J Fluor Chem; 2021 Jul; 247():109804. PubMed ID: 34219804
[TBL] [Abstract][Full Text] [Related]
11. Aspartate β-hydroxylase targeting in castration-resistant prostate cancer modulates the NOTCH/HIF1α/GSK3β crosstalk.
Barboro P; Benelli R; Tosetti F; Costa D; Capaia M; Astigiano S; Venè R; Poggi A; Ferrari N
Carcinogenesis; 2020 Sep; 41(9):1246-1252. PubMed ID: 32525968
[TBL] [Abstract][Full Text] [Related]
12. 2-Oxoglutarate derivatives can selectively enhance or inhibit the activity of human oxygenases.
Nakashima Y; Brewitz L; Tumber A; Salah E; Schofield CJ
Nat Commun; 2021 Nov; 12(1):6478. PubMed ID: 34759269
[TBL] [Abstract][Full Text] [Related]
13. Recent advances in research on aspartate β-hydroxylase (ASPH) in pancreatic cancer: A brief update.
Hou G; Xu B; Bi Y; Wu C; Ru B; Sun B; Bai X
Bosn J Basic Med Sci; 2018 Nov; 18(4):297-304. PubMed ID: 30179586
[TBL] [Abstract][Full Text] [Related]
14. Human Oxygenase Variants Employing a Single Protein Fe
Brasnett A; Pfeffer I; Brewitz L; Chowdhury R; Nakashima Y; Tumber A; McDonough MA; Schofield CJ
Angew Chem Weinheim Bergstr Ger; 2021 Jun; 133(26):14778-14784. PubMed ID: 38505373
[TBL] [Abstract][Full Text] [Related]
15. Aspartate beta-hydroxylase promotes cholangiocarcinoma progression by modulating RB1 phosphorylation.
Huang CK; Iwagami Y; Zou J; Casulli S; Lu S; Nagaoka K; Ji C; Ogawa K; Cao KY; Gao JS; Carlson RI; Wands JR
Cancer Lett; 2018 Aug; 429():1-10. PubMed ID: 29733964
[TBL] [Abstract][Full Text] [Related]
16. Diverse molecular functions of aspartate β‑hydroxylase in cancer (Review).
Zheng W; Wang X; Hu J; Bai B; Zhu H
Oncol Rep; 2020 Dec; 44(6):2364-2372. PubMed ID: 33125119
[TBL] [Abstract][Full Text] [Related]
17. Aspartate β-hydroxylase (ASPH) Accelerates Intrahepatic Cholangiocarcinoma Metastasis
Zou Y; Lin J; Liu J; Zhang F; Yang T; Gong J; Jiang T; Zuo J; Song R; Shen H; Shen F; Li J
Curr Protein Pept Sci; 2023; 24(5):436-446. PubMed ID: 37132101
[TBL] [Abstract][Full Text] [Related]
18. Unusual catalytic strategy by non-heme Fe(ii)/2-oxoglutarate-dependent aspartyl hydroxylase AspH.
Krishnan A; Waheed SO; Varghese A; Cherilakkudy FH; Schofield CJ; Karabencheva-Christova TG
Chem Sci; 2024 Mar; 15(10):3466-3484. PubMed ID: 38455014
[TBL] [Abstract][Full Text] [Related]
19. Whole-exome sequencing identified a novel homozygous ASPH frameshift variant causing Traboulsi syndrome in a Chinese family.
Lei C; Guo T; Ding S; Liao L; Peng H; Tan Z; Luo H
Mol Genet Genomic Med; 2021 Jan; 9(1):e1553. PubMed ID: 33217155
[TBL] [Abstract][Full Text] [Related]
20. Aspartate β-hydroxylase promotes pancreatic ductal adenocarcinoma metastasis through activation of SRC signaling pathway.
Ogawa K; Lin Q; Li L; Bai X; Chen X; Chen H; Kong R; Wang Y; Zhu H; He F; Xu Q; Liu L; Li M; Zhang S; Nagaoka K; Carlson R; Safran H; Charpentier K; Sun B; Wands J; Dong X
J Hematol Oncol; 2019 Dec; 12(1):144. PubMed ID: 31888763
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]