BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

117 related articles for article (PubMed ID: 32109341)

  • 1. Identification and characterization of alternative STK39 transcripts within human and mouse kidneys reveals species-specific regulation of blood pressure.
    Mercado CJ; Wang X; Grimm PR; Welling PA; Chang YC
    Physiol Rep; 2020 Feb; 8(4):e14379. PubMed ID: 32109341
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation of NKCC2 activity by inhibitory SPAK isoforms: KS-SPAK is a more potent inhibitor than SPAK2.
    Park HJ; Curry JN; McCormick JA
    Am J Physiol Renal Physiol; 2013 Dec; 305(12):F1687-96. PubMed ID: 24133122
    [TBL] [Abstract][Full Text] [Related]  

  • 3. STE20/SPS1-related proline/alanine-rich kinase (SPAK) is critical for sodium reabsorption in isolated, perfused thick ascending limb.
    Cheng CJ; Yoon J; Baum M; Huang CL
    Am J Physiol Renal Physiol; 2015 Mar; 308(5):F437-43. PubMed ID: 25477470
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SPAK-knockout mice manifest Gitelman syndrome and impaired vasoconstriction.
    Yang SS; Lo YF; Wu CC; Lin SW; Yeh CJ; Chu P; Sytwu HK; Uchida S; Sasaki S; Lin SH
    J Am Soc Nephrol; 2010 Nov; 21(11):1868-77. PubMed ID: 20813865
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Generation of Hypertension-Associated STK39 Polymorphism Knockin Cell Lines With the Clustered Regularly Interspaced Short Palindromic Repeats/Cas9 System.
    Mandai S; Mori T; Sohara E; Rai T; Uchida S
    Hypertension; 2015 Dec; 66(6):1199-206. PubMed ID: 26416847
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel mechanisms of Na+ retention in obesity: phosphorylation of NKCC2 and regulation of SPAK/OSR1 by AMPK.
    Davies M; Fraser SA; Galic S; Choy SW; Katerelos M; Gleich K; Kemp BE; Mount PF; Power DA
    Am J Physiol Renal Physiol; 2014 Jul; 307(1):F96-F106. PubMed ID: 24808538
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Critical role of the SPAK protein kinase CCT domain in controlling blood pressure.
    Zhang J; Siew K; Macartney T; O'Shaughnessy KM; Alessi DR
    Hum Mol Genet; 2015 Aug; 24(16):4545-58. PubMed ID: 25994507
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SPAK and WNK kinases: a new target for blood pressure treatment?
    Glover M; O'shaughnessy KM
    Curr Opin Nephrol Hypertens; 2011 Jan; 20(1):16-22. PubMed ID: 21088576
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SPAK and OSR1 play essential roles in potassium homeostasis through actions on the distal convoluted tubule.
    Ferdaus MZ; Barber KW; López-Cayuqueo KI; Terker AS; Argaiz ER; Gassaway BM; Chambrey R; Gamba G; Rinehart J; McCormick JA
    J Physiol; 2016 Sep; 594(17):4945-66. PubMed ID: 27068441
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Potassium depletion stimulates Na-Cl cotransporter
    Ishizawa K; Xu N; Loffing J; Lifton RP; Fujita T; Uchida S; Shibata S
    Biochem Biophys Res Commun; 2016 Nov; 480(4):745-751. PubMed ID: 27942049
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular insights from dysregulation of the thiazide-sensitive WNK/SPAK/NCC pathway in the kidney: Gordon syndrome and thiazide-induced hyponatraemia.
    Glover M; O'Shaughnessy KM
    Clin Exp Pharmacol Physiol; 2013 Dec; 40(12):876-84. PubMed ID: 23683032
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pharmacological targeting of SPAK kinase in disorders of impaired epithelial transport.
    Zhang J; Karimy JK; Delpire E; Kahle KT
    Expert Opin Ther Targets; 2017 Aug; 21(8):795-804. PubMed ID: 28679296
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hypertension, dietary salt intake, and the role of the thiazide-sensitive sodium chloride transporter NCCT.
    Glover M; Zuber AM; O'Shaughnessy KM
    Cardiovasc Ther; 2011 Feb; 29(1):68-76. PubMed ID: 21167012
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of Novel SPAK Inhibitors That Block WNK Kinase Signaling to Cation Chloride Transporters.
    Kikuchi E; Mori T; Zeniya M; Isobe K; Ishigami-Yuasa M; Fujii S; Kagechika H; Ishihara T; Mizushima T; Sasaki S; Sohara E; Rai T; Uchida S
    J Am Soc Nephrol; 2015 Jul; 26(7):1525-36. PubMed ID: 25377078
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cotransporters, WNKs and hypertension: an update.
    Flatman PW
    Curr Opin Nephrol Hypertens; 2008 Mar; 17(2):186-92. PubMed ID: 18277153
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inactivation of SPAK kinase reduces body weight gain in mice fed a high-fat diet by improving energy expenditure and insulin sensitivity.
    Torre-Villalvazo I; Cervantes-Pérez LG; Noriega LG; Jiménez JV; Uribe N; Chávez-Canales M; Tovar-Palacio C; Marfil-Garza BA; Torres N; Bobadilla NA; Tovar AR; Gamba G
    Am J Physiol Endocrinol Metab; 2018 Jan; 314(1):E53-E65. PubMed ID: 29066461
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases.
    Vitari AC; Deak M; Morrice NA; Alessi DR
    Biochem J; 2005 Oct; 391(Pt 1):17-24. PubMed ID: 16083423
    [TBL] [Abstract][Full Text] [Related]  

  • 18. From the Cover: Whole-genome association study identifies STK39 as a hypertension susceptibility gene.
    Wang Y; O'Connell JR; McArdle PF; Wade JB; Dorff SE; Shah SJ; Shi X; Pan L; Rampersaud E; Shen H; Kim JD; Subramanya AR; Steinle NI; Parsa A; Ober CC; Welling PA; Chakravarti A; Weder AB; Cooper RS; Mitchell BD; Shuldiner AR; Chang YP
    Proc Natl Acad Sci U S A; 2009 Jan; 106(1):226-31. PubMed ID: 19114657
    [TBL] [Abstract][Full Text] [Related]  

  • 19. WNK4 is indispensable for the pathogenesis of pseudohypoaldosteronism type II caused by mutant KLHL3.
    Susa K; Sohara E; Takahashi D; Okado T; Rai T; Uchida S
    Biochem Biophys Res Commun; 2017 Sep; 491(3):727-732. PubMed ID: 28743496
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Chronic Metabolic Acidosis Activates Renal Tubular Sodium Chloride Cotransporter through Angiotension II-dependent WNK4-SPAK Phosphorylation Pathway.
    Fang YW; Yang SS; Cheng CJ; Tseng MH; Hsu HM; Lin SH
    Sci Rep; 2016 Jan; 6():18360. PubMed ID: 26728390
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.