BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1380 related articles for article (PubMed ID: 32109412)

  • 1. Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
    Wang K; Sun Q; Zhong X; Zeng M; Zeng H; Shi X; Li Z; Wang Y; Zhao Q; Shao F; Ding J
    Cell; 2020 Mar; 180(5):941-955.e20. PubMed ID: 32109412
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Live-cell visualization of gasdermin D-driven pyroptotic cell death.
    Rathkey JK; Benson BL; Chirieleison SM; Yang J; Xiao TS; Dubyak GR; Huang AY; Abbott DW
    J Biol Chem; 2017 Sep; 292(35):14649-14658. PubMed ID: 28726636
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
    Shi J; Zhao Y; Wang K; Shi X; Wang Y; Huang H; Zhuang Y; Cai T; Wang F; Shao F
    Nature; 2015 Oct; 526(7575):660-5. PubMed ID: 26375003
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage.
    Liu Z; Wang C; Yang J; Chen Y; Zhou B; Abbott DW; Xiao TS
    Immunity; 2020 Jul; 53(1):106-114.e5. PubMed ID: 32553275
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor.
    Yang J; Liu Z; Wang C; Yang R; Rathkey JK; Pinkard OW; Shi W; Chen Y; Dubyak GR; Abbott DW; Xiao TS
    Proc Natl Acad Sci U S A; 2018 Jun; 115(26):6792-6797. PubMed ID: 29891674
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of AIM2 inflammasome activation alleviates GSDMD-induced pyroptosis in early brain injury after subarachnoid haemorrhage.
    Yuan B; Zhou XM; You ZQ; Xu WD; Fan JM; Chen SJ; Han YL; Wu Q; Zhang X
    Cell Death Dis; 2020 Jan; 11(1):76. PubMed ID: 32001670
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Caspase-1 cleaves Bid to release mitochondrial SMAC and drive secondary necrosis in the absence of GSDMD.
    Heilig R; Dilucca M; Boucher D; Chen KW; Hancz D; Demarco B; Shkarina K; Broz P
    Life Sci Alliance; 2020 Jun; 3(6):. PubMed ID: 32345661
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Snapshot of a Deadly Embrace: The Caspase-1-GSDMD Interface.
    Vande Walle L; Lamkanfi M
    Immunity; 2020 Jul; 53(1):6-8. PubMed ID: 32668229
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Emerging insights into molecular mechanisms underlying pyroptosis and functions of inflammasomes in diseases.
    Lu F; Lan Z; Xin Z; He C; Guo Z; Xia X; Hu T
    J Cell Physiol; 2020 Apr; 235(4):3207-3221. PubMed ID: 31621910
    [TBL] [Abstract][Full Text] [Related]  

  • 10. FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation.
    Hu JJ; Liu X; Xia S; Zhang Z; Zhang Y; Zhao J; Ruan J; Luo X; Lou X; Bai Y; Wang J; Hollingsworth LR; Magupalli VG; Zhao L; Luo HR; Kim J; Lieberman J; Wu H
    Nat Immunol; 2020 Jul; 21(7):736-745. PubMed ID: 32367036
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion.
    He WT; Wan H; Hu L; Chen P; Wang X; Huang Z; Yang ZH; Zhong CQ; Han J
    Cell Res; 2015 Dec; 25(12):1285-98. PubMed ID: 26611636
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The colonic pathogen Entamoeba histolytica activates caspase-4/1 that cleaves the pore-forming protein gasdermin D to regulate IL-1β secretion.
    Wang S; Moreau F; Chadee K
    PLoS Pathog; 2022 Mar; 18(3):e1010415. PubMed ID: 35303042
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Gasdermin D serves as a key executioner of pyroptosis in experimental cerebral ischemia and reperfusion model both in vivo and in vitro.
    Zhang D; Qian J; Zhang P; Li H; Shen H; Li X; Chen G
    J Neurosci Res; 2019 Jun; 97(6):645-660. PubMed ID: 30600840
    [TBL] [Abstract][Full Text] [Related]  

  • 14. GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death.
    Sborgi L; Rühl S; Mulvihill E; Pipercevic J; Heilig R; Stahlberg H; Farady CJ; Müller DJ; Broz P; Hiller S
    EMBO J; 2016 Aug; 35(16):1766-78. PubMed ID: 27418190
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Gasdermin D Cleavage Assay Following Inflammasome Activation.
    Kamajaya LJ; Boucher D
    Methods Mol Biol; 2022; 2459():39-49. PubMed ID: 35212952
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gasdermin D Protects from Melioidosis through Pyroptosis and Direct Killing of Bacteria.
    Wang J; Deobald K; Re F
    J Immunol; 2019 Jun; 202(12):3468-3473. PubMed ID: 31036765
    [TBL] [Abstract][Full Text] [Related]  

  • 17. IRF2 transcriptionally induces
    Kayagaki N; Lee BL; Stowe IB; Kornfeld OS; O'Rourke K; Mirrashidi KM; Haley B; Watanabe C; Roose-Girma M; Modrusan Z; Kummerfeld S; Reja R; Zhang Y; Cho V; Andrews TD; Morris LX; Goodnow CC; Bertram EM; Dixit VM
    Sci Signal; 2019 May; 12(582):. PubMed ID: 31113851
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An Apoptotic Caspase Network Safeguards Cell Death Induction in Pyroptotic Macrophages.
    de Vasconcelos NM; Van Opdenbosch N; Van Gorp H; Martín-Pérez R; Zecchin A; Vandenabeele P; Lamkanfi M
    Cell Rep; 2020 Jul; 32(4):107959. PubMed ID: 32726624
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cigarette smoke promotes inflammasome-independent activation of caspase-1 and -4 leading to gasdermin D cleavage in human macrophages.
    Buscetta M; Cristaldi M; Cimino M; La Mensa A; Dino P; Bucchieri F; Rappa F; Amato S; Aronica TS; Pace E; Bertani A; Cipollina C
    FASEB J; 2022 Sep; 36(9):e22525. PubMed ID: 36004615
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Monitoring gasdermin pore formation in vitro.
    Xia S; Ruan J; Wu H
    Methods Enzymol; 2019; 625():95-107. PubMed ID: 31455540
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 69.