These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Intestinal Stem Cell Niche Defects Result in Impaired 3D Organoid Formation in Mouse Models of Crohn's Disease-like Ileitis. Buttó LF; Pelletier A; More SK; Zhao N; Osme A; Hager CL; Ghannoum MA; Sekaly RP; Cominelli F; Dave M Stem Cell Reports; 2020 Aug; 15(2):389-407. PubMed ID: 32679063 [TBL] [Abstract][Full Text] [Related]
3. Azathioprine promotes intestinal epithelial cell differentiation into Paneth cells and alleviates ileal Crohn's disease severity. Ragab M; Schlichting H; Hicken M; Mester P; Hirose M; Almeida LN; Christiansen L; Ibrahim S; Tews HC; Divanovic S; Sina C; Derer S Sci Rep; 2024 Jun; 14(1):12879. PubMed ID: 38839896 [TBL] [Abstract][Full Text] [Related]
4. Mitochondrial dysfunction during loss of prohibitin 1 triggers Paneth cell defects and ileitis. Jackson DN; Panopoulos M; Neumann WL; Turner K; Cantarel BL; Thompson-Snipes L; Dassopoulos T; Feagins LA; Souza RF; Mills JC; Blumberg RS; Venuprasad K; Thompson WE; Theiss AL Gut; 2020 Nov; 69(11):1928-1938. PubMed ID: 32111635 [TBL] [Abstract][Full Text] [Related]
5. Interferon Lambda Promotes Paneth Cell Death Via STAT1 Signaling in Mice and Is Increased in Inflamed Ileal Tissues of Patients With Crohn's Disease. Günther C; Ruder B; Stolzer I; Dorner H; He GW; Chiriac MT; Aden K; Strigli A; Bittel M; Zeissig S; Rosenstiel P; Atreya R; Neurath MF; Wirtz S; Becker C Gastroenterology; 2019 Nov; 157(5):1310-1322.e13. PubMed ID: 31352002 [TBL] [Abstract][Full Text] [Related]
6. Control of Paneth cell function by HuR regulates gut mucosal growth by altering stem cell activity. Xiao L; Warner B; Mallard CG; Chung HK; Shetty A; Brantner CA; Rao JN; Yochum GS; Koltun WA; To KB; Turner DJ; Gorospe M; Wang JY Life Sci Alliance; 2023 Nov; 6(11):. PubMed ID: 37696579 [TBL] [Abstract][Full Text] [Related]
7. The ErbB3 receptor tyrosine kinase negatively regulates Paneth cells by PI3K-dependent suppression of Atoh1. Almohazey D; Lo YH; Vossler CV; Simmons AJ; Hsieh JJ; Bucar EB; Schumacher MA; Hamilton KE; Lau KS; Shroyer NF; Frey MR Cell Death Differ; 2017 May; 24(5):855-865. PubMed ID: 28304405 [TBL] [Abstract][Full Text] [Related]
8. Dysbiotic gut microbiota causes transmissible Crohn's disease-like ileitis independent of failure in antimicrobial defence. Schaubeck M; Clavel T; Calasan J; Lagkouvardos I; Haange SB; Jehmlich N; Basic M; Dupont A; Hornef M; von Bergen M; Bleich A; Haller D Gut; 2016 Feb; 65(2):225-37. PubMed ID: 25887379 [TBL] [Abstract][Full Text] [Related]
9. Depletion of Intestinal Stem Cell Niche Factors Contributes to the Alteration of Epithelial Differentiation in SAMP1/YitFcsJ Mice With Crohn Disease-Like Ileitis. Lee C; Hong SN; Kim ER; Chang DK; Kim YH Inflamm Bowel Dis; 2021 Apr; 27(5):667-676. PubMed ID: 33274375 [TBL] [Abstract][Full Text] [Related]
11. Interplay between metabolic identities in the intestinal crypt supports stem cell function. Rodríguez-Colman MJ; Schewe M; Meerlo M; Stigter E; Gerrits J; Pras-Raves M; Sacchetti A; Hornsveld M; Oost KC; Snippert HJ; Verhoeven-Duif N; Fodde R; Burgering BM Nature; 2017 Mar; 543(7645):424-427. PubMed ID: 28273069 [TBL] [Abstract][Full Text] [Related]
12. Interplay of gut microbiota and host epithelial mitochondrial dysfunction is necessary for the development of spontaneous intestinal inflammation in mice. Alula KM; Dowdell AS; LeBere B; Lee JS; Levens CL; Kuhn KA; Kaipparettu BA; Thompson WE; Blumberg RS; Colgan SP; Theiss AL Microbiome; 2023 Nov; 11(1):256. PubMed ID: 37978573 [TBL] [Abstract][Full Text] [Related]
13. Targeting Mitochondrial Damage as a Therapeutic for Ileal Crohn's Disease. Alula KM; Jackson DN; Smith AD; Kim DS; Turner K; Odstrcil E; Kaipparettu BA; Dassopoulos T; Venuprasad K; Feagins LA; Theiss AL Cells; 2021 May; 10(6):. PubMed ID: 34072441 [TBL] [Abstract][Full Text] [Related]
14. Single cell analysis of Crohn's disease patient-derived small intestinal organoids reveals disease activity-dependent modification of stem cell properties. Suzuki K; Murano T; Shimizu H; Ito G; Nakata T; Fujii S; Ishibashi F; Kawamoto A; Anzai S; Kuno R; Kuwabara K; Takahashi J; Hama M; Nagata S; Hiraguri Y; Takenaka K; Yui S; Tsuchiya K; Nakamura T; Ohtsuka K; Watanabe M; Okamoto R J Gastroenterol; 2018 Sep; 53(9):1035-1047. PubMed ID: 29374777 [TBL] [Abstract][Full Text] [Related]
15. Paneth cells mediated the response of intestinal stem cells at the early stage of intestinal inflammation in the chicken. Yu L; Xie X; Jiang K; Hong Y; Zhou Z; Mi Y; Zhang C; Li J Poult Sci; 2021 Feb; 100(2):615-622. PubMed ID: 33518114 [TBL] [Abstract][Full Text] [Related]
16. Diet prevents the expansion of segmented filamentous bacteria and ileo-colonic inflammation in a model of Crohn's disease. Metwaly A; Jovic J; Waldschmitt N; Khaloian S; Heimes H; Häcker D; Ahmed M; Hammoudi N; Le Bourhis L; Mayorgas A; Siebert K; Basic M; Schwerd T; Allez M; Panes J; Salas A; Bleich A; Zeissig S; Schnupf P; Cominelli F; Haller D Microbiome; 2023 Mar; 11(1):66. PubMed ID: 37004103 [TBL] [Abstract][Full Text] [Related]
17. The Organoid Reconstitution Assay (ORA) for the Functional Analysis of Intestinal Stem and Niche Cells. Schewe M; Sacchetti A; Schmitt M; Fodde R J Vis Exp; 2017 Nov; (129):. PubMed ID: 29286377 [TBL] [Abstract][Full Text] [Related]
18. The phosphatase PRL-3 affects intestinal homeostasis by altering the crypt cell composition. Rubio T; Weyershaeuser J; Montero MG; Hoffmann A; Lujan P; Jechlinger M; Sotillo R; Köhn M J Mol Med (Berl); 2021 Oct; 99(10):1413-1426. PubMed ID: 34129057 [TBL] [Abstract][Full Text] [Related]
19. TNFα Induces LGR5+ Stem Cell Dysfunction In Patients With Crohn's Disease. Lee C; An M; Joung JG; Park WY; Chang DK; Kim YH; Hong SN Cell Mol Gastroenterol Hepatol; 2022; 13(3):789-808. PubMed ID: 34700029 [TBL] [Abstract][Full Text] [Related]
20. Paneth cell-derived iNOS is required to maintain homeostasis in the intestinal stem cell niche. Huang L; Xu Z; Lei X; Huang Y; Tu S; Xu L; Xia J; Liu D J Transl Med; 2023 Nov; 21(1):852. PubMed ID: 38007452 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]