356 related articles for article (PubMed ID: 32112900)
1. Pik3ca mutations significantly enhance the growth of SHH medulloblastoma and lead to metastatic tumour growth in a novel mouse model.
Niesen J; Ohli J; Sedlacik J; Dührsen L; Hellwig M; Spohn M; Holsten T; Schüller U
Cancer Lett; 2020 May; 477():10-18. PubMed ID: 32112900
[TBL] [Abstract][Full Text] [Related]
2. Lateral cerebellum is preferentially sensitive to high sonic hedgehog signaling and medulloblastoma formation.
Tan IL; Wojcinski A; Rallapalli H; Lao Z; Sanghrajka RM; Stephen D; Volkova E; Korshunov A; Remke M; Taylor MD; Turnbull DH; Joyner AL
Proc Natl Acad Sci U S A; 2018 Mar; 115(13):3392-3397. PubMed ID: 29531057
[TBL] [Abstract][Full Text] [Related]
3. Transcriptional repressor REST drives lineage stage-specific chromatin compaction at
Dobson THW; Tao RH; Swaminathan J; Maegawa S; Shaik S; Bravo-Alegria J; Sharma A; Kennis B; Yang Y; Callegari K; Haltom AR; Taylor P; Kogiso M; Qi L; Khatua S; Goldman S; Lulla RR; Fangusaro J; MacDonald TJ; Li XN; Hawkins C; Rajaram V; Gopalakrishnan V
Sci Signal; 2019 Jan; 12(565):. PubMed ID: 30670636
[TBL] [Abstract][Full Text] [Related]
4. Hedgehog pathway permissive conditions allow generation of immortal cell lines from granule cells derived from cancerous and non-cancerous cerebellum.
Heil C
Open Biol; 2019 Jan; 9(1):180145. PubMed ID: 30958113
[TBL] [Abstract][Full Text] [Related]
5. Genetic ablation of Gpr37l1 delays tumor occurrence in Ptch1
Di Pietro C; La Sala G; Matteoni R; Marazziti D; Tocchini-Valentini GP
Exp Neurol; 2019 Feb; 312():33-42. PubMed ID: 30452905
[TBL] [Abstract][Full Text] [Related]
6. Sonic Hedgehog Medulloblastoma Cancer Stem Cells Mirnome and Transcriptome Highlight Novel Functional Networks.
Po A; Abballe L; Sabato C; Gianno F; Chiacchiarini M; Catanzaro G; De Smaele E; Giangaspero F; Ferretti E; Miele E; Besharat ZM
Int J Mol Sci; 2018 Aug; 19(8):. PubMed ID: 30096798
[TBL] [Abstract][Full Text] [Related]
7. Functional loss of a noncanonical BCOR-PRC1.1 complex accelerates SHH-driven medulloblastoma formation.
Kutscher LM; Okonechnikov K; Batora NV; Clark J; Silva PBG; Vouri M; van Rijn S; Sieber L; Statz B; Gearhart MD; Shiraishi R; Mack N; Orr BA; Korshunov A; Gudenas BL; Smith KS; Mercier AL; Ayrault O; Hoshino M; Kool M; von Hoff K; Graf N; Fleischhack G; Bardwell VJ; Pfister SM; Northcott PA; Kawauchi D
Genes Dev; 2020 Sep; 34(17-18):1161-1176. PubMed ID: 32820036
[TBL] [Abstract][Full Text] [Related]
8. Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition.
Kool M; Jones DT; Jäger N; Northcott PA; Pugh TJ; Hovestadt V; Piro RM; Esparza LA; Markant SL; Remke M; Milde T; Bourdeaut F; Ryzhova M; Sturm D; Pfaff E; Stark S; Hutter S; Seker-Cin H; Johann P; Bender S; Schmidt C; Rausch T; Shih D; Reimand J; Sieber L; Wittmann A; Linke L; Witt H; Weber UD; Zapatka M; König R; Beroukhim R; Bergthold G; van Sluis P; Volckmann R; Koster J; Versteeg R; Schmidt S; Wolf S; Lawerenz C; Bartholomae CC; von Kalle C; Unterberg A; Herold-Mende C; Hofer S; Kulozik AE; von Deimling A; Scheurlen W; Felsberg J; Reifenberger G; Hasselblatt M; Crawford JR; Grant GA; Jabado N; Perry A; Cowdrey C; Croul S; Zadeh G; Korbel JO; Doz F; Delattre O; Bader GD; McCabe MG; Collins VP; Kieran MW; Cho YJ; Pomeroy SL; Witt O; Brors B; Taylor MD; Schüller U; Korshunov A; Eils R; Wechsler-Reya RJ; Lichter P; Pfister SM;
Cancer Cell; 2014 Mar; 25(3):393-405. PubMed ID: 24651015
[TBL] [Abstract][Full Text] [Related]
9. Preponderance of sonic hedgehog pathway activation characterizes adult medulloblastoma.
Al-Halabi H; Nantel A; Klekner A; Guiot MC; Albrecht S; Hauser P; Garami M; Bognar L; Kavan P; Gerges N; Shirinian M; Roberge D; Muanza T; Jabado N
Acta Neuropathol; 2011 Feb; 121(2):229-39. PubMed ID: 21107850
[TBL] [Abstract][Full Text] [Related]
10. PTCH1-mutant human cerebellar organoids exhibit altered neural development and recapitulate early medulloblastoma tumorigenesis.
van Essen MJ; Apsley EJ; Riepsaame J; Xu R; Northcott PA; Cowley SA; Jacob J; Becker EBE
Dis Model Mech; 2024 Feb; 17(2):. PubMed ID: 38411252
[TBL] [Abstract][Full Text] [Related]
11. Disruption of the ciliary GTPase Arl13b suppresses Sonic hedgehog overactivation and inhibits medulloblastoma formation.
Bay SN; Long AB; Caspary T
Proc Natl Acad Sci U S A; 2018 Feb; 115(7):1570-1575. PubMed ID: 29378965
[TBL] [Abstract][Full Text] [Related]
12. Ex vivo miRNome analysis in Ptch1+/- cerebellum granule cells reveals a subset of miRNAs involved in radiation-induced medulloblastoma.
Tanno B; Babini G; Leonardi S; Giardullo P; De Stefano I; Pasquali E; Ottolenghi A; Atkinson MJ; Saran A; Mancuso M
Oncotarget; 2016 Oct; 7(42):68253-68269. PubMed ID: 27626168
[TBL] [Abstract][Full Text] [Related]
13. Truncated BRPF1 Cooperates with Smoothened to Promote Adult Shh Medulloblastoma.
Aiello G; Ballabio C; Ruggeri R; Fagnocchi L; Anderle M; Morassut I; Caron D; Garilli F; Gianno F; Giangaspero F; Piazza S; Romanel A; Zippo A; Tiberi L
Cell Rep; 2019 Dec; 29(12):4036-4052.e10. PubMed ID: 31851932
[TBL] [Abstract][Full Text] [Related]
14. SHH desmoplastic/nodular medulloblastoma and Gorlin syndrome in the setting of Down syndrome: case report, molecular profiling, and review of the literature.
Mangum R; Varga E; Boué DR; Capper D; Benesch M; Leonard J; Osorio DS; Pierson CR; Zumberge N; Sahm F; Schrimpf D; Pfister SM; Finlay JL
Childs Nerv Syst; 2016 Dec; 32(12):2439-2446. PubMed ID: 27444290
[TBL] [Abstract][Full Text] [Related]
15. CAT3, a novel agent for medulloblastoma and glioblastoma treatment, inhibits tumor growth by disrupting the Hedgehog signaling pathway.
Chen J; Lv H; Hu J; Ji M; Xue N; Li C; Ma S; Zhou Q; Lin B; Li Y; Yu S; Chen X
Cancer Lett; 2016 Oct; 381(2):391-403. PubMed ID: 27495899
[TBL] [Abstract][Full Text] [Related]
16. Patched1 deletion increases N-Myc protein stability as a mechanism of medulloblastoma initiation and progression.
Thomas WD; Chen J; Gao YR; Cheung B; Koach J; Sekyere E; Norris MD; Haber M; Ellis T; Wainwright B; Marshall GM
Oncogene; 2009 Apr; 28(13):1605-15. PubMed ID: 19234491
[TBL] [Abstract][Full Text] [Related]
17. A gene dosage-dependent effect unveils NBS1 as both a haploinsufficient tumour suppressor and an essential gene for SHH-medulloblastoma.
Petroni M; Fabretti F; Di Giulio S; Nicolis di Robilant V; La Monica V; Moretti M; Belardinilli F; Bufalieri F; Coppa A; Paci P; Corsi A; De Smaele E; Coni S; Canettieri G; Di Marcotullio L; Wang ZQ; Giannini G
Neuropathol Appl Neurobiol; 2022 Oct; 48(6):e12837. PubMed ID: 35839783
[TBL] [Abstract][Full Text] [Related]
18. Astrocytes Promote Medulloblastoma Progression through Hedgehog Secretion.
Liu Y; Yuelling LW; Wang Y; Du F; Gordon RE; O'Brien JA; Ng JMY; Robins S; Lee EH; Liu H; Curran T; Yang ZJ
Cancer Res; 2017 Dec; 77(23):6692-6703. PubMed ID: 28986380
[TBL] [Abstract][Full Text] [Related]
19. LOXL1-AS1 contributes to metastasis in sonic-hedgehog medulloblastoma by promoting cancer stem-like phenotypes.
Do AD; Wu KS; Chu SS; Giang LH; Lin YL; Chang CC; Wong TT; Hsieh CL; Sung SY
J Exp Clin Cancer Res; 2024 Apr; 43(1):130. PubMed ID: 38689348
[TBL] [Abstract][Full Text] [Related]
20. Targeted treatment for sonic hedgehog-dependent medulloblastoma.
Kieran MW
Neuro Oncol; 2014 Aug; 16(8):1037-47. PubMed ID: 24951114
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
