BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 32141297)

  • 1. Structure-Activity Relationship Studies of Tetrahydroquinolone Free Fatty Acid Receptor 3 Modulators.
    Ulven ER; Quon T; Sergeev E; Barki N; Brvar M; Hudson BD; Dutta P; Hansen AH; Bielefeldt LØ; Tobin AB; McKenzie CJ; Milligan G; Ulven T
    J Med Chem; 2020 Apr; 63(7):3577-3595. PubMed ID: 32141297
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-activity relationship studies of tetrahydroquinolone derivatives as GPR41 modulators.
    Inuki S; Miyamoto J; Hashimoto N; Shimizu H; Tabuchi H; Kawai A; Greiner LC; Kimura I; Ohno H
    Bioorg Med Chem Lett; 2024 Jul; 107():129758. PubMed ID: 38641152
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ligands at the Free Fatty Acid Receptors 2/3 (GPR43/GPR41).
    Milligan G; Bolognini D; Sergeev E
    Handb Exp Pharmacol; 2017; 236():17-32. PubMed ID: 27757758
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Complex pharmacology of novel allosteric free fatty acid 3 receptor ligands.
    Hudson BD; Christiansen E; Murdoch H; Jenkins L; Hansen AH; Madsen O; Ulven T; Milligan G
    Mol Pharmacol; 2014 Aug; 86(2):200-10. PubMed ID: 24870406
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Agonism and allosterism: the pharmacology of the free fatty acid receptors FFA2 and FFA3.
    Milligan G; Stoddart LA; Smith NJ
    Br J Pharmacol; 2009 Sep; 158(1):146-53. PubMed ID: 19719777
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Free fatty acid receptors: structural models and elucidation of ligand binding interactions.
    Tikhonova IG; Poerio E
    BMC Struct Biol; 2015 Sep; 15():16. PubMed ID: 26346819
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Short-chain free fatty acid receptors FFA2/GPR43 and FFA3/GPR41 as new potential therapeutic targets.
    Ulven T
    Front Endocrinol (Lausanne); 2012; 3():111. PubMed ID: 23060857
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Chemogenetics defines a short-chain fatty acid receptor gut-brain axis.
    Barki N; Bolognini D; Börjesson U; Jenkins L; Riddell J; Hughes DI; Ulven T; Hudson BD; Ulven ER; Dekker N; Tobin AB; Milligan G
    Elife; 2022 Mar; 11():. PubMed ID: 35229717
    [TBL] [Abstract][Full Text] [Related]  

  • 9. New positive allosteric modulators of the metabotropic glutamate receptor 2 (mGluR2): identification and synthesis of N-propyl-8-chloro-6-substituted isoquinolones.
    Trabanco AA; Duvey G; Cid JM; Macdonald GJ; Cluzeau P; Nhem V; Furnari R; Behaj N; Poulain G; Finn T; Lavreysen H; Poli S; Raux A; Thollon Y; Poirier N; D'Addona D; Andrés JI; Lutjens R; Le Poul E; Imogai H; Rocher JP
    Bioorg Med Chem Lett; 2011 Feb; 21(3):971-6. PubMed ID: 21232953
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Free fatty acid receptor 3 is a key target of short chain fatty acid. What is the impact on the sympathetic nervous system?
    López Soto EJ; Gambino LO; Mustafá ER
    Channels (Austin); 2014; 8(3):169-71. PubMed ID: 24762451
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3.
    Schmidt J; Smith NJ; Christiansen E; Tikhonova IG; Grundmann M; Hudson BD; Ward RJ; Drewke C; Milligan G; Kostenis E; Ulven T
    J Biol Chem; 2011 Mar; 286(12):10628-40. PubMed ID: 21220428
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia.
    Nøhr MK; Egerod KL; Christiansen SH; Gille A; Offermanns S; Schwartz TW; Møller M
    Neuroscience; 2015 Apr; 290():126-37. PubMed ID: 25637492
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification and functional characterization of allosteric agonists for the G protein-coupled receptor FFA2.
    Lee T; Schwandner R; Swaminath G; Weiszmann J; Cardozo M; Greenberg J; Jaeckel P; Ge H; Wang Y; Jiao X; Liu J; Kayser F; Tian H; Li Y
    Mol Pharmacol; 2008 Dec; 74(6):1599-609. PubMed ID: 18818303
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Free fatty acid receptor 3 differentially contributes to β-cell compensation under high-fat diet and streptozotocin stress.
    Priyadarshini M; Cole C; Oroskar G; Ludvik AE; Wicksteed B; He C; Layden BT
    Am J Physiol Regul Integr Comp Physiol; 2020 Apr; 318(4):R691-R700. PubMed ID: 32073900
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Application of GPCR Structures for Modelling of Free Fatty Acid Receptors.
    Tikhonova IG
    Handb Exp Pharmacol; 2017; 236():57-77. PubMed ID: 27757764
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Short-chain fatty acid mitigates adenine-induced chronic kidney disease via FFA2 and FFA3 pathways.
    Mikami D; Kobayashi M; Uwada J; Yazawa T; Kamiyama K; Nishimori K; Nishikawa Y; Nishikawa S; Yokoi S; Kimura H; Kimura I; Taniguchi T; Iwano M
    Biochim Biophys Acta Mol Cell Biol Lipids; 2020 Jun; 1865(6):158666. PubMed ID: 32061840
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The first synthetic agonists of FFA2: Discovery and SAR of phenylacetamides as allosteric modulators.
    Wang Y; Jiao X; Kayser F; Liu J; Wang Z; Wanska M; Greenberg J; Weiszmann J; Ge H; Tian H; Wong S; Schwandner R; Lee T; Li Y
    Bioorg Med Chem Lett; 2010 Jan; 20(2):493-8. PubMed ID: 20005104
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, structure-activity relationships and biological evaluation of 7-phenyl-pyrroloquinolinone 3-amide derivatives as potent antimitotic agents.
    Carta D; Bortolozzi R; Sturlese M; Salmaso V; Hamel E; Basso G; Calderan L; Quintieri L; Moro S; Viola G; Ferlin MG
    Eur J Med Chem; 2017 Feb; 127():643-660. PubMed ID: 27823884
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design of 4-Oxo-1-aryl-1,4-dihydroquinoline-3-carboxamides as Selective Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 2.
    Felts AS; Rodriguez AL; Smith KA; Engers JL; Morrison RD; Byers FW; Blobaum AL; Locuson CW; Chang S; Venable DF; Niswender CM; Daniels JS; Conn PJ; Lindsley CW; Emmitte KA
    J Med Chem; 2015 Nov; 58(22):9027-40. PubMed ID: 26524606
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of Potent Tetrazole Free Fatty Acid Receptor 2 Antagonists.
    Valentini A; Schultz-Knudsen K; Højgaard Hansen A; Tsakoumagkou A; Jenkins L; Christensen HB; Manandhar A; Milligan G; Ulven T; Rexen Ulven E
    J Med Chem; 2023 May; 66(9):6105-6121. PubMed ID: 37129317
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.