169 related articles for article (PubMed ID: 32141297)
1. Structure-Activity Relationship Studies of Tetrahydroquinolone Free Fatty Acid Receptor 3 Modulators.
Ulven ER; Quon T; Sergeev E; Barki N; Brvar M; Hudson BD; Dutta P; Hansen AH; Bielefeldt LØ; Tobin AB; McKenzie CJ; Milligan G; Ulven T
J Med Chem; 2020 Apr; 63(7):3577-3595. PubMed ID: 32141297
[TBL] [Abstract][Full Text] [Related]
2. Structure-activity relationship studies of tetrahydroquinolone derivatives as GPR41 modulators.
Inuki S; Miyamoto J; Hashimoto N; Shimizu H; Tabuchi H; Kawai A; Greiner LC; Kimura I; Ohno H
Bioorg Med Chem Lett; 2024 Jul; 107():129758. PubMed ID: 38641152
[TBL] [Abstract][Full Text] [Related]
3. Ligands at the Free Fatty Acid Receptors 2/3 (GPR43/GPR41).
Milligan G; Bolognini D; Sergeev E
Handb Exp Pharmacol; 2017; 236():17-32. PubMed ID: 27757758
[TBL] [Abstract][Full Text] [Related]
4. Complex pharmacology of novel allosteric free fatty acid 3 receptor ligands.
Hudson BD; Christiansen E; Murdoch H; Jenkins L; Hansen AH; Madsen O; Ulven T; Milligan G
Mol Pharmacol; 2014 Aug; 86(2):200-10. PubMed ID: 24870406
[TBL] [Abstract][Full Text] [Related]
5. Agonism and allosterism: the pharmacology of the free fatty acid receptors FFA2 and FFA3.
Milligan G; Stoddart LA; Smith NJ
Br J Pharmacol; 2009 Sep; 158(1):146-53. PubMed ID: 19719777
[TBL] [Abstract][Full Text] [Related]
6. Free fatty acid receptors: structural models and elucidation of ligand binding interactions.
Tikhonova IG; Poerio E
BMC Struct Biol; 2015 Sep; 15():16. PubMed ID: 26346819
[TBL] [Abstract][Full Text] [Related]
7. Short-chain free fatty acid receptors FFA2/GPR43 and FFA3/GPR41 as new potential therapeutic targets.
Ulven T
Front Endocrinol (Lausanne); 2012; 3():111. PubMed ID: 23060857
[TBL] [Abstract][Full Text] [Related]
8. Chemogenetics defines a short-chain fatty acid receptor gut-brain axis.
Barki N; Bolognini D; Börjesson U; Jenkins L; Riddell J; Hughes DI; Ulven T; Hudson BD; Ulven ER; Dekker N; Tobin AB; Milligan G
Elife; 2022 Mar; 11():. PubMed ID: 35229717
[TBL] [Abstract][Full Text] [Related]
9. New positive allosteric modulators of the metabotropic glutamate receptor 2 (mGluR2): identification and synthesis of N-propyl-8-chloro-6-substituted isoquinolones.
Trabanco AA; Duvey G; Cid JM; Macdonald GJ; Cluzeau P; Nhem V; Furnari R; Behaj N; Poulain G; Finn T; Lavreysen H; Poli S; Raux A; Thollon Y; Poirier N; D'Addona D; Andrés JI; Lutjens R; Le Poul E; Imogai H; Rocher JP
Bioorg Med Chem Lett; 2011 Feb; 21(3):971-6. PubMed ID: 21232953
[TBL] [Abstract][Full Text] [Related]
10. Free fatty acid receptor 3 is a key target of short chain fatty acid. What is the impact on the sympathetic nervous system?
López Soto EJ; Gambino LO; Mustafá ER
Channels (Austin); 2014; 8(3):169-71. PubMed ID: 24762451
[TBL] [Abstract][Full Text] [Related]
11. Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3.
Schmidt J; Smith NJ; Christiansen E; Tikhonova IG; Grundmann M; Hudson BD; Ward RJ; Drewke C; Milligan G; Kostenis E; Ulven T
J Biol Chem; 2011 Mar; 286(12):10628-40. PubMed ID: 21220428
[TBL] [Abstract][Full Text] [Related]
12. Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia.
Nøhr MK; Egerod KL; Christiansen SH; Gille A; Offermanns S; Schwartz TW; Møller M
Neuroscience; 2015 Apr; 290():126-37. PubMed ID: 25637492
[TBL] [Abstract][Full Text] [Related]
13. Identification and functional characterization of allosteric agonists for the G protein-coupled receptor FFA2.
Lee T; Schwandner R; Swaminath G; Weiszmann J; Cardozo M; Greenberg J; Jaeckel P; Ge H; Wang Y; Jiao X; Liu J; Kayser F; Tian H; Li Y
Mol Pharmacol; 2008 Dec; 74(6):1599-609. PubMed ID: 18818303
[TBL] [Abstract][Full Text] [Related]
14. Free fatty acid receptor 3 differentially contributes to β-cell compensation under high-fat diet and streptozotocin stress.
Priyadarshini M; Cole C; Oroskar G; Ludvik AE; Wicksteed B; He C; Layden BT
Am J Physiol Regul Integr Comp Physiol; 2020 Apr; 318(4):R691-R700. PubMed ID: 32073900
[TBL] [Abstract][Full Text] [Related]
15. Application of GPCR Structures for Modelling of Free Fatty Acid Receptors.
Tikhonova IG
Handb Exp Pharmacol; 2017; 236():57-77. PubMed ID: 27757764
[TBL] [Abstract][Full Text] [Related]
16. Short-chain fatty acid mitigates adenine-induced chronic kidney disease via FFA2 and FFA3 pathways.
Mikami D; Kobayashi M; Uwada J; Yazawa T; Kamiyama K; Nishimori K; Nishikawa Y; Nishikawa S; Yokoi S; Kimura H; Kimura I; Taniguchi T; Iwano M
Biochim Biophys Acta Mol Cell Biol Lipids; 2020 Jun; 1865(6):158666. PubMed ID: 32061840
[TBL] [Abstract][Full Text] [Related]
17. The first synthetic agonists of FFA2: Discovery and SAR of phenylacetamides as allosteric modulators.
Wang Y; Jiao X; Kayser F; Liu J; Wang Z; Wanska M; Greenberg J; Weiszmann J; Ge H; Tian H; Wong S; Schwandner R; Lee T; Li Y
Bioorg Med Chem Lett; 2010 Jan; 20(2):493-8. PubMed ID: 20005104
[TBL] [Abstract][Full Text] [Related]
18. Synthesis, structure-activity relationships and biological evaluation of 7-phenyl-pyrroloquinolinone 3-amide derivatives as potent antimitotic agents.
Carta D; Bortolozzi R; Sturlese M; Salmaso V; Hamel E; Basso G; Calderan L; Quintieri L; Moro S; Viola G; Ferlin MG
Eur J Med Chem; 2017 Feb; 127():643-660. PubMed ID: 27823884
[TBL] [Abstract][Full Text] [Related]
19. Design of 4-Oxo-1-aryl-1,4-dihydroquinoline-3-carboxamides as Selective Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 2.
Felts AS; Rodriguez AL; Smith KA; Engers JL; Morrison RD; Byers FW; Blobaum AL; Locuson CW; Chang S; Venable DF; Niswender CM; Daniels JS; Conn PJ; Lindsley CW; Emmitte KA
J Med Chem; 2015 Nov; 58(22):9027-40. PubMed ID: 26524606
[TBL] [Abstract][Full Text] [Related]
20. Discovery of Potent Tetrazole Free Fatty Acid Receptor 2 Antagonists.
Valentini A; Schultz-Knudsen K; Højgaard Hansen A; Tsakoumagkou A; Jenkins L; Christensen HB; Manandhar A; Milligan G; Ulven T; Rexen Ulven E
J Med Chem; 2023 May; 66(9):6105-6121. PubMed ID: 37129317
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]