BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

277 related articles for article (PubMed ID: 32142409)

  • 1. A highly responsive pyruvate sensor reveals pathway-regulatory role of the mitochondrial pyruvate carrier MPC.
    Arce-Molina R; Cortés-Molina F; Sandoval PY; Galaz A; Alegría K; Schirmeier S; Barros LF; San Martín A
    Elife; 2020 Mar; 9():. PubMed ID: 32142409
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism.
    Schell JC; Wisidagama DR; Bensard C; Zhao H; Wei P; Tanner J; Flores A; Mohlman J; Sorensen LK; Earl CS; Olson KA; Miao R; Waller TC; Delker D; Kanth P; Jiang L; DeBerardinis RJ; Bronner MP; Li DY; Cox JE; Christofk HR; Lowry WE; Thummel CS; Rutter J
    Nat Cell Biol; 2017 Sep; 19(9):1027-1036. PubMed ID: 28812582
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The mitochondrial pyruvate carrier (MPC) complex mediates one of three pyruvate-supplying pathways that sustain Arabidopsis respiratory metabolism.
    Le XH; Lee CP; Millar AH
    Plant Cell; 2021 Aug; 33(8):2776-2793. PubMed ID: 34137858
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans.
    Bricker DK; Taylor EB; Schell JC; Orsak T; Boutron A; Chen YC; Cox JE; Cardon CM; Van Vranken JG; Dephoure N; Redin C; Boudina S; Gygi SP; Brivet M; Thummel CS; Rutter J
    Science; 2012 Jul; 337(6090):96-100. PubMed ID: 22628558
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency.
    De La Rossa A; Laporte MH; Astori S; Marissal T; Montessuit S; Sheshadri P; Ramos-Fernández E; Mendez P; Khani A; Quairiaux C; Taylor EB; Rutter J; Nunes JM; Carleton A; Duchen MR; Sandi C; Martinou JC
    Elife; 2022 Feb; 11():. PubMed ID: 35188099
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Multifaceted Pyruvate Metabolism: Role of the Mitochondrial Pyruvate Carrier.
    Zangari J; Petrelli F; Maillot B; Martinou JC
    Biomolecules; 2020 Jul; 10(7):. PubMed ID: 32708919
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The mitochondrial pyruvate carrier in health and disease: To carry or not to carry?
    Bender T; Martinou JC
    Biochim Biophys Acta; 2016 Oct; 1863(10):2436-42. PubMed ID: 26826034
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure.
    Cluntun AA; Badolia R; Lettlova S; Parnell KM; Shankar TS; Diakos NA; Olson KA; Taleb I; Tatum SM; Berg JA; Cunningham CN; Van Ry T; Bott AJ; Krokidi AT; Fogarty S; Skedros S; Swiatek WI; Yu X; Luo B; Merx S; Navankasattusas S; Cox JE; Ducker GS; Holland WL; McKellar SH; Rutter J; Drakos SG
    Cell Metab; 2021 Mar; 33(3):629-648.e10. PubMed ID: 33333007
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice.
    Hodges WT; Jarasvaraparn C; Ferguson D; Griffett K; Gill LE; Chen Y; Ilagan MXG; Hegazy L; Elgendy B; Cho K; Patti GJ; McCommis KS; Finck BN
    J Biol Chem; 2022 Feb; 298(2):101554. PubMed ID: 34973337
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification and functional expression of the mitochondrial pyruvate carrier.
    Herzig S; Raemy E; Montessuit S; Veuthey JL; Zamboni N; Westermann B; Kunji ER; Martinou JC
    Science; 2012 Jul; 337(6090):93-6. PubMed ID: 22628554
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel KDM5A/MPC-1 signaling pathway promotes pancreatic cancer progression via redirecting mitochondrial pyruvate metabolism.
    Cui J; Quan M; Xie D; Gao Y; Guha S; Fallon MB; Chen J; Xie K
    Oncogene; 2020 Jan; 39(5):1140-1151. PubMed ID: 31641207
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The mitochondrial pyruvate carrier at the crossroads of intermediary metabolism.
    Yiew NKH; Finck BN
    Am J Physiol Endocrinol Metab; 2022 Jul; 323(1):E33-E52. PubMed ID: 35635330
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A Method for Multiplexed Measurement of Mitochondrial Pyruvate Carrier Activity.
    Gray LR; Rauckhorst AJ; Taylor EB
    J Biol Chem; 2016 Apr; 291(14):7409-17. PubMed ID: 26823462
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Glucagon up-regulates hepatic mitochondrial pyruvate carrier 1 through cAMP-responsive element-binding protein; inhibition of hepatic gluconeogenesis by ginsenoside Rb1.
    Lou MD; Li J; Cheng Y; Xiao N; Ma G; Li P; Liu B; Liu Q; Qi LW
    Br J Pharmacol; 2019 Aug; 176(16):2962-2976. PubMed ID: 31166615
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Monitoring Mitochondrial Pyruvate Carrier Activity in Real Time Using a BRET-Based Biosensor: Investigation of the Warburg Effect.
    Compan V; Pierredon S; Vanderperre B; Krznar P; Marchiq I; Zamboni N; Pouyssegur J; Martinou JC
    Mol Cell; 2015 Aug; 59(3):491-501. PubMed ID: 26253029
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mitochondrial Pyruvate Carrier Function in Health and Disease across the Lifespan.
    Buchanan JL; Taylor EB
    Biomolecules; 2020 Aug; 10(8):. PubMed ID: 32784379
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The yeast mitochondrial pyruvate carrier is a hetero-dimer in its functional state.
    Tavoulari S; Thangaratnarajah C; Mavridou V; Harbour ME; Martinou JC; Kunji ER
    EMBO J; 2019 May; 38(10):. PubMed ID: 30979775
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The mitochondrial pyruvate carrier mediates high fat diet-induced increases in hepatic TCA cycle capacity.
    Rauckhorst AJ; Gray LR; Sheldon RD; Fu X; Pewa AD; Feddersen CR; Dupuy AJ; Gibson-Corley KN; Cox JE; Burgess SC; Taylor EB
    Mol Metab; 2017 Nov; 6(11):1468-1479. PubMed ID: 29107293
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Embryonic Lethality of Mitochondrial Pyruvate Carrier 1 Deficient Mouse Can Be Rescued by a Ketogenic Diet.
    Vanderperre B; Herzig S; Krznar P; Hörl M; Ammar Z; Montessuit S; Pierredon S; Zamboni N; Martinou JC
    PLoS Genet; 2016 May; 12(5):e1006056. PubMed ID: 27176894
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Heart failure-emerging roles for the mitochondrial pyruvate carrier.
    Fernandez-Caggiano M; Eaton P
    Cell Death Differ; 2021 Apr; 28(4):1149-1158. PubMed ID: 33473180
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.