131 related articles for article (PubMed ID: 32144825)
1. High-content imaging and structure-based predictions reveal functional differences between Niemann-Pick C1 variants.
Vanharanta L; Peränen J; Pfisterer SG; Enkavi G; Vattulainen I; Ikonen E
Traffic; 2020 May; 21(5):386-397. PubMed ID: 32144825
[TBL] [Abstract][Full Text] [Related]
2. Molecular dynamics study with mutation shows that N-terminal domain structural re-orientation in Niemann-Pick type C1 is required for proper alignment of cholesterol transport.
Yoon HJ; Jeong H; Lee HH; Jang S
J Neurochem; 2021 Mar; 156(6):967-978. PubMed ID: 32880929
[TBL] [Abstract][Full Text] [Related]
3. ABCA1-dependent mobilization of lysosomal cholesterol requires functional Niemann-Pick C2 but not Niemann-Pick C1 protein.
Boadu E; Nelson RC; Francis GA
Biochim Biophys Acta; 2012 Mar; 1821(3):396-404. PubMed ID: 22179027
[TBL] [Abstract][Full Text] [Related]
4. Niemann-Pick C variant detection by altered sphingolipid trafficking and correlation with mutations within a specific domain of NPC1.
Sun X; Marks DL; Park WD; Wheatley CL; Puri V; O'Brien JF; Kraft DL; Lundquist PA; Patterson MC; Pagano RE; Snow K
Am J Hum Genet; 2001 Jun; 68(6):1361-72. PubMed ID: 11349231
[TBL] [Abstract][Full Text] [Related]
5. Cholesterol Transport in Wild-Type NPC1 and P691S: Molecular Dynamics Simulations Reveal Changes in Dynamical Behavior.
Elghobashi-Meinhardt N
Int J Mol Sci; 2020 Apr; 21(8):. PubMed ID: 32331453
[TBL] [Abstract][Full Text] [Related]
6. The Niemann-Pick C1 protein resides in a vesicular compartment linked to retrograde transport of multiple lysosomal cargo.
Neufeld EB; Wastney M; Patel S; Suresh S; Cooney AM; Dwyer NK; Roff CF; Ohno K; Morris JA; Carstea ED; Incardona JP; Strauss JF; Vanier MT; Patterson MC; Brady RO; Pentchev PG; Blanchette-Mackie EJ
J Biol Chem; 1999 Apr; 274(14):9627-35. PubMed ID: 10092649
[TBL] [Abstract][Full Text] [Related]
7. Mutations in the leucine zipper motif and sterol-sensing domain inactivate the Niemann-Pick C1 glycoprotein.
Watari H; Blanchette-Mackie EJ; Dwyer NK; Watari M; Neufeld EB; Patel S; Pentchev PG; Strauss JF
J Biol Chem; 1999 Jul; 274(31):21861-6. PubMed ID: 10419504
[TBL] [Abstract][Full Text] [Related]
8. Sterol-modulated glycolipid sorting occurs in niemann-pick C1 late endosomes.
Zhang M; Dwyer NK; Neufeld EB; Love DC; Cooney A; Comly M; Patel S; Watari H; Strauss JF; Pentchev PG; Hanover JA; Blanchette-Mackie EJ
J Biol Chem; 2001 Feb; 276(5):3417-25. PubMed ID: 11032830
[TBL] [Abstract][Full Text] [Related]
9. Cholesterol binding to the sterol-sensing region of Niemann Pick C1 protein confines dynamics of its N-terminal domain.
Dubey V; Bozorg B; Wüstner D; Khandelia H
PLoS Comput Biol; 2020 Oct; 16(10):e1007554. PubMed ID: 33021976
[TBL] [Abstract][Full Text] [Related]
10. An overview of the role of Niemann-pick C1 (NPC1) in viral infections and inhibition of viral infections through NPC1 inhibitor.
Ahmad I; Fatemi SN; Ghaheri M; Rezvani A; Khezri DA; Natami M; Yasamineh S; Gholizadeh O; Bahmanyar Z
Cell Commun Signal; 2023 Dec; 21(1):352. PubMed ID: 38098077
[TBL] [Abstract][Full Text] [Related]
11. NPC intracellular cholesterol transporter 1 (NPC1)-mediated cholesterol export from lysosomes.
Pfeffer SR
J Biol Chem; 2019 Feb; 294(5):1706-1709. PubMed ID: 30710017
[TBL] [Abstract][Full Text] [Related]
12. Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins.
Saha P; Shumate JL; Caldwell JG; Elghobashi-Meinhardt N; Lu A; Zhang L; Olsson NE; Elias JE; Pfeffer SR
Elife; 2020 May; 9():. PubMed ID: 32410728
[TBL] [Abstract][Full Text] [Related]
13. Variants in the Niemann-Pick type C gene NPC1 are not associated with Parkinson's disease.
Ouled Amar Bencheikh B; Senkevich K; Rudakou U; Yu E; Mufti K; Ruskey JA; Asayesh F; Laurent SB; Spiegelman D; Fahn S; Waters C; Monchi O; Dauvilliers Y; Espay AJ; Dupré N; Greenbaum L; Hassin-Baer S; Rouleau GA; Alcalay RN; Fon EA; Gan-Or Z
Neurobiol Aging; 2020 Sep; 93():143.e1-143.e4. PubMed ID: 32371106
[TBL] [Abstract][Full Text] [Related]
14. Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by NPC1 and NPC2.
Qian H; Wu X; Du X; Yao X; Zhao X; Lee J; Yang H; Yan N
Cell; 2020 Jul; 182(1):98-111.e18. PubMed ID: 32544384
[TBL] [Abstract][Full Text] [Related]
15. The Niemann-Pick C1 protein in recycling endosomes of presynaptic nerve terminals.
Karten B; Campenot RB; Vance DE; Vance JE
J Lipid Res; 2006 Mar; 47(3):504-14. PubMed ID: 16340014
[TBL] [Abstract][Full Text] [Related]
16. Differential regulation of ATP binding cassette protein A1 expression and ApoA-I lipidation by Niemann-Pick type C1 in murine hepatocytes and macrophages.
Wang MD; Franklin V; Sundaram M; Kiss RS; Ho K; Gallant M; Marcel YL
J Biol Chem; 2007 Aug; 282(31):22525-33. PubMed ID: 17553802
[TBL] [Abstract][Full Text] [Related]
17. Niemann-Pick C1 is a late endosome-resident protein that transiently associates with lysosomes and the trans-Golgi network.
Higgins ME; Davies JP; Chen FW; Ioannou YA
Mol Genet Metab; 1999 Sep; 68(1):1-13. PubMed ID: 10479477
[TBL] [Abstract][Full Text] [Related]
18. Different Trafficking Phenotypes of Niemann-Pick C1 Gene Mutations Correlate with Various Alterations in Lipid Storage, Membrane Composition and Miglustat Amenability.
Brogden G; Shammas H; Walters F; Maalouf K; Das AM; Naim HY; Rizk S
Int J Mol Sci; 2020 Mar; 21(6):. PubMed ID: 32204338
[TBL] [Abstract][Full Text] [Related]
19. Individualized management of genetic diversity in Niemann-Pick C1 through modulation of the Hsp70 chaperone system.
Wang C; Scott SM; Sun S; Zhao P; Hutt DM; Shao H; Gestwicki JE; Balch WE
Hum Mol Genet; 2020 Jan; 29(1):1-19. PubMed ID: 31509197
[TBL] [Abstract][Full Text] [Related]
20. Different Niemann-Pick C1 Genotypes Generate Protein Phenotypes that Vary in their Intracellular Processing, Trafficking and Localization.
Shammas H; Kuech EM; Rizk S; Das AM; Naim HY
Sci Rep; 2019 Mar; 9(1):5292. PubMed ID: 30923329
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]