BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

187 related articles for article (PubMed ID: 32145316)

  • 1. Assessment of the inhibition risk of paris saponins, bioactive compounds from Paris polyphylla, on CYP and UGT enzymes via cocktail inhibition assays.
    Luo H; Xu Y; Sun D; Cheng Y; Sun Z; Gao J; Zhang Y; Wang X
    Regul Toxicol Pharmacol; 2020 Jun; 113():104637. PubMed ID: 32145316
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design and optimization of the cocktail assay for rapid assessment of the activity of UGT enzymes in human and rat liver microsomes.
    Chen A; Zhou X; Cheng Y; Tang S; Liu M; Wang X
    Toxicol Lett; 2018 Oct; 295():379-389. PubMed ID: 30036684
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evaluation of the inhibition risk of shikonin on human and rat UDP-glucuronosyltransferases (UGT) through the cocktail approach.
    Cheng Y; Tang S; Chen A; Zhang Y; Liu M; Wang X
    Toxicol Lett; 2019 Sep; 312():214-221. PubMed ID: 31128210
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Assessment of the inhibition risk of shikonin on cytochrome P450 via cocktail inhibition assay.
    Tang S; Chen A; Zhou X; Zeng L; Liu M; Wang X
    Toxicol Lett; 2017 Nov; 281():74-83. PubMed ID: 28941798
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolic interactions of rosmarinic acid with human cytochrome P450 monooxygenases and uridine diphosphate glucuronosyltransferases.
    Kim SB; Kim KS; Kim DD; Yoon IS
    Biomed Pharmacother; 2019 Feb; 110():111-117. PubMed ID: 30466000
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Direct comparison of UDP-glucuronosyltransferase and cytochrome P450 activities in human liver microsomes, plated and suspended primary human hepatocytes from five liver donors.
    den Braver-Sewradj SP; den Braver MW; Baze A; Decorde J; Fonsi M; Bachellier P; Vermeulen NPE; Commandeur JNM; Richert L; Vos JC
    Eur J Pharm Sci; 2017 Nov; 109():96-110. PubMed ID: 28778465
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In vitro inhibition of human liver cytochrome P450 (CYP) and UDP-glucuronosyltransferase (UGT) enzymes by rose bengal: system-dependent effects on inhibitory potential.
    Kazmi F; Haupt LJ; Horkman JR; Smith BD; Buckley DB; Wachter EA; Singer JM
    Xenobiotica; 2014 Jul; 44(7):606-14. PubMed ID: 24405273
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Evaluation of the in vitro/in vivo drug interaction potential of BST204, a purified dry extract of ginseng, and its four bioactive ginsenosides through cytochrome P450 inhibition/induction and UDP-glucuronosyltransferase inhibition.
    Zheng YF; Bae SH; Choi EJ; Park JB; Kim SO; Jang MJ; Park GH; Shin WG; Oh E; Bae SK
    Food Chem Toxicol; 2014 Jun; 68():117-27. PubMed ID: 24632066
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Protein-protein interactions between rat hepatic cytochromes P450 (P450s) and UDP-glucuronosyltransferases (UGTs): evidence for the functionally active UGT in P450-UGT complex.
    Ishii Y; Iwanaga M; Nishimura Y; Takeda S; Ikushiro S; Nagata K; Yamazoe Y; Mackenzie PI; Yamada H
    Drug Metab Pharmacokinet; 2007 Oct; 22(5):367-76. PubMed ID: 17965520
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of human drug-metabolising cytochrome P450 and UDP-glucuronosyltransferase enzyme activities in vitro by uremic toxins.
    Barnes KJ; Rowland A; Polasek TM; Miners JO
    Eur J Clin Pharmacol; 2014 Sep; 70(9):1097-106. PubMed ID: 24954688
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A cytochrome P450 monooxygenase responsible for the C-22 hydroxylation step in the Paris polyphylla steroidal saponin biosynthesis pathway.
    Yin Y; Gao L; Zhang X; Gao W
    Phytochemistry; 2018 Dec; 156():116-123. PubMed ID: 30268044
    [TBL] [Abstract][Full Text] [Related]  

  • 12. AM-2201 Inhibits Multiple Cytochrome P450 and Uridine 5'-Diphospho-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes.
    Kim JH; Kwon SS; Kong TY; Cheong JC; Kim HS; In MK; Lee HS
    Molecules; 2017 Mar; 22(3):. PubMed ID: 28287454
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of polyphyllin D, a steroidal saponin in Paris polyphylla, in growth inhibition of human breast cancer cells and in xenograft.
    Lee MS; Yuet-Wa JC; Kong SK; Yu B; Eng-Choon VO; Nai-Ching HW; Chung-Wai TM; Fung KP
    Cancer Biol Ther; 2005 Nov; 4(11):1248-54. PubMed ID: 16258257
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evaluation of the inhibition potential of plumbagin against cytochrome P450 using LC-MS/MS and cocktail approach.
    Chen A; Zhou X; Tang S; Liu M; Wang X
    Sci Rep; 2016 Jun; 6():28482. PubMed ID: 27329697
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Optimized assays for human UDP-glucuronosyltransferase (UGT) activities: altered alamethicin concentration and utility to screen for UGT inhibitors.
    Walsky RL; Bauman JN; Bourcier K; Giddens G; Lapham K; Negahban A; Ryder TF; Obach RS; Hyland R; Goosen TC
    Drug Metab Dispos; 2012 May; 40(5):1051-65. PubMed ID: 22357286
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of cytochrome P450 and uridine 5'-diphospho-glucuronosyltransferases by MAM-2201 in human liver microsomes.
    Kong TY; Kim JH; Kwon SS; Cheong JC; Kim HS; In MK; Lee HS
    Arch Pharm Res; 2017 Jun; 40(6):727-735. PubMed ID: 28484907
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibitory Effects of Aschantin on Cytochrome P450 and Uridine 5'-diphospho-glucuronosyltransferase Enzyme Activities in Human Liver Microsomes.
    Kwon SS; Kim JH; Jeong HU; Cho YY; Oh SR; Lee HS
    Molecules; 2016 Apr; 21(5):. PubMed ID: 27128896
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In vitro metabolism of eupatilin by multiple cytochrome P450 and UDP-glucuronosyltransferase enzymes.
    Lee HS; Ji HY; Park EJ; Kim SY
    Xenobiotica; 2007 Aug; 37(8):803-17. PubMed ID: 17701830
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In Vitro Metabolism of Auriculasin and Its Inhibitory Effects on Human Cytochrome P450 and UDP-Glucuronosyltransferase Enzymes.
    Shi X; Zhang G; Ge G; Guo Z; Song Y; Su D; Shan L
    Chem Res Toxicol; 2019 Oct; 32(10):2125-2134. PubMed ID: 31515991
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Product inhibition of UDP-glucuronosyltransferase (UGT) enzymes by UDP obfuscates the inhibitory effects of UGT substrates.
    Fujiwara R; Nakajima M; Yamanaka H; Katoh M; Yokoi T
    Drug Metab Dispos; 2008 Feb; 36(2):361-7. PubMed ID: 17998297
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.