212 related articles for article (PubMed ID: 32147437)
1. HDAC6 inhibition promotes α-tubulin acetylation and ameliorates CMT2A peripheral neuropathy in mice.
Picci C; Wong VSC; Costa CJ; McKinnon MC; Goldberg DC; Swift M; Alam NM; Prusky GT; Shen S; Kozikowski AP; Willis DE; Langley B
Exp Neurol; 2020 Jun; 328():113281. PubMed ID: 32147437
[TBL] [Abstract][Full Text] [Related]
2. Tetrahydroquinoline-Capped Histone Deacetylase 6 Inhibitor SW-101 Ameliorates Pathological Phenotypes in a Charcot-Marie-Tooth Type 2A Mouse Model.
Shen S; Picci C; Ustinova K; Benoy V; Kutil Z; Zhang G; Tavares MT; Pavlíček J; Zimprich CA; Robers MB; Van Den Bosch L; Bařinka C; Langley B; Kozikowski AP
J Med Chem; 2021 Apr; 64(8):4810-4840. PubMed ID: 33830764
[TBL] [Abstract][Full Text] [Related]
3. HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1-induced Charcot-Marie-Tooth disease.
d'Ydewalle C; Krishnan J; Chiheb DM; Van Damme P; Irobi J; Kozikowski AP; Vanden Berghe P; Timmerman V; Robberecht W; Van Den Bosch L
Nat Med; 2011 Jul; 17(8):968-74. PubMed ID: 21785432
[TBL] [Abstract][Full Text] [Related]
4. Bicyclic-Capped Histone Deacetylase 6 Inhibitors with Improved Activity in a Model of Axonal Charcot-Marie-Tooth Disease.
Shen S; Benoy V; Bergman JA; Kalin JH; Frojuello M; Vistoli G; Haeck W; Van Den Bosch L; Kozikowski AP
ACS Chem Neurosci; 2016 Feb; 7(2):240-58. PubMed ID: 26599234
[TBL] [Abstract][Full Text] [Related]
5. HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease.
Benoy V; Van Helleputte L; Prior R; d'Ydewalle C; Haeck W; Geens N; Scheveneels W; Schevenels B; Cader MZ; Talbot K; Kozikowski AP; Vanden Berghe P; Van Damme P; Robberecht W; Van Den Bosch L
Brain; 2018 Mar; 141(3):673-687. PubMed ID: 29415205
[TBL] [Abstract][Full Text] [Related]
6. Novel HDAC6 Inhibitors Increase Tubulin Acetylation and Rescue Axonal Transport of Mitochondria in a Model of Charcot-Marie-Tooth Type 2F.
Adalbert R; Kaieda A; Antoniou C; Loreto A; Yang X; Gilley J; Hoshino T; Uga K; Makhija MT; Coleman MP
ACS Chem Neurosci; 2020 Feb; 11(3):258-267. PubMed ID: 31845794
[TBL] [Abstract][Full Text] [Related]
7. Development of Improved HDAC6 Inhibitors as Pharmacological Therapy for Axonal Charcot-Marie-Tooth Disease.
Benoy V; Vanden Berghe P; Jarpe M; Van Damme P; Robberecht W; Van Den Bosch L
Neurotherapeutics; 2017 Apr; 14(2):417-428. PubMed ID: 27957719
[TBL] [Abstract][Full Text] [Related]
8. Aberrant GlyRS-HDAC6 interaction linked to axonal transport deficits in Charcot-Marie-Tooth neuropathy.
Mo Z; Zhao X; Liu H; Hu Q; Chen XQ; Pham J; Wei N; Liu Z; Zhou J; Burgess RW; Pfaff SL; Caskey CT; Wu C; Bai G; Yang XL
Nat Commun; 2018 Mar; 9(1):1007. PubMed ID: 29520015
[TBL] [Abstract][Full Text] [Related]
9. Brain Penetrable Histone Deacetylase 6 Inhibitor SW-100 Ameliorates Memory and Learning Impairments in a Mouse Model of Fragile X Syndrome.
Kozikowski AP; Shen S; Pardo M; Tavares MT; Szarics D; Benoy V; Zimprich CA; Kutil Z; Zhang G; Bařinka C; Robers MB; Van Den Bosch L; Eubanks JH; Jope RS
ACS Chem Neurosci; 2019 Mar; 10(3):1679-1695. PubMed ID: 30511829
[TBL] [Abstract][Full Text] [Related]
10. Mitochondrial Dysfunction and Pharmacodynamics of Mitofusin Activation in Murine Charcot-Marie-Tooth Disease Type 2A.
Franco A; Dang X; Zhang L; Molinoff PB; Dorn GW
J Pharmacol Exp Ther; 2022 Nov; 383(2):137-148. PubMed ID: 36507849
[TBL] [Abstract][Full Text] [Related]
11. HDAC6 inhibition protects cardiomyocytes against doxorubicin-induced acute damage by improving α-tubulin acetylation.
Song R; Yang Y; Lei H; Wang G; Huang Y; Xue W; Wang Y; Yao L; Zhu Y
J Mol Cell Cardiol; 2018 Nov; 124():58-69. PubMed ID: 30315806
[TBL] [Abstract][Full Text] [Related]
12. Burst mitofusin activation reverses neuromuscular dysfunction in murine CMT2A.
Franco A; Dang X; Walton EK; Ho JN; Zablocka B; Ly C; Miller TM; Baloh RH; Shy ME; Yoo AS; Dorn GW
Elife; 2020 Oct; 9():. PubMed ID: 33074106
[TBL] [Abstract][Full Text] [Related]
13. HDAC6 inhibition by tubastatin A is protective against oxidative stress in a photoreceptor cell line and restores visual function in a zebrafish model of inherited blindness.
Leyk J; Daly C; Janssen-Bienhold U; Kennedy BN; Richter-Landsberg C
Cell Death Dis; 2017 Aug; 8(8):e3028. PubMed ID: 29048427
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of histone deacetylase 6 (HDAC6) protects against vincristine-induced peripheral neuropathies and inhibits tumor growth.
Van Helleputte L; Kater M; Cook DP; Eykens C; Rossaert E; Haeck W; Jaspers T; Geens N; Vanden Berghe P; Gysemans C; Mathieu C; Robberecht W; Van Damme P; Cavaletti G; Jarpe M; Van Den Bosch L
Neurobiol Dis; 2018 Mar; 111():59-69. PubMed ID: 29197621
[TBL] [Abstract][Full Text] [Related]
15. Selective HDAC6 inhibition prevents TNF-α-induced lung endothelial cell barrier disruption and endotoxin-induced pulmonary edema.
Yu J; Ma Z; Shetty S; Ma M; Fu J
Am J Physiol Lung Cell Mol Physiol; 2016 Jul; 311(1):L39-47. PubMed ID: 27190059
[TBL] [Abstract][Full Text] [Related]
16. Rutin increases alpha-tubulin acetylation via histone deacetylase 6 inhibition.
Çetin Ö; Sari S; Erdem-Yurter H; Bora G
Drug Dev Res; 2022 Jun; 83(4):993-1002. PubMed ID: 35266183
[TBL] [Abstract][Full Text] [Related]
17. Early onset Charcot-Marie-Tooth neuropathy type 2A and severe developmental delay: expanding the clinical phenotype of MFN2-related neuropathy.
Tufano M; Cappuccio G; Terrone G; Manganelli F; Pisciotta C; Geroldi A; Capponi S; Del Giudice E
J Peripher Nerv Syst; 2015 Dec; 20(4):415-8. PubMed ID: 26307494
[TBL] [Abstract][Full Text] [Related]
18. Neuronal complexity is attenuated in preclinical models of migraine and restored by HDAC6 inhibition.
Bertels Z; Singh H; Dripps I; Siegersma K; Tipton AF; Witkowski WD; Sheets Z; Shah P; Conway C; Mangutov E; Ao M; Petukhova V; Karumudi B; Petukhov PA; Baca SM; Rasenick MM; Pradhan AA
Elife; 2021 Apr; 10():. PubMed ID: 33856345
[TBL] [Abstract][Full Text] [Related]
19. Genetic epidemiology of Charcot-Marie-Tooth disease.
Braathen GJ
Acta Neurol Scand Suppl; 2012; (193):iv-22. PubMed ID: 23106488
[TBL] [Abstract][Full Text] [Related]
20. MFN2-dependent recruitment of ATAT1 coordinates mitochondria motility with alpha-tubulin acetylation and is disrupted in CMT2A.
Kumar A; Larrea D; Pero ME; Infante P; Conenna M; Shin GJ; Grueber WB; Di Marcotullio L; Area-Gomez E; Bartolini F
bioRxiv; 2023 Mar; ():. PubMed ID: 36993604
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
