217 related articles for article (PubMed ID: 32152544)
1. Deep mutational scanning reveals the structural basis for α-synuclein activity.
Newberry RW; Leong JT; Chow ED; Kampmann M; DeGrado WF
Nat Chem Biol; 2020 Jun; 16(6):653-659. PubMed ID: 32152544
[TBL] [Abstract][Full Text] [Related]
2. Structures of the E46K mutant-type α-synuclein protein and impact of E46K mutation on the structures of the wild-type α-synuclein protein.
Wise-Scira O; Dunn A; Aloglu AK; Sakallioglu IT; Coskuner O
ACS Chem Neurosci; 2013 Mar; 4(3):498-508. PubMed ID: 23374074
[TBL] [Abstract][Full Text] [Related]
3. Robust Sequence Determinants of α-Synuclein Toxicity in Yeast Implicate Membrane Binding.
Newberry RW; Arhar T; Costello J; Hartoularos GC; Maxwell AM; Naing ZZC; Pittman M; Reddy NR; Schwarz DMC; Wassarman DR; Wu TS; Barrero D; Caggiano C; Catching A; Cavazos TB; Estes LS; Faust B; Fink EA; Goldman MA; Gomez YK; Gordon MG; Gunsalus LM; Hoppe N; Jaime-Garza M; Johnson MC; Jones MG; Kung AF; Lopez KE; Lumpe J; Martyn C; McCarthy EE; Miller-Vedam LE; Navarro EJ; Palar A; Pellegrino J; Saylor W; Stephens CA; Strickland J; Torosyan H; Wankowicz SA; Wong DR; Wong G; Redding S; Chow ED; DeGrado WF; Kampmann M
ACS Chem Biol; 2020 Aug; 15(8):2137-2153. PubMed ID: 32786289
[TBL] [Abstract][Full Text] [Related]
4. Structures and free energy landscapes of the wild-type and A30P mutant-type α-synuclein proteins with dynamics.
Wise-Scira O; Aloglu AK; Dunn A; Sakallioglu IT; Coskuner O
ACS Chem Neurosci; 2013 Mar; 4(3):486-97. PubMed ID: 23374072
[TBL] [Abstract][Full Text] [Related]
5. The lipid-binding domain of wild type and mutant alpha-synuclein: compactness and interconversion between the broken and extended helix forms.
Georgieva ER; Ramlall TF; Borbat PP; Freed JH; Eliezer D
J Biol Chem; 2010 Sep; 285(36):28261-74. PubMed ID: 20592036
[TBL] [Abstract][Full Text] [Related]
6. Structures and free energy landscapes of the A53T mutant-type α-synuclein protein and impact of A53T mutation on the structures of the wild-type α-synuclein protein with dynamics.
Coskuner O; Wise-Scira O
ACS Chem Neurosci; 2013 Jul; 4(7):1101-13. PubMed ID: 23607785
[TBL] [Abstract][Full Text] [Related]
7. Pathogenic mutations shift the equilibria of alpha-synuclein single molecules towards structured conformers.
Brucale M; Sandal M; Di Maio S; Rampioni A; Tessari I; Tosatto L; Bisaglia M; Bubacco L; Samorì B
Chembiochem; 2009 Jan; 10(1):176-83. PubMed ID: 19067456
[TBL] [Abstract][Full Text] [Related]
8. Phase transitions and structure analysis in wild-type, A30P, E46K, and A53T mutants of α-synuclein.
Healey MA; Woodside MT; Tuszynski JA
Eur Biophys J; 2016 May; 45(4):355-64. PubMed ID: 26695014
[TBL] [Abstract][Full Text] [Related]
9. Structures of segments of α-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation.
Zhao M; Cascio D; Sawaya MR; Eisenberg D
Protein Sci; 2011 Jun; 20(6):996-1004. PubMed ID: 21462277
[TBL] [Abstract][Full Text] [Related]
10. Sequence determinants regulating fibrillation of human alpha-synuclein.
Koo HJ; Lee HJ; Im H
Biochem Biophys Res Commun; 2008 Apr; 368(3):772-8. PubMed ID: 18261982
[TBL] [Abstract][Full Text] [Related]
11. A four-amino acid linker between repeats in the α-synuclein sequence is important for fibril formation.
Shvadchak VV; Subramaniam V
Biochemistry; 2014 Jan; 53(2):279-81. PubMed ID: 24397337
[TBL] [Abstract][Full Text] [Related]
12. The status of the terminal regions of α-synuclein in different forms of aggregates during fibrillization.
Marvian AT; Aliakbari F; Mohammad-Beigi H; Ahmadi ZA; Mehrpooyan S; Lermyte F; Nasouti M; Collingwood JF; Otzen DE; Morshedi D
Int J Biol Macromol; 2020 Jul; 155():543-550. PubMed ID: 32240735
[TBL] [Abstract][Full Text] [Related]
13. Familial Mutations May Switch Conformational Preferences in α-Synuclein Fibrils.
Xu L; Ma B; Nussinov R; Thompson D
ACS Chem Neurosci; 2017 Apr; 8(4):837-849. PubMed ID: 28075555
[TBL] [Abstract][Full Text] [Related]
14. Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity.
Stephens AD; Zacharopoulou M; Moons R; Fusco G; Seetaloo N; Chiki A; Woodhams PJ; Mela I; Lashuel HA; Phillips JJ; De Simone A; Sobott F; Schierle GSK
Nat Commun; 2020 Jun; 11(1):2820. PubMed ID: 32499486
[TBL] [Abstract][Full Text] [Related]
15. Comparison of Kinetics, Toxicity, Oligomer Formation, and Membrane Binding Capacity of α-Synuclein Familial Mutations at the A53 Site, Including the Newly Discovered A53V Mutation.
Mohite GM; Kumar R; Panigrahi R; Navalkar A; Singh N; Datta D; Mehra S; Ray S; Gadhe LG; Das S; Singh N; Chatterjee D; Kumar A; Maji SK
Biochemistry; 2018 Sep; 57(35):5183-5187. PubMed ID: 29771508
[TBL] [Abstract][Full Text] [Related]
16. The role of the acidic domain of α-synuclein in amyloid fibril formation: a molecular dynamics study.
Park S; Yoon J; Jang S; Lee K; Shin S
J Biomol Struct Dyn; 2016; 34(2):376-83. PubMed ID: 25869255
[TBL] [Abstract][Full Text] [Related]
17. Effect of the A30P mutation on the structural dynamics of micelle-bound αSynuclein released in water: a molecular dynamics study.
Chatterjee P; Sengupta N
Eur Biophys J; 2012 May; 41(5):483-9. PubMed ID: 22446722
[TBL] [Abstract][Full Text] [Related]
18. Membrane-induced initial structure of α-synuclein control its amyloidogenesis on model membranes.
Terakawa MS; Lee YH; Kinoshita M; Lin Y; Sugiki T; Fukui N; Ikenoue T; Kawata Y; Goto Y
Biochim Biophys Acta Biomembr; 2018 Mar; 1860(3):757-766. PubMed ID: 29273335
[TBL] [Abstract][Full Text] [Related]
19. Biasing the native α-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity.
Carija A; Pinheiro F; Pujols J; Brás IC; Lázaro DF; Santambrogio C; Grandori R; Outeiro TF; Navarro S; Ventura S
Redox Biol; 2019 Apr; 22():101135. PubMed ID: 30769283
[TBL] [Abstract][Full Text] [Related]
20. Distinct hydration properties of wild-type and familial point mutant A53T of α-synuclein associated with Parkinson's disease.
Hazy E; Bokor M; Kalmar L; Gelencser A; Kamasa P; Han KH; Tompa K; Tompa P
Biophys J; 2011 Nov; 101(9):2260-6. PubMed ID: 22067166
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]