These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. Analysis of the AAA sensor-2 motif in the C-terminal ATPase domain of Hsp104 with a site-specific fluorescent probe of nucleotide binding. Hattendorf DA; Lindquist SL Proc Natl Acad Sci U S A; 2002 Mar; 99(5):2732-7. PubMed ID: 11867765 [TBL] [Abstract][Full Text] [Related]
5. Structural determinants for protein unfolding and translocation by the Hsp104 protein disaggregase. Lee J; Sung N; Yeo L; Chang C; Lee S; Tsai FTF Biosci Rep; 2017 Dec; 37(6):. PubMed ID: 29175998 [TBL] [Abstract][Full Text] [Related]
6. Spiraling in Control: Structures and Mechanisms of the Hsp104 Disaggregase. Shorter J; Southworth DR Cold Spring Harb Perspect Biol; 2019 Aug; 11(8):. PubMed ID: 30745294 [TBL] [Abstract][Full Text] [Related]
7. Conserved distal loop residues in the Hsp104 and ClpB middle domain contact nucleotide-binding domain 2 and enable Hsp70-dependent protein disaggregation. Desantis ME; Sweeny EA; Snead D; Leung EH; Go MS; Gupta K; Wendler P; Shorter J J Biol Chem; 2014 Jan; 289(2):848-67. PubMed ID: 24280225 [TBL] [Abstract][Full Text] [Related]
9. Selective Hsp70-Dependent Docking of Hsp104 to Protein Aggregates Protects the Cell from the Toxicity of the Disaggregase. Chamera T; Kłosowska A; Janta A; Wyszkowski H; Obuchowski I; Gumowski K; Liberek K J Mol Biol; 2019 May; 431(11):2180-2196. PubMed ID: 31026451 [TBL] [Abstract][Full Text] [Related]
10. Cooperative kinetics of both Hsp104 ATPase domains and interdomain communication revealed by AAA sensor-1 mutants. Hattendorf DA; Lindquist SL EMBO J; 2002 Jan; 21(1-2):12-21. PubMed ID: 11782421 [TBL] [Abstract][Full Text] [Related]
11. Evidence for an unfolding/threading mechanism for protein disaggregation by Saccharomyces cerevisiae Hsp104. Lum R; Tkach JM; Vierling E; Glover JR J Biol Chem; 2004 Jul; 279(28):29139-46. PubMed ID: 15128736 [TBL] [Abstract][Full Text] [Related]
12. Structural and mechanistic insights into Hsp104 function revealed by synchrotron X-ray footprinting. Sweeny EA; Tariq A; Gurpinar E; Go MS; Sochor MA; Kan ZY; Mayne L; Englander SW; Shorter J J Biol Chem; 2020 Feb; 295(6):1517-1538. PubMed ID: 31882541 [TBL] [Abstract][Full Text] [Related]
13. Mechanistic and Structural Insights into the Prion-Disaggregase Activity of Hsp104. Sweeny EA; Shorter J J Mol Biol; 2016 May; 428(9 Pt B):1870-85. PubMed ID: 26608812 [TBL] [Abstract][Full Text] [Related]
14. Hsp104 and Potentiated Variants Can Operate as Distinct Nonprocessive Translocases. Durie CL; Lin J; Scull NW; Mack KL; Jackrel ME; Sweeny EA; Castellano LM; Shorter J; Lucius AL Biophys J; 2019 May; 116(10):1856-1872. PubMed ID: 31027887 [TBL] [Abstract][Full Text] [Related]
15. Potentiating Hsp104 activity via phosphomimetic mutations in the middle domain. Tariq A; Lin J; Noll MM; Torrente MP; Mack KL; Murillo OH; Jackrel ME; Shorter J FEMS Yeast Res; 2018 Aug; 18(5):. PubMed ID: 29788207 [TBL] [Abstract][Full Text] [Related]
16. The mammalian disaggregase machinery: Hsp110 synergizes with Hsp70 and Hsp40 to catalyze protein disaggregation and reactivation in a cell-free system. Shorter J PLoS One; 2011; 6(10):e26319. PubMed ID: 22022600 [TBL] [Abstract][Full Text] [Related]