These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

188 related articles for article (PubMed ID: 32159944)

  • 1. The Influence of Pathogenic Mutations in α-Synuclein on Biophysical and Structural Characteristics of Amyloid Fibrils.
    Ruggeri FS; Flagmeier P; Kumita JR; Meisl G; Chirgadze DY; Bongiovanni MN; Knowles TPJ; Dobson CM
    ACS Nano; 2020 May; 14(5):5213-5222. PubMed ID: 32159944
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutations associated with familial Parkinson's disease alter the initiation and amplification steps of α-synuclein aggregation.
    Flagmeier P; Meisl G; Vendruscolo M; Knowles TP; Dobson CM; Buell AK; Galvagnion C
    Proc Natl Acad Sci U S A; 2016 Sep; 113(37):10328-33. PubMed ID: 27573854
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid.
    Conway KA; Harper JD; Lansbury PT
    Biochemistry; 2000 Mar; 39(10):2552-63. PubMed ID: 10704204
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparative Analysis of the Relative Fragmentation Stabilities of Polymorphic Alpha-Synuclein Amyloid Fibrils.
    Sanami S; Purton TJ; Smith DP; Tuite MF; Xue WF
    Biomolecules; 2022 Apr; 12(5):. PubMed ID: 35625557
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A triple-emission fluorescent probe reveals distinctive amyloid fibrillar polymorphism of wild-type alpha-synuclein and its familial Parkinson's disease mutants.
    Celej MS; Caarls W; Demchenko AP; Jovin TM
    Biochemistry; 2009 Aug; 48(31):7465-72. PubMed ID: 19586054
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structures of fibrils formed by α-synuclein hereditary disease mutant H50Q reveal new polymorphs.
    Boyer DR; Li B; Sun C; Fan W; Sawaya MR; Jiang L; Eisenberg DS
    Nat Struct Mol Biol; 2019 Nov; 26(11):1044-1052. PubMed ID: 31695184
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Quantitative morphological analysis reveals ultrastructural diversity of amyloid fibrils from alpha-synuclein mutants.
    van Raaij ME; Segers-Nolten IM; Subramaniam V
    Biophys J; 2006 Dec; 91(11):L96-8. PubMed ID: 16997873
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural features of α-synuclein amyloid fibrils revealed by Raman spectroscopy.
    Flynn JD; McGlinchey RP; Walker RL; Lee JC
    J Biol Chem; 2018 Jan; 293(3):767-776. PubMed ID: 29191831
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Analysis of sheep α-synuclein provides a molecular strategy for the reduction of fibrillation.
    Bickle L; Hopwood JJ; Karageorgos L
    Biochim Biophys Acta Proteins Proteom; 2017 Mar; 1865(3):261-273. PubMed ID: 28007442
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Physicochemical characterization of the G51D mutation of α-synuclein that is responsible for its severe cytotoxicity.
    Murata T; Tochio N; Utsunomiya-Tate N
    Neurosci Lett; 2021 Aug; 760():136077. PubMed ID: 34161822
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dissociation of amyloid fibrils of alpha-synuclein and transthyretin by pressure reveals their reversible nature and the formation of water-excluded cavities.
    Foguel D; Suarez MC; Ferrão-Gonzales AD; Porto TC; Palmieri L; Einsiedler CM; Andrade LR; Lashuel HA; Lansbury PT; Kelly JW; Silva JL
    Proc Natl Acad Sci U S A; 2003 Aug; 100(17):9831-6. PubMed ID: 12900507
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pressure effects on α-synuclein amyloid fibrils: An experimental investigation on their dissociation and reversible nature.
    Piccirilli F; Plotegher N; Spinozzi F; Bubacco L; Mariani P; Beltramini M; Tessari I; Militello V; Perucchi A; Amenitsch H; Baldassarri E; Steinhart M; Lupi S; Ortore MG
    Arch Biochem Biophys; 2017 Aug; 627():46-55. PubMed ID: 28624352
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Familial Mutations May Switch Conformational Preferences in α-Synuclein Fibrils.
    Xu L; Ma B; Nussinov R; Thompson D
    ACS Chem Neurosci; 2017 Apr; 8(4):837-849. PubMed ID: 28075555
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The H50Q mutation induces a 10-fold decrease in the solubility of α-synuclein.
    Porcari R; Proukakis C; Waudby CA; Bolognesi B; Mangione PP; Paton JF; Mullin S; Cabrita LD; Penco A; Relini A; Verona G; Vendruscolo M; Stoppini M; Tartaglia GG; Camilloni C; Christodoulou J; Schapira AH; Bellotti V
    J Biol Chem; 2015 Jan; 290(4):2395-404. PubMed ID: 25505181
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Parkinson's disease associated mutation E46K of α-synuclein triggers the formation of a distinct fibril structure.
    Zhao K; Li Y; Liu Z; Long H; Zhao C; Luo F; Sun Y; Tao Y; Su XD; Li D; Li X; Liu C
    Nat Commun; 2020 May; 11(1):2643. PubMed ID: 32457390
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Distinct Mechanisms Determine α-Synuclein Fibril Morphology during Growth and Maturation.
    Sidhu A; Segers-Nolten I; Raussens V; Claessens MM; Subramaniam V
    ACS Chem Neurosci; 2017 Mar; 8(3):538-547. PubMed ID: 28292187
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Covalent α-synuclein dimers: chemico-physical and aggregation properties.
    Pivato M; De Franceschi G; Tosatto L; Frare E; Kumar D; Aioanei D; Brucale M; Tessari I; Bisaglia M; Samori B; de Laureto PP; Bubacco L
    PLoS One; 2012; 7(12):e50027. PubMed ID: 23272053
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effect of Disease-Associated P123H and V70M Mutations on β-Synuclein Fibrillation.
    Sharma K; Mehra S; Sawner AS; Markam PS; Panigrahi R; Navalkar A; Chatterjee D; Kumar R; Kadu P; Patel K; Ray S; Kumar A; Maji SK
    ACS Chem Neurosci; 2020 Sep; 11(18):2836-2848. PubMed ID: 32833434
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Biophysics of Parkinson's disease: structure and aggregation of alpha-synuclein.
    Uversky VN; Eliezer D
    Curr Protein Pept Sci; 2009 Oct; 10(5):483-99. PubMed ID: 19538146
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Conserved core of amyloid fibrils of wild type and A30P mutant α-synuclein.
    Cho MK; Kim HY; Fernandez CO; Becker S; Zweckstetter M
    Protein Sci; 2011 Feb; 20(2):387-95. PubMed ID: 21280130
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.