BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

188 related articles for article (PubMed ID: 32161443)

  • 1. AZD4547 Attenuates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting Inflammation: The Role of FGFR1 in Renal Tubular Epithelial Cells.
    Chen X; Zhang X; Xu J; Zhao Y; Bao J; Zheng Z; Han J
    Drug Des Devel Ther; 2020; 14():833-844. PubMed ID: 32161443
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Nephroprotective Effect of TNF Receptor-Associated Factor 6 (TRAF6) Blockade on LPS-Induced Acute Renal Injury Through the Inhibition if Inflammation and Oxidative Stress.
    Chen X; Zhao Y; Xu J; Bao J; Zhao J; Chen J; Chen G; Han J
    Med Sci Monit; 2020 Jan; 26():e919698. PubMed ID: 31929494
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Translating the therapeutic potential of AZD4547 in FGFR1-amplified non-small cell lung cancer through the use of patient-derived tumor xenograft models.
    Zhang J; Zhang L; Su X; Li M; Xie L; Malchers F; Fan S; Yin X; Xu Y; Liu K; Dong Z; Zhu G; Qian Z; Tang L; Schöttle J; Zhan P; Ji Q; Kilgour E; Smith PD; Brooks AN; Thomas RK; Gavine PR
    Clin Cancer Res; 2012 Dec; 18(24):6658-67. PubMed ID: 23082000
    [TBL] [Abstract][Full Text] [Related]  

  • 4. UCP2 alleviates tubular epithelial cell apoptosis in lipopolysaccharide-induced acute kidney injury by decreasing ROS production.
    Zhong X; He J; Zhang X; Li C; Tian X; Xia W; Gan H; Xia Y
    Biomed Pharmacother; 2019 Jul; 115():108914. PubMed ID: 31071510
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ang II (Angiotensin II)-Induced FGFR1 (Fibroblast Growth Factor Receptor 1) Activation in Tubular Epithelial Cells Promotes Hypertensive Kidney Fibrosis and Injury.
    Xu Z; Luo W; Chen L; Zhuang Z; Yang D; Qian J; Khan ZA; Guan X; Wang Y; Li X; Liang G
    Hypertension; 2022 Sep; 79(9):2028-2041. PubMed ID: 35862110
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Usp9x contributes to the development of sepsis-induced acute kidney injury by promoting inflammation and apoptosis in renal tubular epithelial cells via activation of the TLR4/nf-κb pathway.
    Gong S; Xiong H; Lei Y; Huang S; Ouyang Y; Cao C; Wang Y
    Ren Fail; 2024 Dec; 46(2):2361089. PubMed ID: 38874156
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protective Effects of Simvastatin on Endotoxin-Induced Acute Kidney Injury through Activation of Tubular Epithelial Cells' Survival and Hindering Cytochrome C-Mediated Apoptosis.
    Nežić L; Škrbić R; Amidžić L; Gajanin R; Milovanović Z; Nepovimova E; Kuča K; Jaćević V
    Int J Mol Sci; 2020 Sep; 21(19):. PubMed ID: 33008033
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The FGFR1 V561M Gatekeeper Mutation Drives AZD4547 Resistance through STAT3 Activation and EMT.
    Ryan MR; Sohl CD; Luo B; Anderson KS
    Mol Cancer Res; 2019 Feb; 17(2):532-543. PubMed ID: 30257990
    [TBL] [Abstract][Full Text] [Related]  

  • 9. FGFR inhibitor, AZD4547, impedes the stemness of mammary epithelial cells in the premalignant tissues of MMTV-ErbB2 transgenic mice.
    Zhao Q; Parris AB; Howard EW; Zhao M; Ma Z; Guo Z; Xing Y; Yang X
    Sci Rep; 2017 Sep; 7(1):11306. PubMed ID: 28900173
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Insight into resistance mechanisms of AZD4547 and E3810 to FGFR1 gatekeeper mutation via theoretical study.
    Liang D; Chen Q; Guo Y; Zhang T; Guo W
    Drug Des Devel Ther; 2017; 11():451-461. PubMed ID: 28255231
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RIPK3 mediates renal tubular epithelial cell apoptosis in endotoxin‑induced acute kidney injury.
    Zhang S; Li R; Dong W; Yang H; Zhang L; Chen Y; Wang W; Li C; Wu Y; Ye Z; Zhao X; Li Z; Zhang M; Liu S; Liang X
    Mol Med Rep; 2019 Aug; 20(2):1613-1620. PubMed ID: 31257491
    [TBL] [Abstract][Full Text] [Related]  

  • 12. FGFR1 Is a Potential Prognostic Biomarker and Therapeutic Target in Head and Neck Squamous Cell Carcinoma.
    Koole K; Brunen D; van Kempen PM; Noorlag R; de Bree R; Lieftink C; van Es RJ; Bernards R; Willems SM
    Clin Cancer Res; 2016 Aug; 22(15):3884-93. PubMed ID: 26936917
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antioxidative, Antiapoptotic, and Anti-Inflammatory Effects of Apamin in a Murine Model of Lipopolysaccharide-Induced Acute Kidney Injury.
    Kim JY; Leem J; Park KK
    Molecules; 2020 Dec; 25(23):. PubMed ID: 33287398
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MicroRNA‑93 inhibits the apoptosis and inflammatory response of tubular epithelial cells via the PTEN/AKT/mTOR pathway in acute kidney injury.
    Zhan Y; Zhu M; Liu S; Lu J; Ni Z; Cai H; Zhang W
    Mol Med Rep; 2021 Sep; 24(3):. PubMed ID: 34296286
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Abnormal lncRNA CCAT1/microRNA-155/SIRT1 axis promoted inflammatory response and apoptosis of tubular epithelial cells in LPS caused acute kidney injury.
    Lu S; Dong L; Jing X; Gen-Yang C; Zhan-Zheng Z
    Mitochondrion; 2020 Jul; 53():76-90. PubMed ID: 32243922
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Upregulation of miR-21 by Ghrelin Ameliorates Ischemia/Reperfusion-Induced Acute Kidney Injury by Inhibiting Inflammation and Cell Apoptosis.
    Zhang W; Shu L
    DNA Cell Biol; 2016 Aug; 35(8):417-25. PubMed ID: 27152763
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rutaecarpine derivative Cpd-6c alleviates acute kidney injury by targeting PDE4B, a key enzyme mediating inflammation in cisplatin nephropathy.
    Liu XQ; Jin J; Li Z; Jiang L; Dong YH; Cai YT; Wu MF; Wang JN; Ma TT; Wen JG; Liu MM; Li J; Wu YG; Meng XM
    Biochem Pharmacol; 2020 Oct; 180():114132. PubMed ID: 32622666
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ulinastatin Attenuates LPS-Induced Inflammation and Inhibits Endoplasmic Reticulum Stress-Induced Apoptosis in Renal Tubular Epithelial Cells via Regulation of the TLR4/NF-κB and Nrf2/HO-1 Pathways.
    Chen F; Zhu J; Wang W
    Inflammation; 2021 Dec; 44(6):2323-2332. PubMed ID: 34585338
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Resistance to FGFR1-targeted therapy leads to autophagy via TAK1/AMPK activation in gastric cancer.
    Peng R; Chen Y; Wei L; Li G; Feng D; Liu S; Jiang R; Zheng S; Chen Y
    Gastric Cancer; 2020 Nov; 23(6):988-1002. PubMed ID: 32617693
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dipeptidyl peptidase-4 inhibitor teneligliptin accelerates recovery from cisplatin-induced acute kidney injury by attenuating inflammation and promoting tubular regeneration.
    Iwakura T; Zhao Z; Marschner JA; Devarapu SK; Yasuda H; Anders HJ
    Nephrol Dial Transplant; 2019 Oct; 34(10):1669-1680. PubMed ID: 30624740
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.