287 related articles for article (PubMed ID: 32164323)
1. Salient Features of Monomeric Alpha-Synuclein Revealed by NMR Spectroscopy.
Kim DH; Lee J; Mok KH; Lee JH; Han KH
Biomolecules; 2020 Mar; 10(3):. PubMed ID: 32164323
[TBL] [Abstract][Full Text] [Related]
2. Insights into the Molecular Mechanisms of Alzheimer's and Parkinson's Diseases with Molecular Simulations: Understanding the Roles of Artificial and Pathological Missense Mutations in Intrinsically Disordered Proteins Related to Pathology.
Coskuner-Weber O; Uversky VN
Int J Mol Sci; 2018 Jan; 19(2):. PubMed ID: 29364151
[TBL] [Abstract][Full Text] [Related]
3. Structural disorder of monomeric α-synuclein persists in mammalian cells.
Theillet FX; Binolfi A; Bekei B; Martorana A; Rose HM; Stuiver M; Verzini S; Lorenz D; van Rossum M; Goldfarb D; Selenko P
Nature; 2016 Feb; 530(7588):45-50. PubMed ID: 26808899
[TBL] [Abstract][Full Text] [Related]
4. Structure and dynamics of the extended-helix state of alpha-synuclein: Intrinsic lability of the linker region.
Sung YH; Eliezer D
Protein Sci; 2018 Jul; 27(7):1314-1324. PubMed ID: 29663556
[TBL] [Abstract][Full Text] [Related]
5. N-terminal acetylation of α-synuclein induces increased transient helical propensity and decreased aggregation rates in the intrinsically disordered monomer.
Kang L; Moriarty GM; Woods LA; Ashcroft AE; Radford SE; Baum J
Protein Sci; 2012 Jul; 21(7):911-7. PubMed ID: 22573613
[TBL] [Abstract][Full Text] [Related]
6. Biasing the native α-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity.
Carija A; Pinheiro F; Pujols J; Brás IC; Lázaro DF; Santambrogio C; Grandori R; Outeiro TF; Navarro S; Ventura S
Redox Biol; 2019 Apr; 22():101135. PubMed ID: 30769283
[TBL] [Abstract][Full Text] [Related]
7. Methionine oxidation in α-synuclein inhibits its propensity for ordered secondary structure.
Ponzini E; De Palma A; Cerboni L; Natalello A; Rossi R; Moons R; Konijnenberg A; Narkiewicz J; Legname G; Sobott F; Mauri P; Santambrogio C; Grandori R
J Biol Chem; 2019 Apr; 294(14):5657-5665. PubMed ID: 30755483
[TBL] [Abstract][Full Text] [Related]
8. Impact of the α-Synuclein Initial Ensemble Structure on Fibrillation Pathways and Kinetics.
Bai J; Cheng K; Liu M; Li C
J Phys Chem B; 2016 Mar; 120(12):3140-7. PubMed ID: 26950519
[TBL] [Abstract][Full Text] [Related]
9. A relationship between the transient structure in the monomeric state and the aggregation propensities of α-synuclein and β-synuclein.
Allison JR; Rivers RC; Christodoulou JC; Vendruscolo M; Dobson CM
Biochemistry; 2014 Nov; 53(46):7170-83. PubMed ID: 25389903
[TBL] [Abstract][Full Text] [Related]
10. A Fragment-Based Method of Creating Small-Molecule Libraries to Target the Aggregation of Intrinsically Disordered Proteins.
Joshi P; Chia S; Habchi J; Knowles TP; Dobson CM; Vendruscolo M
ACS Comb Sci; 2016 Mar; 18(3):144-53. PubMed ID: 26923286
[TBL] [Abstract][Full Text] [Related]
11.
Murrali MG; Schiavina M; Sainati V; Bermel W; Pierattelli R; Felli IC
J Biomol NMR; 2018 Mar; 70(3):167-175. PubMed ID: 29492731
[TBL] [Abstract][Full Text] [Related]
12. Structures of the intrinsically disordered Aβ, tau and α-synuclein proteins in aqueous solution from computer simulations.
Nguyen PH; Derreumaux P
Biophys Chem; 2020 Sep; 264():106421. PubMed ID: 32623047
[TBL] [Abstract][Full Text] [Related]
13. Role of Sporadic Parkinson Disease Associated Mutations A18T and A29S in Enhanced α-Synuclein Fibrillation and Cytotoxicity.
Kumar S; Jangir DK; Kumar R; Kumari M; Bhavesh NS; Maiti TK
ACS Chem Neurosci; 2018 Feb; 9(2):230-240. PubMed ID: 28841377
[TBL] [Abstract][Full Text] [Related]
14. Monitoring the Interaction of α-Synuclein with Calcium Ions through Exclusively Heteronuclear Nuclear Magnetic Resonance Experiments.
Pontoriero L; Schiavina M; Murrali MG; Pierattelli R; Felli IC
Angew Chem Int Ed Engl; 2020 Oct; 59(42):18537-18545. PubMed ID: 32735376
[TBL] [Abstract][Full Text] [Related]
15. Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity.
Stephens AD; Zacharopoulou M; Moons R; Fusco G; Seetaloo N; Chiki A; Woodhams PJ; Mela I; Lashuel HA; Phillips JJ; De Simone A; Sobott F; Schierle GSK
Nat Commun; 2020 Jun; 11(1):2820. PubMed ID: 32499486
[TBL] [Abstract][Full Text] [Related]
16. Probing the Basis of α-Synuclein Aggregation by Comparing Simulations to Single-Molecule Experiments.
Churchill CDM; Healey MA; Preto J; Tuszynski JA; Woodside MT
Biophys J; 2019 Sep; 117(6):1125-1135. PubMed ID: 31477241
[TBL] [Abstract][Full Text] [Related]
17. Epitope region identification challenges of intrinsically disordered proteins in neurodegenerative diseases: Secondary structure dependence of α-synuclein on simulation techniques and force field parameters.
Mandaci SY; Caliskan M; Sariaslan MF; Uversky VN; Coskuner-Weber O
Chem Biol Drug Des; 2020 Jul; 96(1):659-667. PubMed ID: 31903719
[TBL] [Abstract][Full Text] [Related]
18. Structural characterization of alpha-synuclein in an aggregation prone state.
Cho MK; Nodet G; Kim HY; Jensen MR; Bernado P; Fernandez CO; Becker S; Blackledge M; Zweckstetter M
Protein Sci; 2009 Sep; 18(9):1840-6. PubMed ID: 19554627
[TBL] [Abstract][Full Text] [Related]
19. α-Synuclein Misfolding Versus Aggregation Relevance to Parkinson's Disease: Critical Assessment and Modeling.
Berrocal R; Vasquez V; Rao Krs S; Gadad BS; Rao KS
Mol Neurobiol; 2015; 51(3):1417-31. PubMed ID: 25139280
[TBL] [Abstract][Full Text] [Related]
20. Solid-state NMR reveals structural differences between fibrils of wild-type and disease-related A53T mutant alpha-synuclein.
Heise H; Celej MS; Becker S; Riedel D; Pelah A; Kumar A; Jovin TM; Baldus M
J Mol Biol; 2008 Jul; 380(3):444-50. PubMed ID: 18539297
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]