BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 32166747)

  • 1. Function and mutual interaction of BiP-, PERK-, and IRE1α-dependent signalling pathways in vascular tumours.
    Anspach L; Tsaryk R; Seidmann L; Unger RE; Jayasinghe C; Simiantonaki N; Kirkpatrick CJ; Pröls F
    J Pathol; 2020 Jun; 251(2):123-134. PubMed ID: 32166747
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase.
    Merlot AM; Shafie NH; Yu Y; Richardson V; Jansson PJ; Sahni S; Lane DJR; Kovacevic Z; Kalinowski DS; Richardson DR
    Biochem Pharmacol; 2016 Jun; 109():27-47. PubMed ID: 27059255
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel mechanism of enhancing IRE1α-XBP1 signalling via the PERK-ATF4 pathway.
    Tsuru A; Imai Y; Saito M; Kohno K
    Sci Rep; 2016 Apr; 6():24217. PubMed ID: 27052593
    [TBL] [Abstract][Full Text] [Related]  

  • 4. IRE1α dissociates with BiP and inhibits ER stress-mediated apoptosis in cartilage development.
    Han X; Zhou J; Zhang P; Song F; Jiang R; Li M; Xia F; Guo FJ
    Cell Signal; 2013 Nov; 25(11):2136-46. PubMed ID: 23816533
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effects of muscular dystrophy, exercise and blocking activin receptor IIB ligands on the unfolded protein response and oxidative stress.
    Hulmi JJ; Hentilä J; DeRuisseau KC; Oliveira BM; Papaioannou KG; Autio R; Kujala UM; Ritvos O; Kainulainen H; Korkmaz A; Atalay M
    Free Radic Biol Med; 2016 Oct; 99():308-322. PubMed ID: 27554968
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TNFα selectively activates the IRE1α/XBP1 endoplasmic reticulum stress pathway in human airway smooth muscle cells.
    Yap J; Chen X; Delmotte P; Sieck GC
    Am J Physiol Lung Cell Mol Physiol; 2020 Mar; 318(3):L483-L493. PubMed ID: 31940218
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Necroptosis activates UPR sensors without disrupting their binding with GRP78.
    Liang W; Qi W; Geng Y; Wang L; Zhao J; Zhu K; Wu G; Zhang Z; Pan H; Qian L; Yuan J
    Proc Natl Acad Sci U S A; 2021 Sep; 118(39):. PubMed ID: 34544877
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular signal networks and regulating mechanisms of the unfolded protein response.
    Gong J; Wang XZ; Wang T; Chen JJ; Xie XY; Hu H; Yu F; Liu HL; Jiang XY; Fan HD
    J Zhejiang Univ Sci B; 2017 Jan.; 18(1):1-14. PubMed ID: 28070992
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The metastasis suppressor, NDRG1, differentially modulates the endoplasmic reticulum stress response.
    Merlot AM; Porter GM; Sahni S; Lim EG; Peres P; Richardson DR
    Biochim Biophys Acta Mol Basis Dis; 2019 Sep; 1865(9):2094-2110. PubMed ID: 30981813
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Heat Shock Protein 47 Maintains Cancer Cell Growth by Inhibiting the Unfolded Protein Response Transducer IRE1α.
    Yoneda A; Sakai-Sawada K; Minomi K; Tamura Y
    Mol Cancer Res; 2020 Jun; 18(6):847-858. PubMed ID: 32102897
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A Molecular Mechanism for Turning Off IRE1α Signaling during Endoplasmic Reticulum Stress.
    Li X; Sun S; Appathurai S; Sundaram A; Plumb R; Mariappan M
    Cell Rep; 2020 Dec; 33(13):108563. PubMed ID: 33378667
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Fortilin binds IRE1α and prevents ER stress from signaling apoptotic cell death.
    Pinkaew D; Chattopadhyay A; King MD; Chunhacha P; Liu Z; Stevenson HL; Chen Y; Sinthujaroen P; McDougal OM; Fujise K
    Nat Commun; 2017 May; 8(1):18. PubMed ID: 28550308
    [TBL] [Abstract][Full Text] [Related]  

  • 13. EGFR confers radioresistance in human oropharyngeal carcinoma by activating endoplasmic reticulum stress signaling PERK-eIF2α-GRP94 and IRE1α-XBP1-GRP78.
    Zhang M; Han N; Jiang Y; Wang J; Li G; Lv X; Li G; Qiao Q
    Cancer Med; 2018 Dec; 7(12):6234-6246. PubMed ID: 30414263
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dynamic changes in complexes of IRE1α, PERK, and ATF6α during endoplasmic reticulum stress.
    Sundaram A; Appathurai S; Plumb R; Mariappan M
    Mol Biol Cell; 2018 Jun; 29(11):1376-1388. PubMed ID: 29851562
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Imaging of single cell responses to ER stress indicates that the relative dynamics of IRE1/XBP1 and PERK/ATF4 signalling rather than a switch between signalling branches determine cell survival.
    Walter F; Schmid J; Düssmann H; Concannon CG; Prehn JH
    Cell Death Differ; 2015 Sep; 22(9):1502-16. PubMed ID: 25633195
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Noncanonical binding of BiP ATPase domain to Ire1 and Perk is dissociated by unfolded protein CH1 to initiate ER stress signaling.
    Carrara M; Prischi F; Nowak PR; Kopp MC; Ali MM
    Elife; 2015 Feb; 4():. PubMed ID: 25692299
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Altered ratios of pro- and anti-angiogenic VEGF-A variants and pericyte expression of DLL4 disrupt vascular maturation in infantile haemangioma.
    Ye X; Abou-Rayyah Y; Bischoff J; Ritchie A; Sebire NJ; Watts P; Churchill AJ; Bates DO
    J Pathol; 2016 Jun; 239(2):139-51. PubMed ID: 26957058
    [TBL] [Abstract][Full Text] [Related]  

  • 18. UPR proteins IRE1 and PERK switch BiP from chaperone to ER stress sensor.
    Kopp MC; Larburu N; Durairaj V; Adams CJ; Ali MMU
    Nat Struct Mol Biol; 2019 Nov; 26(11):1053-1062. PubMed ID: 31695187
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Punicalagin exerts protective effect against high glucose-induced cellular stress and neural tube defects.
    Zhong J; Reece EA; Yang P
    Biochem Biophys Res Commun; 2015 Nov; 467(2):179-84. PubMed ID: 26453010
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transcriptional regulation of VEGF-A by the unfolded protein response pathway.
    Ghosh R; Lipson KL; Sargent KE; Mercurio AM; Hunt JS; Ron D; Urano F
    PLoS One; 2010 Mar; 5(3):e9575. PubMed ID: 20221394
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.