BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

332 related articles for article (PubMed ID: 32170726)

  • 21. Bax/Bak-dependent, Drp1-independent Targeting of X-linked Inhibitor of Apoptosis Protein (XIAP) into Inner Mitochondrial Compartments Counteracts Smac/DIABLO-dependent Effector Caspase Activation.
    Hamacher-Brady A; Brady NR
    J Biol Chem; 2015 Sep; 290(36):22005-18. PubMed ID: 26134559
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Smac mimetic-induced upregulation of interferon-β sensitizes glioblastoma to temozolomide-induced cell death.
    Marschall V; Fulda S
    Cell Death Dis; 2015 Sep; 6(9):e1888. PubMed ID: 26379193
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Impairment of antioxidant defense via glutathione depletion sensitizes acute lymphoblastic leukemia cells for Smac mimetic-induced cell death.
    Schoeneberger H; Belz K; Schenk B; Fulda S
    Oncogene; 2015 Jul; 34(31):4032-43. PubMed ID: 25381820
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The pan-HDAC inhibitor vorinostat potentiates the activity of the proteasome inhibitor carfilzomib in human DLBCL cells in vitro and in vivo.
    Dasmahapatra G; Lembersky D; Kramer L; Fisher RI; Friedberg J; Dent P; Grant S
    Blood; 2010 Jun; 115(22):4478-87. PubMed ID: 20233973
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The SMAC mimetic BV6 induces cell death and sensitizes different cell lines to TNF-α and TRAIL-induced apoptosis.
    El-Mesery M; Shaker ME; Elgaml A
    Exp Biol Med (Maywood); 2016 Dec; 241(18):2015-2022. PubMed ID: 27465142
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Critical role of mitochondria-mediated apoptosis for JNJ-26481585-induced antitumor activity in rhabdomyosarcoma.
    Heinicke U; Kupka J; Fichter I; Fulda S
    Oncogene; 2016 Jul; 35(28):3729-41. PubMed ID: 26616861
    [TBL] [Abstract][Full Text] [Related]  

  • 27. NF-κB contributes to Smac mimetic-conferred protection from tunicamycin-induced apoptosis.
    Abhari BA; McCarthy N; Agostinis P; Fulda S
    Apoptosis; 2019 Apr; 24(3-4):269-277. PubMed ID: 30680482
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Targeting inhibitor of apoptosis proteins by Smac mimetic elicits cell death in poor prognostic subgroups of chronic lymphocytic leukemia.
    Opel D; Schnaiter A; Dodier D; Jovanovic M; Gerhardinger A; Idler I; Mertens D; Bullinger L; Stilgenbauer S; Fulda S
    Int J Cancer; 2015 Dec; 137(12):2959-70. PubMed ID: 26096065
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Smac induces cytochrome c release and apoptosis independently from Bax/Bcl-x(L) in a strictly caspase-3-dependent manner in human carcinoma cells.
    Hasenjäger A; Gillissen B; Müller A; Normand G; Hemmati PG; Schuler M; Dörken B; Daniel PT
    Oncogene; 2004 Jun; 23(26):4523-35. PubMed ID: 15064710
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The proteasome inhibitor MG132 potentiates TRAIL receptor agonist-induced apoptosis by stabilizing tBid and Bik in human head and neck squamous cell carcinoma cells.
    Sung ES; Park KJ; Choi HJ; Kim CH; Kim YS
    Exp Cell Res; 2012 Aug; 318(13):1564-76. PubMed ID: 22513214
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The BH3-mimetic GX15-070 synergizes with bortezomib in mantle cell lymphoma by enhancing Noxa-mediated activation of Bak.
    Pérez-Galán P; Roué G; Villamor N; Campo E; Colomer D
    Blood; 2007 May; 109(10):4441-9. PubMed ID: 17227835
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Identification of non-canonical NF-κB signaling as a critical mediator of Smac mimetic-stimulated migration and invasion of glioblastoma cells.
    Tchoghandjian A; Jennewein C; Eckhardt I; Rajalingam K; Fulda S
    Cell Death Dis; 2013 Mar; 4(3):e564. PubMed ID: 23538445
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Smac mimetic induces cell death in a large proportion of primary acute myeloid leukemia samples, which correlates with defined molecular markers.
    Lueck SC; Russ AC; Botzenhardt U; Schlenk RF; Zobel K; Deshayes K; Vucic D; Döhner H; Döhner K; Fulda S; Bullinger L
    Oncotarget; 2016 Aug; 7(31):49539-49551. PubMed ID: 27385100
    [TBL] [Abstract][Full Text] [Related]  

  • 34. JNJ-26481585 primes rhabdomyosarcoma cells for chemotherapeutics by engaging the mitochondrial pathway of apoptosis.
    Heinicke U; Kupka J; Fulda S
    Oncotarget; 2015 Nov; 6(35):37836-51. PubMed ID: 26473375
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Bortezomib-induced sensitization of malignant human glioma cells to vorinostat-induced apoptosis depends on reactive oxygen species production, mitochondrial dysfunction, Noxa upregulation, Mcl-1 cleavage, and DNA damage.
    Premkumar DR; Jane EP; Agostino NR; DiDomenico JD; Pollack IF
    Mol Carcinog; 2013 Feb; 52(2):118-33. PubMed ID: 22086447
    [TBL] [Abstract][Full Text] [Related]  

  • 36. PSAP induces a unique Apaf-1 and Smac-dependent mitochondrial apoptotic pathway independent of Bcl-2 family proteins.
    Li T; Zeng L; Gao W; Cui MZ; Fu X; Xu X
    Biochim Biophys Acta; 2013 Mar; 1832(3):453-74. PubMed ID: 23207240
    [TBL] [Abstract][Full Text] [Related]  

  • 37. BH3-mimetics and BET-inhibitors elicit enhanced lethality in malignant glioma.
    Ishida CT; Bianchetti E; Shu C; Halatsch ME; Westhoff MA; Karpel-Massler G; Siegelin MD
    Oncotarget; 2017 May; 8(18):29558-29573. PubMed ID: 28418907
    [TBL] [Abstract][Full Text] [Related]  

  • 38. NF-κB is required for Smac mimetic-mediated sensitization of glioblastoma cells for γ-irradiation-induced apoptosis.
    Berger R; Jennewein C; Marschall V; Karl S; Cristofanon S; Wagner L; Vellanki SH; Hehlgans S; Rödel F; Debatin KM; Ludolph AC; Fulda S
    Mol Cancer Ther; 2011 Oct; 10(10):1867-75. PubMed ID: 21859841
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Therapeutic targeting of necroptosis by Smac mimetic bypasses apoptosis resistance in acute myeloid leukemia cells.
    Safferthal C; Rohde K; Fulda S
    Oncogene; 2017 Mar; 36(11):1487-1502. PubMed ID: 27869161
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The SMAC mimetic BV6 sensitizes colorectal cancer cells to ionizing radiation by interfering with DNA repair processes and enhancing apoptosis.
    Hehlgans S; Oppermann J; Reichert S; Fulda S; Rödel C; Rödel F
    Radiat Oncol; 2015 Sep; 10():198. PubMed ID: 26383618
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 17.