155 related articles for article (PubMed ID: 32173197)
1. Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors.
Hou Z; Min W; Zhang R; Niu A; Li Y; Cao L; Han J; Luo C; Yang P; Ding H
Bioorg Med Chem Lett; 2020 May; 30(9):127061. PubMed ID: 32173197
[TBL] [Abstract][Full Text] [Related]
2. Identification and Characterizations of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Scaffold Hopping- and 2D-Molecular Fingerprint-Based Similarity Search.
Ding H; Lu WC; Hu JC; Liu YC; Zhang CH; Lian FL; Zhang NX; Meng FW; Luo C; Chen KX
Molecules; 2018 Mar; 23(3):. PubMed ID: 29498708
[TBL] [Abstract][Full Text] [Related]
3. Computational discovery and biological evaluation of novel inhibitors targeting histone-lysine N-methyltransferase SET7.
Min W; Hou Z; Zhang F; Xie S; Yuan K; Dong H; Wang L; Qi L; Luo C; Ding H; Yang P
Bioorg Med Chem; 2020 Apr; 28(7):115372. PubMed ID: 32088124
[TBL] [Abstract][Full Text] [Related]
4. Discovery and Optimization of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Pharmacophore- and Docking-Based Virtual Screening.
Meng F; Cheng S; Ding H; Liu S; Liu Y; Zhu K; Chen S; Lu J; Xie Y; Li L; Liu R; Shi Z; Zhou Y; Liu YC; Zheng M; Jiang H; Lu W; Liu H; Luo C
J Med Chem; 2015 Oct; 58(20):8166-81. PubMed ID: 26390175
[TBL] [Abstract][Full Text] [Related]
5. Development of homogeneous nonradioactive methyltransferase and demethylase assays targeting histone H3 lysine 4.
Gauthier N; Caron M; Pedro L; Arcand M; Blouin J; Labonté A; Normand C; Paquet V; Rodenbrock A; Roy M; Rouleau N; Beaudet L; Padrós J; Rodriguez-Suarez R
J Biomol Screen; 2012 Jan; 17(1):49-58. PubMed ID: 21940714
[TBL] [Abstract][Full Text] [Related]
6. Identification of Cyproheptadine as an Inhibitor of SET Domain Containing Lysine Methyltransferase 7/9 (Set7/9) That Regulates Estrogen-Dependent Transcription.
Takemoto Y; Ito A; Niwa H; Okamura M; Fujiwara T; Hirano T; Handa N; Umehara T; Sonoda T; Ogawa K; Tariq M; Nishino N; Dan S; Kagechika H; Yamori T; Yokoyama S; Yoshida M
J Med Chem; 2016 Apr; 59(8):3650-60. PubMed ID: 27088648
[TBL] [Abstract][Full Text] [Related]
7. Non-histone Methylation of SET7/9 and its Biological Functions.
Gao L; Yu W; Song P; Li Q
Recent Pat Anticancer Drug Discov; 2022; 17(3):231-243. PubMed ID: 34856916
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and biological evaluation of benzimidazole derivatives as the G9a Histone Methyltransferase inhibitors that induce autophagy and apoptosis of breast cancer cells.
Zhang J; Yao D; Jiang Y; Huang J; Yang S; Wang J
Bioorg Chem; 2017 Jun; 72():168-181. PubMed ID: 28460359
[TBL] [Abstract][Full Text] [Related]
9. Discovery of novel small molecule inhibitors of lysine methyltransferase G9a and their mechanism in leukemia cell lines.
Kondengaden SM; Luo LF; Huang K; Zhu M; Zang L; Bataba E; Wang R; Luo C; Wang B; Li KK; Wang PG
Eur J Med Chem; 2016 Oct; 122():382-393. PubMed ID: 27393948
[TBL] [Abstract][Full Text] [Related]
10. Identification of Rpl29 as a major substrate of the lysine methyltransferase Set7/9.
Hamidi T; Singh AK; Veland N; Vemulapalli V; Chen J; Hardikar S; Bao J; Fry CJ; Yang V; Lee KA; Guo A; Arrowsmith CH; Bedford MT; Chen T
J Biol Chem; 2018 Aug; 293(33):12770-12780. PubMed ID: 29959229
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and biological activity of selenopsammaplin A and its analogues as antitumor agents with DOT1L inhibitory activity.
Ju Han H; Sub Byun W; Ho Lee G; Kyung Kim W; Jang K; Yang S; Yang J; Woo Ha M; Hong S; Lee J; Shin J; Bong Oh K; Kook Lee S; Park HG
Bioorg Med Chem; 2021 Apr; 35():116072. PubMed ID: 33636429
[TBL] [Abstract][Full Text] [Related]
12. Identification of DOT1L inhibitors by structure-based virtual screening adapted from a nucleoside-focused library.
Gibbons GS; Chakraborty A; Grigsby SM; Umeano AC; Liao C; Moukha-Chafiq O; Pathak V; Mathew B; Lee YT; Dou Y; Schürer SC; Reynolds RC; Snowden TS; Nikolovska-Coleska Z
Eur J Med Chem; 2020 Mar; 189():112023. PubMed ID: 31978781
[TBL] [Abstract][Full Text] [Related]
13. Discovery of an in vivo chemical probe of the lysine methyltransferases G9a and GLP.
Liu F; Barsyte-Lovejoy D; Li F; Xiong Y; Korboukh V; Huang XP; Allali-Hassani A; Janzen WP; Roth BL; Frye SV; Arrowsmith CH; Brown PJ; Vedadi M; Jin J
J Med Chem; 2013 Nov; 56(21):8931-42. PubMed ID: 24102134
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of SET Domain-Containing Lysine Methyltransferase 7/9 Ameliorates Renal Fibrosis.
Sasaki K; Doi S; Nakashima A; Irifuku T; Yamada K; Kokoroishi K; Ueno T; Doi T; Hida E; Arihiro K; Kohno N; Masaki T
J Am Soc Nephrol; 2016 Jan; 27(1):203-15. PubMed ID: 26045091
[TBL] [Abstract][Full Text] [Related]
15. Steric structure-activity relationship of cyproheptadine derivatives as inhibitors of histone methyltransferase Set7/9.
Fujiwara T; Ohira K; Urushibara K; Ito A; Yoshida M; Kanai M; Tanatani A; Kagechika H; Hirano T
Bioorg Med Chem; 2016 Sep; 24(18):4318-4323. PubMed ID: 27448773
[TBL] [Abstract][Full Text] [Related]
16. Development of Novel Inhibitors for Histone Methyltransferase SET7/9 based on Cyproheptadine.
Hirano T; Fujiwara T; Niwa H; Hirano M; Ohira K; Okazaki Y; Sato S; Umehara T; Maemoto Y; Ito A; Yoshida M; Kagechika H
ChemMedChem; 2018 Aug; 13(15):1530-1540. PubMed ID: 29882380
[TBL] [Abstract][Full Text] [Related]
17. Using 'biased-privileged' scaffolds to identify lysine methyltransferase inhibitors.
Kashyap S; Sandler J; Peters U; Martinez EJ; Kapoor TM
Bioorg Med Chem; 2014 Apr; 22(7):2253-60. PubMed ID: 24650704
[TBL] [Abstract][Full Text] [Related]
18. 5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma.
Wang S; Yang H; Su M; Lian F; Cong Z; Wei R; Zhou Y; Li X; Zheng X; Li C; Fu X; Han X; Shi Q; Li C; Zhang N; Geng M; Liu H; Li J; Huang X; Wang J
Eur J Med Chem; 2021 Oct; 222():113592. PubMed ID: 34147909
[TBL] [Abstract][Full Text] [Related]
19. Computer-Aided Discovery of Massonianoside B as a Novel Selective DOT1L Inhibitor.
Chen J; Park HJ
ACS Chem Biol; 2019 May; 14(5):873-881. PubMed ID: 30951287
[TBL] [Abstract][Full Text] [Related]
20. Insights for the design of protein lysine methyltransferase G9a inhibitors.
Charles MRC; Dhayalan A; Hsieh HP; Coumar MS
Future Med Chem; 2019 May; 11(9):993-1014. PubMed ID: 31141392
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
