BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 32181355)

  • 1. MTH1 inhibitor amplifies the lethality of reactive oxygen species to tumor in photodynamic therapy.
    Zhao L; Li J; Su Y; Yang L; Chen L; Qiang L; Wang Y; Xiang H; Tham HP; Peng J; Zhao Y
    Sci Adv; 2020 Mar; 6(10):eaaz0575. PubMed ID: 32181355
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Delivery of MutT homolog 1 inhibitor by functionalized graphene oxide nanoparticles for enhanced chemo-photodynamic therapy triggers cell death in osteosarcoma.
    Huang X; Chen J; Wu W; Yang W; Zhong B; Qing X; Shao Z
    Acta Biomater; 2020 Jun; 109():229-243. PubMed ID: 32294550
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Augment of Oxidative Damage with Enhanced Photodynamic Process and MTH1 Inhibition for Tumor Therapy.
    Hu JJ; Chen Y; Li ZH; Peng SY; Sun Y; Zhang XZ
    Nano Lett; 2019 Aug; 19(8):5568-5576. PubMed ID: 31262183
    [TBL] [Abstract][Full Text] [Related]  

  • 4. AXL and CAV-1 play a role for MTH1 inhibitor TH1579 sensitivity in cutaneous malignant melanoma.
    Das I; Gad H; Bräutigam L; Pudelko L; Tuominen R; Höiom V; Almlöf I; Rajagopal V; Hansson J; Helleday T; Egyházi Brage S; Warpman Berglund U
    Cell Death Differ; 2020 Jul; 27(7):2081-2098. PubMed ID: 31919461
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Delivery of MTH1 inhibitor (TH287) and MDR1 siRNA via hyaluronic acid-based mesoporous silica nanoparticles for oral cancers treatment.
    Shi XL; Li Y; Zhao LM; Su LW; Ding G
    Colloids Surf B Biointerfaces; 2019 Jan; 173():599-606. PubMed ID: 30352381
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MTH1 inhibition synergizes with ROS-inducing agents to trigger cervical cancer cells undergoing parthanatos.
    Li C; Xue Y; Wu J; Zhang L; Yang T; Ai M; Han J; Zheng X; Wang R; Boldogh I; Ba X
    Biochim Biophys Acta Mol Basis Dis; 2024 Jun; 1870(5):167190. PubMed ID: 38657912
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Validation and development of MTH1 inhibitors for treatment of cancer.
    Warpman Berglund U; Sanjiv K; Gad H; Kalderén C; Koolmeister T; Pham T; Gokturk C; Jafari R; Maddalo G; Seashore-Ludlow B; Chernobrovkin A; Manoilov A; Pateras IS; Rasti A; Jemth AS; Almlöf I; Loseva O; Visnes T; Einarsdottir BO; Gaugaz FZ; Saleh A; Platzack B; Wallner OA; Vallin KS; Henriksson M; Wakchaure P; Borhade S; Herr P; Kallberg Y; Baranczewski P; Homan EJ; Wiita E; Nagpal V; Meijer T; Schipper N; Rudd SG; Bräutigam L; Lindqvist A; Filppula A; Lee TC; Artursson P; Nilsson JA; Gorgoulis VG; Lehtiö J; Zubarev RA; Scobie M; Helleday T
    Ann Oncol; 2016 Dec; 27(12):2275-2283. PubMed ID: 27827301
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synergistic therapy of chemotherapeutic drugs and MTH1 inhibitors using a pH-sensitive polymeric delivery system for oral squamous cell carcinoma.
    Li X; Li L; Huang Y; Liu B; Chi H; Shi L; Zhang W; Li G; Niu Y; Zhu X
    Biomater Sci; 2017 Sep; 5(10):2068-2078. PubMed ID: 28744533
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sono-Controllable and ROS-Sensitive CRISPR-Cas9 Genome Editing for Augmented/Synergistic Ultrasound Tumor Nanotherapy.
    Pu Y; Yin H; Dong C; Xiang H; Wu W; Zhou B; Du D; Chen Y; Xu H
    Adv Mater; 2021 Nov; 33(45):e2104641. PubMed ID: 34536041
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Potent and specific MTH1 inhibitors targeting gastric cancer.
    Zhou W; Ma L; Yang J; Qiao H; Li L; Guo Q; Ma J; Zhao L; Wang J; Jiang G; Wan X; Adam Goscinski M; Ding L; Zheng Y; Li W; Liu H; Suo Z; Zhao W
    Cell Death Dis; 2019 Jun; 10(6):434. PubMed ID: 31164636
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.
    Gad H; Koolmeister T; Jemth AS; Eshtad S; Jacques SA; Ström CE; Svensson LM; Schultz N; Lundbäck T; Einarsdottir BO; Saleh A; Göktürk C; Baranczewski P; Svensson R; Berntsson RP; Gustafsson R; Strömberg K; Sanjiv K; Jacques-Cordonnier MC; Desroses M; Gustavsson AL; Olofsson R; Johansson F; Homan EJ; Loseva O; Bräutigam L; Johansson L; Höglund A; Hagenkort A; Pham T; Altun M; Gaugaz FZ; Vikingsson S; Evers B; Henriksson M; Vallin KS; Wallner OA; Hammarström LG; Wiita E; Almlöf I; Kalderén C; Axelsson H; Djureinovic T; Puigvert JC; Häggblad M; Jeppsson F; Martens U; Lundin C; Lundgren B; Granelli I; Jensen AJ; Artursson P; Nilsson JA; Stenmark P; Scobie M; Berglund UW; Helleday T
    Nature; 2014 Apr; 508(7495):215-21. PubMed ID: 24695224
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibitor development of MTH1 via high-throughput screening with fragment based library and MTH1 substrate binding cavity.
    Peng C; Li YH; Yu CW; Cheng ZH; Liu JR; Hsu JL; Hsin LW; Huang CT; Juan HF; Chern JW; Cheng YS
    Bioorg Chem; 2021 May; 110():104813. PubMed ID: 33774493
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Broaden sources and reduce expenditure: Tumor-specific transformable oxidative stress nanoamplifier enabling economized photodynamic therapy for reinforced oxidation therapy.
    Xu X; Huang B; Zeng Z; Chen J; Huang Z; Guan Z; Chen M; Huang Y; Zhao C
    Theranostics; 2020; 10(23):10513-10530. PubMed ID: 32929363
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeted co-delivery of a photosensitizer and an antisense oligonucleotide based on an activatable hyaluronic acid nanosystem with endogenous oxygen generation for enhanced photodynamic therapy of hypoxic tumors.
    Wu Y; Ding L; Zheng C; Li H; Wu M; Sun Y; Liu X; Zhang X; Zeng Y
    Acta Biomater; 2022 Nov; 153():419-430. PubMed ID: 36115655
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Platinum-based nanocomposites loaded with MTH1 inhibitor amplify oxidative damage for cancer therapy.
    Song Q; Yang W; Deng X; Zhang Y; Li J; Xing X; Chen W; Liu W; Hu H; Zhang Y
    Colloids Surf B Biointerfaces; 2022 Oct; 218():112715. PubMed ID: 35932557
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel Class of Potent and Cellularly Active Inhibitors Devalidates MTH1 as Broad-Spectrum Cancer Target.
    Ellermann M; Eheim A; Rahm F; Viklund J; Guenther J; Andersson M; Ericsson U; Forsblom R; Ginman T; Lindström J; Silvander C; Trésaugues L; Giese A; Bunse S; Neuhaus R; Weiske J; Quanz M; Glasauer A; Nowak-Reppel K; Bader B; Irlbacher H; Meyer H; Queisser N; Bauser M; Haegebarth A; Gorjánácz M
    ACS Chem Biol; 2017 Aug; 12(8):1986-1992. PubMed ID: 28679043
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Self-Delivered and Self-Monitored Chemo-Photodynamic Nanoparticles with Light-Triggered Synergistic Antitumor Therapies by Downregulation of HIF-1α and Depletion of GSH.
    Zhang Z; Wang R; Huang X; Luo R; Xue J; Gao J; Liu W; Liu F; Feng F; Qu W
    ACS Appl Mater Interfaces; 2020 Feb; 12(5):5680-5694. PubMed ID: 31944660
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fluorinated polymeric micelles to overcome hypoxia and enhance photodynamic cancer therapy.
    Wang Q; Li JM; Yu H; Deng K; Zhou W; Wang CX; Zhang Y; Li KH; Zhuo RX; Huang SW
    Biomater Sci; 2018 Oct; 6(11):3096-3107. PubMed ID: 30306153
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia.
    Sanjiv K; Calderón-Montaño JM; Pham TM; Erkers T; Tsuber V; Almlöf I; Höglund A; Heshmati Y; Seashore-Ludlow B; Nagesh Danda A; Gad H; Wiita E; Göktürk C; Rasti A; Friedrich S; Centio A; Estruch M; Våtsveen TK; Struyf N; Visnes T; Scobie M; Koolmeister T; Henriksson M; Wallner O; Sandvall T; Lehmann S; Theilgaard-Mönch K; Garnett MJ; Östling P; Walfridsson J; Helleday T; Warpman Berglund U
    Cancer Res; 2021 Nov; 81(22):5733-5744. PubMed ID: 34593524
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Adaptation to Chronic-Cycling Hypoxia Renders Cancer Cells Resistant to MTH1-Inhibitor Treatment Which Can Be Counteracted by Glutathione Depletion.
    Hansel C; Hlouschek J; Xiang K; Melnikova M; Thomale J; Helleday T; Jendrossek V; Matschke J
    Cells; 2021 Nov; 10(11):. PubMed ID: 34831264
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.