BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 32190865)

  • 21. Rational cyclization-based minimization of entropy penalty upon the binding of Nrf2-derived linear peptides to Keap1: A new strategy to improve therapeutic peptide activity against sepsis.
    Chen K; Huang L; Shen B
    Biophys Chem; 2019 Jan; 244():22-28. PubMed ID: 30465941
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Activation of the Nrf2/ARE pathway via S-alkylation of cysteine 151 in the chemopreventive agent-sensor Keap1 protein by falcarindiol, a conjugated diacetylene compound.
    Ohnuma T; Nakayama S; Anan E; Nishiyama T; Ogura K; Hiratsuka A
    Toxicol Appl Pharmacol; 2010 Apr; 244(1):27-36. PubMed ID: 20026152
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Structurally manipulated antioxidant peptides derived from wheat bran: Preparation and identification.
    Zhuang M; Li J; Wang A; Li G; Ke S; Wang X; Ning M; Sheng Z; Wang B; Zhou Z
    Food Chem; 2024 Jun; 442():138465. PubMed ID: 38266414
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Structural and mechanistic insights into the Keap1-Nrf2 system as a route to drug discovery.
    Madden SK; Itzhaki LS
    Biochim Biophys Acta Proteins Proteom; 2020 Jul; 1868(7):140405. PubMed ID: 32120017
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Bis-Michael Acceptors as Novel Probes to Study the Keap1/Nrf2/ARE Pathway.
    Deny LJ; Traboulsi H; Cantin AM; Marsault É; Richter MV; Bélanger G
    J Med Chem; 2016 Oct; 59(20):9431-9442. PubMed ID: 27682717
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Emerging Substrate Proteins of Kelch-like ECH Associated Protein 1 (Keap1) and Potential Challenges for the Development of Small-Molecule Inhibitors of the Keap1-Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Protein-Protein Interaction.
    Zhang Y; Shi Z; Zhou Y; Xiao Q; Wang H; Peng Y
    J Med Chem; 2020 Aug; 63(15):7986-8002. PubMed ID: 32233486
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Role of human Keap1 S53 and S293 residues in modulating the binding of Keap1 to Nrf2.
    Wei S; Pei Y; Wang Y; Guan H; Huang Y; Xing T; Johnson RW; Wang D
    Biochimie; 2019 Mar; 158():73-81. PubMed ID: 30576774
    [TBL] [Abstract][Full Text] [Related]  

  • 28. S-Glutathionylation of Keap1: a new role for glutathione S-transferase pi in neuronal protection.
    Carvalho AN; Marques C; Guedes RC; Castro-Caldas M; Rodrigues E; van Horssen J; Gama MJ
    FEBS Lett; 2016 May; 590(10):1455-66. PubMed ID: 27086966
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Structural Characteristics and Antioxidant Mechanism of Donkey-Hide Gelatin Peptides by Molecular Dynamics Simulation.
    Liang R; Xu L; Fan C; Cao L; Guo X
    Molecules; 2023 Dec; 28(24):. PubMed ID: 38138465
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The Keap1/Nrf2-ARE Pathway as a Pharmacological Target for Chalcones.
    de Freitas Silva M; Pruccoli L; Morroni F; Sita G; Seghetti F; Viegas C; Tarozzi A
    Molecules; 2018 Jul; 23(7):. PubMed ID: 30037040
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Computational Screening for the Anticancer Potential of Seed-Derived Antioxidant Peptides: A Cheminformatic Approach.
    Chai TT; Koh JA; Wong CC; Sabri MZ; Wong FC
    Molecules; 2021 Dec; 26(23):. PubMed ID: 34885982
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Identification of novel antioxidant peptides from snakehead (Channa argus) soup generated during gastrointestinal digestion and insights into the anti-oxidation mechanisms.
    Zhang J; Li M; Zhang G; Tian Y; Kong F; Xiong S; Zhao S; Jia D; Manyande A; Du H
    Food Chem; 2021 Feb; 337():127921. PubMed ID: 32919266
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Coumarins as Modulators of the Keap1/Nrf2/ARE Signaling Pathway.
    Hassanein EHM; Sayed AM; Hussein OE; Mahmoud AM
    Oxid Med Cell Longev; 2020; 2020():1675957. PubMed ID: 32377290
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Structure-Activity and Structure-Conformation Relationships of Aryl Propionic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1/Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1/NRF2) Protein-Protein Interaction.
    Heightman TD; Callahan JF; Chiarparin E; Coyle JE; Griffiths-Jones C; Lakdawala AS; McMenamin R; Mortenson PN; Norton D; Peakman TM; Rich SJ; Richardson C; Rumsey WL; Sanchez Y; Saxty G; Willems HMG; Wolfe L; Woolford AJ; Wu Z; Yan H; Kerns JK; Davies TG
    J Med Chem; 2019 May; 62(9):4683-4702. PubMed ID: 30973731
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Identification of an adaptor protein that facilitates Nrf2-Keap1 complex formation and modulates antioxidant response.
    Zhang Y; Hou Y; Liu C; Li Y; Guo W; Wu JL; Xu D; You X; Pan Y; Chen Y
    Free Radic Biol Med; 2016 Aug; 97():38-49. PubMed ID: 27212020
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Molecular docking and molecular dynamics simulation of wheat gluten-derived antioxidant peptides acting through the Keap1-Nrf2 pathway.
    Liu W; Liu R; Qin Q; Wang H; Zhang X; Meng G
    J Sci Food Agric; 2024 Jun; ():. PubMed ID: 38837798
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Exploring new strategies for grafting binding peptides onto protein loops using a consensus-designed tetratricopeptide repeat scaffold.
    Madden SK; Perez-Riba A; Itzhaki LS
    Protein Sci; 2019 Apr; 28(4):738-745. PubMed ID: 30746804
    [TBL] [Abstract][Full Text] [Related]  

  • 38. GSK3β-mediated Keap1-independent regulation of Nrf2 antioxidant response: A molecular rheostat of acute kidney injury to chronic kidney disease transition.
    Lu M; Wang P; Qiao Y; Jiang C; Ge Y; Flickinger B; Malhotra DK; Dworkin LD; Liu Z; Gong R
    Redox Biol; 2019 Sep; 26():101275. PubMed ID: 31349118
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Gallic acid, a natural polyphenol, protects against tert-butyl hydroperoxide- induced hepatotoxicity by activating ERK-Nrf2-Keap1-mediated antioxidative response.
    Feng RB; Wang Y; He C; Yang Y; Wan JB
    Food Chem Toxicol; 2018 Sep; 119():479-488. PubMed ID: 29066411
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Upregulating Nrf2-dependent antioxidant defenses in Pacific oysters Crassostrea gigas: Investigating the Nrf2/Keap1 pathway in bivalves.
    Danielli NM; Trevisan R; Mello DF; Fischer K; Deconto VS; da Silva Acosta D; Bianchini A; Bainy AC; Dafre AL
    Comp Biochem Physiol C Toxicol Pharmacol; 2017 May; 195():16-26. PubMed ID: 28216009
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.