214 related articles for article (PubMed ID: 32193207)
1. Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications.
Goydel RS; Weber J; Peng H; Qi J; Soden J; Freeth J; Park H; Rader C
J Biol Chem; 2020 May; 295(18):5995-6006. PubMed ID: 32193207
[TBL] [Abstract][Full Text] [Related]
2. Novel Antibody Drug Conjugates Targeting Tumor-Associated Receptor Tyrosine Kinase ROR2 by Functional Screening of Fully Human Antibody Libraries Using Transpo-mAb Display on Progenitor B Cells.
Hellmann I; Waldmeier L; Bannwarth-Escher MC; Maslova K; Wolter FI; Grawunder U; Beerli RR
Front Immunol; 2018; 9():2490. PubMed ID: 30450096
[TBL] [Abstract][Full Text] [Related]
3. Potent and selective antitumor activity of a T cell-engaging bispecific antibody targeting a membrane-proximal epitope of ROR1.
Qi J; Li X; Peng H; Cook EM; Dadashian EL; Wiestner A; Park H; Rader C
Proc Natl Acad Sci U S A; 2018 Jun; 115(24):E5467-E5476. PubMed ID: 29844189
[TBL] [Abstract][Full Text] [Related]
4. Humanization of rabbit monoclonal antibodies via grafting combined Kabat/IMGT/Paratome complementarity-determining regions: Rationale and examples.
Zhang YF; Ho M
MAbs; 2017 Apr; 9(3):419-429. PubMed ID: 28165915
[TBL] [Abstract][Full Text] [Related]
5. ROR1 and ROR2-novel targets for neuroblastoma.
Dave H; Butcher D; Anver M; Bollard CM
Pediatr Hematol Oncol; 2019 Sep; 36(6):352-364. PubMed ID: 31441359
[No Abstract] [Full Text] [Related]
6. Mining Naïve Rabbit Antibody Repertoires by Phage Display for Monoclonal Antibodies of Therapeutic Utility.
Peng H; Nerreter T; Chang J; Qi J; Li X; Karunadharma P; Martinez GJ; Fallahi M; Soden J; Freeth J; Beerli RR; Grawunder U; Hudecek M; Rader C
J Mol Biol; 2017 Sep; 429(19):2954-2973. PubMed ID: 28818634
[TBL] [Abstract][Full Text] [Related]
7. Antibody humanization by redesign of complementarity-determining region residues proximate to the acceptor framework.
Hanf KJ; Arndt JW; Chen LL; Jarpe M; Boriack-Sjodin PA; Li Y; van Vlijmen HW; Pepinsky RB; Simon KJ; Lugovskoy A
Methods; 2014 Jan; 65(1):68-76. PubMed ID: 23816785
[TBL] [Abstract][Full Text] [Related]
8. Therapeutic potential and challenges of targeting receptor tyrosine kinase ROR1 with monoclonal antibodies in B-cell malignancies.
Yang J; Baskar S; Kwong KY; Kennedy MG; Wiestner A; Rader C
PLoS One; 2011; 6(6):e21018. PubMed ID: 21698301
[TBL] [Abstract][Full Text] [Related]
9. Humanized Affinity-matured Monoclonal Antibody 8H9 Has Potent Antitumor Activity and Binds to FG Loop of Tumor Antigen B7-H3.
Ahmed M; Cheng M; Zhao Q; Goldgur Y; Cheal SM; Guo HF; Larson SM; Cheung NK
J Biol Chem; 2015 Dec; 290(50):30018-29. PubMed ID: 26487718
[TBL] [Abstract][Full Text] [Related]
10. Crystal structure of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (hROR1).
Guarino SR; Di Bello A; Palamini M; Capillo MC; Forneris F
Acta Crystallogr F Struct Biol Commun; 2022 May; 78(Pt 5):185-192. PubMed ID: 35506763
[TBL] [Abstract][Full Text] [Related]
11. Affinity Maturation of Monoclonal Antibody 1E11 by Targeted Randomization in CDR3 Regions Optimizes Therapeutic Antibody Targeting of HER2-Positive Gastric Cancer.
Ko BK; Choi S; Cui LG; Lee YH; Hwang IS; Kim KT; Shim H; Lee JS
PLoS One; 2015; 10(7):e0134600. PubMed ID: 26225765
[TBL] [Abstract][Full Text] [Related]
12. Humanization of a murine monoclonal antibody by simultaneous optimization of framework and CDR residues.
Wu H; Nie Y; Huse WD; Watkins JD
J Mol Biol; 1999 Nov; 294(1):151-62. PubMed ID: 10556035
[TBL] [Abstract][Full Text] [Related]
13. Purification and characterization of the extracellular region of human receptor tyrosine kinase like orphan receptor 2 (ROR2).
Li Y; Han X; Xu W; Rao Z; Li X
Protein Expr Purif; 2019 Jun; 158():74-80. PubMed ID: 30826310
[TBL] [Abstract][Full Text] [Related]
14. Structural insights into humanization of anti-tissue factor antibody 10H10.
Teplyakov A; Obmolova G; Malia TJ; Raghunathan G; Martinez C; Fransson J; Edwards W; Connor J; Husovsky M; Beck H; Chi E; Fenton S; Zhou H; Almagro JC; Gilliland GL
MAbs; 2018; 10(2):269-277. PubMed ID: 29283291
[TBL] [Abstract][Full Text] [Related]
15. Structure guided maturation of a novel humanized anti-HBV antibody and its preclinical development.
Zhou B; Xia L; Zhang T; You M; Huang Y; He M; Su R; Tang J; Zhang J; Li S; An Z; Yuan Q; Luo W; Xia N
Antiviral Res; 2020 Aug; 180():104757. PubMed ID: 32171857
[TBL] [Abstract][Full Text] [Related]
16. Antibody humanization by structure-based computational protein design.
Choi Y; Hua C; Sentman CL; Ackerman ME; Bailey-Kellogg C
MAbs; 2015; 7(6):1045-57. PubMed ID: 26252731
[TBL] [Abstract][Full Text] [Related]
17. Generation and characterization of humanized affinity-matured EGFL6 antibodies for ovarian cancer therapy.
Tang H; Fayomi AP; Bai S; Gupta N; Cascio S; Yang D; Buckanovich RJ
Gynecol Oncol; 2023 Apr; 171():49-58. PubMed ID: 36804621
[TBL] [Abstract][Full Text] [Related]
18. The rabbit antibody repertoire as a novel source for the generation of therapeutic human antibodies.
Rader C; Ritter G; Nathan S; Elia M; Gout I; Jungbluth AA; Cohen LS; Welt S; Old LJ; Barbas CF
J Biol Chem; 2000 May; 275(18):13668-76. PubMed ID: 10788485
[TBL] [Abstract][Full Text] [Related]
19. Development of an affinity-matured humanized anti-epidermal growth factor receptor antibody for cancer immunotherapy.
Nakanishi T; Maru T; Tahara K; Sanada H; Umetsu M; Asano R; Kumagai I
Protein Eng Des Sel; 2013 Feb; 26(2):113-22. PubMed ID: 23118340
[TBL] [Abstract][Full Text] [Related]
20. Wnt5a induces ROR1/ROR2 heterooligomerization to enhance leukemia chemotaxis and proliferation.
Yu J; Chen L; Cui B; Widhopf GF; Shen Z; Wu R; Zhang L; Zhang S; Briggs SP; Kipps TJ
J Clin Invest; 2016 Feb; 126(2):585-98. PubMed ID: 26690702
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
