These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

271 related articles for article (PubMed ID: 32197094)

  • 1. A Preclinical Candidate Targeting Mycobacterium tuberculosis KasA.
    Inoyama D; Awasthi D; Capodagli GC; Tsotetsi K; Sukheja P; Zimmerman M; Li SG; Jadhav R; Russo R; Wang X; Grady C; Richmann T; Shrestha R; Li L; Ahn YM; Ho Liang HP; Mina M; Park S; Perlin DS; Connell N; Dartois V; Alland D; Neiditch MB; Kumar P; Freundlich JS
    Cell Chem Biol; 2020 May; 27(5):560-570.e10. PubMed ID: 32197094
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synergistic Lethality of a Binary Inhibitor of Mycobacterium tuberculosis KasA.
    Kumar P; Capodagli GC; Awasthi D; Shrestha R; Maharaja K; Sukheja P; Li SG; Inoyama D; Zimmerman M; Ho Liang HP; Sarathy J; Mina M; Rasic G; Russo R; Perryman AL; Richmann T; Gupta A; Singleton E; Verma S; Husain S; Soteropoulos P; Wang Z; Morris R; Porter G; Agnihotri G; Salgame P; Ekins S; Rhee KY; Connell N; Dartois V; Neiditch MB; Freundlich JS; Alland D
    mBio; 2018 Dec; 9(6):. PubMed ID: 30563908
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Isoniazid affects multiple components of the type II fatty acid synthase system of Mycobacterium tuberculosis.
    Slayden RA; Lee RE; Barry CE
    Mol Microbiol; 2000 Nov; 38(3):514-25. PubMed ID: 11069675
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of a Mycobacterium tuberculosis beta-ketoacyl ACP synthase by isoniazid.
    Mdluli K; Slayden RA; Zhu Y; Ramaswamy S; Pan X; Mead D; Crane DD; Musser JM; Barry CE
    Science; 1998 Jun; 280(5369):1607-10. PubMed ID: 9616124
    [TBL] [Abstract][Full Text] [Related]  

  • 5.
    Rudraraju RS; Daher SS; Gallardo-Macias R; Wang X; Neiditch MB; Freundlich JS
    Front Cell Infect Microbiol; 2022; 12():1008213. PubMed ID: 36189349
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The β-ketoacyl-ACP synthase from Mycobacterium tuberculosis as potential drug targets.
    Singh V; Mani I; Chaudhary DK; Somvanshi P
    Curr Med Chem; 2011; 18(9):1318-24. PubMed ID: 21370994
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Thiolactomycin-based β-ketoacyl-AcpM synthase A (KasA) inhibitors: fragment-based inhibitor discovery using transient one-dimensional nuclear overhauser effect NMR spectroscopy.
    Kapilashrami K; Bommineni GR; Machutta CA; Kim P; Lai CT; Simmerling C; Picart F; Tonge PJ
    J Biol Chem; 2013 Mar; 288(9):6045-52. PubMed ID: 23306195
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of KasA as the cellular target of an anti-tubercular scaffold.
    Abrahams KA; Chung CW; Ghidelli-Disse S; Rullas J; Rebollo-López MJ; Gurcha SS; Cox JA; Mendoza A; Jiménez-Navarro E; Martínez-Martínez MS; Neu M; Shillings A; Homes P; Argyrou A; Casanueva R; Loman NJ; Moynihan PJ; Lelièvre J; Selenski C; Axtman M; Kremer L; Bantscheff M; Angulo-Barturen I; Izquierdo MC; Cammack NC; Drewes G; Ballell L; Barros D; Besra GS; Bates RH
    Nat Commun; 2016 Sep; 7():12581. PubMed ID: 27581223
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG and M. tuberculosis.
    Larsen MH; Vilchèze C; Kremer L; Besra GS; Parsons L; Salfinger M; Heifets L; Hazbon MH; Alland D; Sacchettini JC; Jacobs WR
    Mol Microbiol; 2002 Oct; 46(2):453-66. PubMed ID: 12406221
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular dynamics of Mycobacterium tuberculosis KasA: implications for inhibitor and substrate binding and consequences for drug design.
    Schaefer B; Kisker C; Sotriffer CA
    J Comput Aided Mol Des; 2011 Nov; 25(11):1053-69. PubMed ID: 22076471
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Purification and biochemical characterization of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthases KasA and KasB.
    Schaeffer ML; Agnihotri G; Volker C; Kallender H; Brennan PJ; Lonsdale JT
    J Biol Chem; 2001 Dec; 276(50):47029-37. PubMed ID: 11600501
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In Silico Drug Design of Thiolactomycin Derivatives Against Mtb-KasA Enzyme to Inhibit Multidrug Resistance of Mycobacterium tuberculosis.
    Durairaj DR; Shanmughavel P
    Interdiscip Sci; 2019 Jun; 11(2):215-225. PubMed ID: 28856604
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Contribution of kasA analysis to detection of isoniazid-resistant Mycobacterium tuberculosis in Singapore.
    Lee AS; Lim IH; Tang LL; Telenti A; Wong SY
    Antimicrob Agents Chemother; 1999 Aug; 43(8):2087-9. PubMed ID: 10428945
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Elucidation of the protonation states of the catalytic residues in mtKasA: implications for inhibitor design.
    Lee W; Luckner SR; Kisker C; Tonge PJ; Engels B
    Biochemistry; 2011 Jun; 50(25):5743-56. PubMed ID: 21615093
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Exploring the SAR of the β-Ketoacyl-ACP Synthase Inhibitor GSK3011724A and Optimization around a Genotoxic Metabolite.
    Cunningham F; Esquivias J; Fernández-Menéndez R; Pérez A; Guardia A; Escribano J; Rivero C; Vimal M; Cacho M; de Dios-Antón P; Martínez-Martínez MS; Jiménez E; Huertas Valentín L; Rebollo-López MJ; López-Román EM; Sousa-Morcuende V; Rullas J; Neu M; Chung CW; Bates RH
    ACS Infect Dis; 2020 May; 6(5):1098-1109. PubMed ID: 32196311
    [TBL] [Abstract][Full Text] [Related]  

  • 16.
    Borthwick JA; Alemparte C; Wall I; Whitehurst BC; Argyrou A; Burley G; de Dios-Anton P; Guijarro L; Monteiro MC; Ortega F; Suckling CJ; Pichel JC; Cacho M; Young RJ
    J Med Chem; 2020 Mar; 63(5):2557-2576. PubMed ID: 31922409
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Analysis of the role of Mycobacterium tuberculosis kasA gene mutations in isoniazid resistance.
    Sun YJ; Lee AS; Wong SY; Paton NI
    Clin Microbiol Infect; 2007 Aug; 13(8):833-5. PubMed ID: 17501974
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure based virtual screening and discovery of novel inhibitors against FabD protein of
    Sundararajan S; Karunakaran K; Muniyan R
    J Biomol Struct Dyn; 2024 Aug; 42(12):6280-6291. PubMed ID: 37424186
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of InhA activity, but not KasA activity, induces formation of a KasA-containing complex in mycobacteria.
    Kremer L; Dover LG; Morbidoni HR; Vilchèze C; Maughan WN; Baulard A; Tu SC; Honoré N; Deretic V; Sacchettini JC; Locht C; Jacobs WR; Besra GS
    J Biol Chem; 2003 Jun; 278(23):20547-54. PubMed ID: 12654922
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibitors of the Thioesterase Activity of
    Krieger IV; Yalamanchili S; Dickson P; Engelhart CA; Zimmerman MD; Wood J; Clary E; Nguyen J; Thornton N; Centrella PA; Chan B; Cuozzo JW; Gengenbacher M; Guié MA; Guilinger JP; Bienstock C; Hartl H; Hupp CD; Jetson R; Satoh T; Yeoman JTS; Zhang Y; Dartois V; Schnappinger D; Keefe AD; Sacchettini JC
    ACS Infect Dis; 2024 May; 10(5):1561-1575. PubMed ID: 38577994
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.