BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 32205046)

  • 1. Small molecule inhibitors of IκB kinase β: A chip-based screening and molecular docking simulation.
    Cho YW; Lim HJ; Han MH; Kim BC; Han S
    Bioorg Med Chem; 2020 May; 28(9):115440. PubMed ID: 32205046
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis, and biological evaluation of novel
    Xie X; Tu J; You H; Hu B
    Drug Des Devel Ther; 2017; 11():1439-1451. PubMed ID: 28553074
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The small-molecule inhibitor selectivity between IKKα and IKKβ kinases in NF-κB signaling pathway.
    Tian F; Zhou P; Kang W; Luo L; Fan X; Yan J; Liang H
    J Recept Signal Transduct Res; 2015; 35(4):307-18. PubMed ID: 25386663
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Computational design and discovery of nanomolar inhibitors of IκB kinase β.
    Park H; Shin Y; Choe H; Hong S
    J Am Chem Soc; 2015 Jan; 137(1):337-48. PubMed ID: 25513719
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Small molecule binding to inhibitor of nuclear factor kappa-B kinase subunit beta in an ATP non-competitive manner.
    Napoleon JV; Singh S; Rana S; Bendjennat M; Kumar V; Kizhake S; Palermo NY; Ouellette MM; Huxford T; Natarajan A
    Chem Commun (Camb); 2021 May; 57(38):4678-4681. PubMed ID: 33977973
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of thienopyrimidine-based FLT3 inhibitors from the structural modification of known IKKβ inhibitors.
    Park CH; Lee C; Yang JS; Joe BY; Chun K; Kim H; Kim HY; Kang JS; Lee JI; Kim MH; Han G
    Bioorg Med Chem Lett; 2014 Jun; 24(12):2655-60. PubMed ID: 24813730
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of IKKβ by celastrol and its analogues - an in silico and in vitro approach.
    Veerappan K; Natarajan S; Ethiraj P; Vetrivel U; Samuel S
    Pharm Biol; 2017 Dec; 55(1):368-373. PubMed ID: 27931154
    [TBL] [Abstract][Full Text] [Related]  

  • 8. IKKbeta inhibitors identification part I: homology model assisted structure based virtual screening.
    Nagarajan S; Doddareddy Mr; Choo H; Cho YS; Oh KS; Lee BH; Pae AN
    Bioorg Med Chem; 2009 Apr; 17(7):2759-66. PubMed ID: 19285872
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pentacyclic Triterpenoids Inhibit IKKβ Mediated Activation of NF-κB Pathway: In Silico and In Vitro Evidences.
    Patil KR; Mohapatra P; Patel HM; Goyal SN; Ojha S; Kundu CN; Patil CR
    PLoS One; 2015; 10(5):e0125709. PubMed ID: 25938234
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel IKKβ inhibitors discovery based on the co-crystal structure by using binding-conformation-based and ligand-based method.
    Huang JJ; Wu XW; Jia JM; Guo XK; Xue X; Jiang ZY; Zhang SL; Zhang XJ; Sun HP; You QD
    Eur J Med Chem; 2013 May; 63():269-78. PubMed ID: 23501112
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel non-peptide small molecules preventing IKKβ/NEMO association inhibit NF-κB activation in LPS-stimulated J774 macrophages.
    De Falco F; Di Giovanni C; Cerchia C; De Stefano D; Capuozzo A; Irace C; Iuvone T; Santamaria R; Carnuccio R; Lavecchia A
    Biochem Pharmacol; 2016 Mar; 104():83-94. PubMed ID: 26776306
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Adamantyl arotinoids that inhibit IκB kinase α and IκB kinase β.
    Lorenzo P; Ortiz MA; Alvarez R; Piedrafita FJ; de Lera AR
    ChemMedChem; 2013 Jul; 8(7):1184-98. PubMed ID: 23653373
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of novel pyruvate dehydrogenase kinases inhibitors by screening of an in-house small molecule library for anti-lung cancer therapeutics.
    Guo F; Zhao S; Li X
    Bioorg Med Chem Lett; 2019 Jan; 29(2):291-296. PubMed ID: 30470491
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Combination of pharmacophore model development and binding mode analyses: identification of ligand features essential for IκB kinase-beta (IKKβ) inhibitors and virtual screening based on it.
    Sun HP; Zhu J; Chen FH; Zhang SL; Zhang Y; You QD
    Eur J Med Chem; 2011 Sep; 46(9):3942-52. PubMed ID: 21708416
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In silico drug design of inhibitor of nuclear factor kappa B kinase subunit beta inhibitors from 2-acylamino-3-aminothienopyridines based on quantitative structure-activity relationships and molecular docking.
    Wang JL; Li L; Hu MB; Wu B; Fan WX; Peng W; Wei DN; Wu CJ
    Comput Biol Chem; 2019 Feb; 78():297-305. PubMed ID: 30605855
    [TBL] [Abstract][Full Text] [Related]  

  • 16. IKKbeta inhibitors identification part II: ligand and structure-based virtual screening.
    Nagarajan S; Choo H; Cho YS; Oh KS; Lee BH; Shin KJ; Pae AN
    Bioorg Med Chem; 2010 Jun; 18(11):3951-60. PubMed ID: 20488717
    [TBL] [Abstract][Full Text] [Related]  

  • 17. IKKβ inhibitor identification: a multi-filter driven novel scaffold.
    Nagarajan S; Choo H; Cho YS; Shin KJ; Oh KS; Lee BH; Pae AN
    BMC Bioinformatics; 2010 Oct; 11 Suppl 7(Suppl 7):S15. PubMed ID: 21106122
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The discovery of a novel IκB kinase β inhibitor based on pharmacophore modeling, virtual screening and biological evaluation.
    Li L; Gong S
    Future Med Chem; 2024 Mar; 16(6):531-544. PubMed ID: 38385164
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Optimization study towards more potent thiazolidine-2,4-dione IKK-β modulator: Synthesis, biological evaluation and in silico docking simulation.
    Elkamhawy A; Youn Kim N; Hassan AHE; Park JE; Yang JE; Elsherbeny MH; Paik S; Oh KS; Lee BH; Lee MY; Shin KJ; Pae AN; Lee KT; Roh EJ
    Bioorg Chem; 2019 Nov; 92():103261. PubMed ID: 31542718
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of novel PI3Kδ inhibitors by docking, ADMET prediction and molecular dynamics simulations.
    Liu YY; Feng XY; Jia WQ; Jing Z; Xu WR; Cheng XC
    Comput Biol Chem; 2019 Feb; 78():190-204. PubMed ID: 30557817
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.