These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. Pathogenesis of Hypertrophic Cardiomyopathy is Mutation Rather Than Disease Specific: A Comparison of the Cardiac Troponin T E163R and R92Q Mouse Models. Ferrantini C; Coppini R; Pioner JM; Gentile F; Tosi B; Mazzoni L; Scellini B; Piroddi N; Laurino A; Santini L; Spinelli V; Sacconi L; De Tombe P; Moore R; Tardiff J; Mugelli A; Olivotto I; Cerbai E; Tesi C; Poggesi C J Am Heart Assoc; 2017 Jul; 6(7):. PubMed ID: 28735292 [TBL] [Abstract][Full Text] [Related]
5. Phospholamban ablation rescues the enhanced propensity to arrhythmias of mice with CaMKII-constitutive phosphorylation of RyR2 at site S2814. Mazzocchi G; Sommese L; Palomeque J; Felice JI; Di Carlo MN; Fainstein D; Gonzalez P; Contreras P; Skapura D; McCauley MD; Lascano EC; Negroni JA; Kranias EG; Wehrens XH; Valverde CA; Mattiazzi A J Physiol; 2016 Jun; 594(11):3005-30. PubMed ID: 26695843 [TBL] [Abstract][Full Text] [Related]
6. Desensitization of myofilaments to Ca2+ as a therapeutic target for hypertrophic cardiomyopathy with mutations in thin filament proteins. Alves ML; Dias FAL; Gaffin RD; Simon JN; Montminy EM; Biesiadecki BJ; Hinken AC; Warren CM; Utter MS; Davis RT; Sakthivel S; Robbins J; Wieczorek DF; Solaro RJ; Wolska BM Circ Cardiovasc Genet; 2014 Apr; 7(2):132-143. PubMed ID: 24585742 [TBL] [Abstract][Full Text] [Related]
7. Long-term rescue of a familial hypertrophic cardiomyopathy caused by a mutation in the thin filament protein, tropomyosin, via modulation of a calcium cycling protein. Gaffin RD; Peña JR; Alves MS; Dias FA; Chowdhury SA; Heinrich LS; Goldspink PH; Kranias EG; Wieczorek DF; Wolska BM J Mol Cell Cardiol; 2011 Nov; 51(5):812-20. PubMed ID: 21840315 [TBL] [Abstract][Full Text] [Related]
8. Mavacamten rescues increased myofilament calcium sensitivity and dysregulation of Ca Sparrow AJ; Watkins H; Daniels MJ; Redwood C; Robinson P Am J Physiol Heart Circ Physiol; 2020 Mar; 318(3):H715-H722. PubMed ID: 32083971 [TBL] [Abstract][Full Text] [Related]
9. Cardiac troponin T mutations: correlation between the type of mutation and the nature of myofilament dysfunction in transgenic mice. Montgomery DE; Tardiff JC; Chandra M J Physiol; 2001 Oct; 536(Pt 2):583-92. PubMed ID: 11600691 [TBL] [Abstract][Full Text] [Related]
10. Ablation of phospholamban rescues reperfusion arrhythmias but exacerbates myocardium infarction in hearts with Ca2+/calmodulin kinase II constitutive phosphorylation of ryanodine receptors. Valverde CA; Mazzocchi G; Di Carlo MN; Ciocci Pardo A; Salas N; Ragone MI; Felice JI; Cely-Ortiz A; Consolini AE; Portiansky E; Mosca S; Kranias EG; Wehrens XHT; Mattiazzi A Cardiovasc Res; 2019 Mar; 115(3):556-569. PubMed ID: 30169578 [TBL] [Abstract][Full Text] [Related]
11. Ca(2+) activation of myofilaments from transgenic mouse hearts expressing R92Q mutant cardiac troponin T. Chandra M; Rundell VL; Tardiff JC; Leinwand LA; De Tombe PP; Solaro RJ Am J Physiol Heart Circ Physiol; 2001 Feb; 280(2):H705-13. PubMed ID: 11158969 [TBL] [Abstract][Full Text] [Related]
15. Influence of a constitutive increase in myofilament Ca(2+)-sensitivity on Ca(2+)-fluxes and contraction of mouse heart ventricular myocytes. Puglisi JL; Goldspink PH; Gomes AV; Utter MS; Bers DM; Solaro RJ Arch Biochem Biophys; 2014 Jun; 552-553():50-9. PubMed ID: 24480308 [TBL] [Abstract][Full Text] [Related]
16. Differential effect of troponin T mutations on the inotropic responsiveness of mouse hearts--role of myofilament Ca2+ sensitivity increase. Sirenko SG; Potter JD; Knollmann BC J Physiol; 2006 Aug; 575(Pt 1):201-13. PubMed ID: 16777946 [TBL] [Abstract][Full Text] [Related]
17. CaMKII-mediated phosphorylation of RyR2 plays a crucial role in aberrant Ca Okuda S; Sufu-Shimizu Y; Kato T; Fukuda M; Nishimura S; Oda T; Kobayashi S; Yamamoto T; Morimoto S; Yano M Biochem Biophys Res Commun; 2018 Feb; 496(4):1250-1256. PubMed ID: 29402414 [TBL] [Abstract][Full Text] [Related]
18. Increased myofilament Ca2+ sensitivity and diastolic dysfunction as early consequences of Mybpc3 mutation in heterozygous knock-in mice. Fraysse B; Weinberger F; Bardswell SC; Cuello F; Vignier N; Geertz B; Starbatty J; Krämer E; Coirault C; Eschenhagen T; Kentish JC; Avkiran M; Carrier L J Mol Cell Cardiol; 2012 Jun; 52(6):1299-307. PubMed ID: 22465693 [TBL] [Abstract][Full Text] [Related]
19. Pathogenic troponin T mutants with opposing effects on myofilament Ca Dieseldorff Jones KM; Koh Y; Weller RS; Turna RS; Ahmad F; Huke S; Knollmann BC; Pinto JR; Hwang HS Arch Biochem Biophys; 2019 Jan; 661():125-131. PubMed ID: 30445044 [TBL] [Abstract][Full Text] [Related]
20. Constitutive phosphorylation of cardiac myosin regulatory light chain prevents development of hypertrophic cardiomyopathy in mice. Yuan CC; Muthu P; Kazmierczak K; Liang J; Huang W; Irving TC; Kanashiro-Takeuchi RM; Hare JM; Szczesna-Cordary D Proc Natl Acad Sci U S A; 2015 Jul; 112(30):E4138-46. PubMed ID: 26124132 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]