150 related articles for article (PubMed ID: 32212718)
1. Discovery, Radiolabeling, and Evaluation of Subtype-Selective Inhibitors for Positron Emission Tomography Imaging of Brain Phosphodiesterase-4D.
Wakabayashi Y; Telu S; Dick RM; Fujita M; Ooms M; Morse CL; Liow JS; Hong JS; Gladding RL; Manly LS; Zoghbi SS; Mo X; D'Amato EC; Sindac JA; Nugent RA; Marron BE; Gurney ME; Innis RB; Pike VW
ACS Chem Neurosci; 2020 May; 11(9):1311-1323. PubMed ID: 32212718
[TBL] [Abstract][Full Text] [Related]
2. Robust Quantification of Phosphodiesterase-4D in Monkey Brain with PET and
Jiang M; Tang S; Jenkins MD; Lee AC; Kenou B; Knoer C; Montero Santamaria J; Wu S; Liow JS; Zoghbi SS; Zanotti-Fregonara P; Innis RB; Telu S; Pike VW
J Nucl Med; 2024 May; 65(5):788-793. PubMed ID: 38423785
[TBL] [Abstract][Full Text] [Related]
3. An Empirical Quantitative Structure-Activity Relationship Equation Assists the Discovery of High-Affinity Phosphodiesterase 4D Inhibitors as Leads to PET Radioligands.
Jiang M; Lu S; Telu S; Pike VW
J Med Chem; 2023 Jan; 66(2):1543-1561. PubMed ID: 36608175
[TBL] [Abstract][Full Text] [Related]
4. A Nonhuman Primate PET Study: Measurement of Brain PDE4 Occupancy by Roflumilast Using (R)-[
Takano A; Uz T; Garcia-Segovia J; Tsai M; Lahu G; Amini N; Nakao R; Jia Z; Halldin C
Mol Imaging Biol; 2018 Aug; 20(4):615-622. PubMed ID: 29441434
[TBL] [Abstract][Full Text] [Related]
5. PET measurement of the in vivo affinity of 11C-(R)-rolipram and the density of its target, phosphodiesterase-4, in the brains of conscious and anesthetized rats.
Itoh T; Abe K; Zoghbi SS; Inoue O; Hong J; Imaizumi M; Pike VW; Innis RB; Fujita M
J Nucl Med; 2009 May; 50(5):749-56. PubMed ID: 19372471
[TBL] [Abstract][Full Text] [Related]
6. First-in-Human Evaluation of
Wakabayashi Y; Stenkrona P; Arakawa R; Yan X; Van Buskirk MG; Jenkins MD; Santamaria JAM; Maresca KP; Takano A; Liow JS; Chappie TA; Varrone A; Nag S; Zhang L; Hughes ZA; Schmidt CJ; Doran SD; Mannes A; Zanotti-Fregonara P; Ooms M; Morse CL; Zoghbi SS; Halldin C; Pike VW; Innis RB
J Nucl Med; 2022 Dec; 63(12):1919-1924. PubMed ID: 35772961
[TBL] [Abstract][Full Text] [Related]
7. The Discovery of a Novel Phosphodiesterase (PDE) 4B-Preferring Radioligand for Positron Emission Tomography (PET) Imaging.
Zhang L; Chen L; Beck EM; Chappie TA; Coelho RV; Doran SD; Fan KH; Helal CJ; Humphrey JM; Hughes Z; Kuszpit K; Lachapelle EA; Lazzaro JT; Lee C; Mather RJ; Patel NC; Skaddan MB; Sciabola S; Verhoest PR; Young JM; Zasadny K; Villalobos A
J Med Chem; 2017 Oct; 60(20):8538-8551. PubMed ID: 28957634
[TBL] [Abstract][Full Text] [Related]
8. Memory enhancing effects of BPN14770, an allosteric inhibitor of phosphodiesterase-4D, in wild-type and humanized mice.
Zhang C; Xu Y; Chowdhary A; Fox D; Gurney ME; Zhang HT; Auerbach BD; Salvi RJ; Yang M; Li G; O'Donnell JM
Neuropsychopharmacology; 2018 Oct; 43(11):2299-2309. PubMed ID: 30131563
[TBL] [Abstract][Full Text] [Related]
9. Antidepressant-like profile and reduced sensitivity to rolipram in mice deficient in the PDE4D phosphodiesterase enzyme.
Zhang HT; Huang Y; Jin SL; Frith SA; Suvarna N; Conti M; O'Donnell JM
Neuropsychopharmacology; 2002 Oct; 27(4):587-95. PubMed ID: 12377395
[TBL] [Abstract][Full Text] [Related]
10. Quantification of human brain PDE4 occupancy by GSK356278: A [
van der Aart J; Salinas C; Dimber R; Pampols-Maso S; Weekes AA; Tonkyn J; Gray FA; Passchier J; Gunn RN; Rabiner EA
J Cereb Blood Flow Metab; 2018 Nov; 38(11):2033-2040. PubMed ID: 28737056
[TBL] [Abstract][Full Text] [Related]
11. PET measurements of cAMP-mediated phosphodiesterase-4 with (R)-[11C]rolipram.
Kenk M; Thomas A; Lortie M; Dekemp R; Beanlands RS; Dasilva JN
Curr Radiopharm; 2011 Jan; 4(1):44-58. PubMed ID: 22191614
[TBL] [Abstract][Full Text] [Related]
12. Whole-body biodistribution and radiation dosimetry in monkeys and humans of the phosphodiesterase 4 radioligand [(11)C](R)-rolipram: comparison of two-dimensional planar, bisected and quadrisected image analyses.
Sprague DR; Fujita M; Ryu YH; Liow JS; Pike VW; Innis RB
Nucl Med Biol; 2008 May; 35(4):493-500. PubMed ID: 18482687
[TBL] [Abstract][Full Text] [Related]
13. Loss of phosphodiesterase 4 in Parkinson disease: Relevance to cognitive deficits.
Niccolini F; Wilson H; Pagano G; Coello C; Mehta MA; Searle GE; Gunn RN; Rabiner EA; Foltynie T; Politis M
Neurology; 2017 Aug; 89(6):586-593. PubMed ID: 28701494
[TBL] [Abstract][Full Text] [Related]
14. Development of a Novel [
Nag S; Bolin M; Datta P; Arakawa R; Forsberg Morén A; Khani Maynaq Y; Lin E; Genung N; Hering H; Guckian K; Martarello L; Kaliszczak M; Halldin C
ACS Chem Neurosci; 2023 Jul; 14(14):2560-2568. PubMed ID: 37377046
[TBL] [Abstract][Full Text] [Related]
15. 3-Substituted 1,5-Diaryl-1 H-1,2,4-triazoles as Prospective PET Radioligands for Imaging Brain COX-1 in Monkey. Part 2: Selection and Evaluation of [
Shrestha S; Singh P; Cortes-Salva MY; Jenko KJ; Ikawa M; Kim MJ; Kobayashi M; Morse CL; Gladding RL; Liow JS; Zoghbi SS; Fujita M; Innis RB; Pike VW
ACS Chem Neurosci; 2018 Nov; 9(11):2620-2627. PubMed ID: 29792035
[TBL] [Abstract][Full Text] [Related]
16. PET of (R)-11C-rolipram binding to phosphodiesterase-4 is reproducible and sensitive to increased norepinephrine in the rat heart.
Thomas AJ; DaSilva JN; Lortie M; Renaud JM; Kenk M; Beanlands RS; deKemp RA
J Nucl Med; 2011 Feb; 52(2):263-9. PubMed ID: 21270457
[TBL] [Abstract][Full Text] [Related]
17. Increased isoform-specific phosphodiesterase 4D expression is associated with pathology and cognitive impairment in Alzheimer's disease.
Paes D; Lardenoije R; Carollo RM; Roubroeks JAY; Schepers M; Coleman P; Mastroeni D; Delvaux E; Pishva E; Lunnon K; Vanmierlo T; van den Hove D; Prickaerts J
Neurobiol Aging; 2021 Jan; 97():56-64. PubMed ID: 33157432
[TBL] [Abstract][Full Text] [Related]
18. Preclinical Evaluation of 18F-PF-05270430, a Novel PET Radioligand for the Phosphodiesterase 2A Enzyme.
Chen L; Nabulsi N; Naganawa M; Zasadny K; Skaddan MB; Zhang L; Najafzadeh S; Lin SF; Helal CJ; Boyden TL; Chang C; Ropchan J; Carson RE; Villalobos A; Huang Y
J Nucl Med; 2016 Sep; 57(9):1448-53. PubMed ID: 27199356
[TBL] [Abstract][Full Text] [Related]
19. In Vivo Evaluation of
Zhou X; Boellaard R; Ishiwata K; Sakata M; Dierckx RAJO; de Jong JR; Nishiyama S; Ohba H; Tsukada H; de Vries EFJ; Elsinga PH
J Nucl Med; 2017 May; 58(5):762-767. PubMed ID: 28062599
[No Abstract] [Full Text] [Related]
20. Characterization of r-[11C]rolipram for PET imaging of phosphodieterase-4: in vivo binding, metabolism, and dosimetry studies in rats.
Lourenco CM; Houle S; Wilson AA; DaSilva JN
Nucl Med Biol; 2001 May; 28(4):347-58. PubMed ID: 11395307
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
