699 related articles for article (PubMed ID: 32216003)
1. Pathological manifestation of the induced pluripotent stem cell-derived cortical neurons from an early-onset Alzheimer's disease patient carrying a presenilin-1 mutation (S170F).
Li L; Kim HJ; Roh JH; Kim M; Koh W; Kim Y; Heo H; Chung J; Nakanishi M; Yoon T; Hong CP; Seo SW; Na DL; Song J
Cell Prolif; 2020 Apr; 53(4):e12798. PubMed ID: 32216003
[TBL] [Abstract][Full Text] [Related]
2. Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation.
Ochalek A; Mihalik B; Avci HX; Chandrasekaran A; Téglási A; Bock I; Giudice ML; Táncos Z; Molnár K; László L; Nielsen JE; Holst B; Freude K; Hyttel P; Kobolák J; Dinnyés A
Alzheimers Res Ther; 2017 Dec; 9(1):90. PubMed ID: 29191219
[TBL] [Abstract][Full Text] [Related]
3. The First Generation of iPSC Line from a Korean Alzheimer's Disease Patient Carrying APP-V715M Mutation Exhibits a Distinct Mitochondrial Dysfunction.
Li L; Roh JH; Kim HJ; Park HJ; Kim M; Koh W; Heo H; Chang JW; Nakanishi M; Yoon T; Na DL; Song J
Exp Neurobiol; 2019 Jun; 28(3):329-336. PubMed ID: 31308793
[TBL] [Abstract][Full Text] [Related]
4. Modeling familial Alzheimer's disease with induced pluripotent stem cells.
Yagi T; Ito D; Okada Y; Akamatsu W; Nihei Y; Yoshizaki T; Yamanaka S; Okano H; Suzuki N
Hum Mol Genet; 2011 Dec; 20(23):4530-9. PubMed ID: 21900357
[TBL] [Abstract][Full Text] [Related]
5. [Modeling familial Alzheimer's disease with induced pluripotent stem cells].
Yagi T; Ito D; Okada Y; Akamatsu W; Nihei Y; Okano H; Suzuki N
Rinsho Shinkeigaku; 2012; 52(11):1134-6. PubMed ID: 23196540
[TBL] [Abstract][Full Text] [Related]
6. Presenilin-1 L166P mutant human pluripotent stem cell-derived neurons exhibit partial loss of γ-secretase activity in endogenous amyloid-β generation.
Koch P; Tamboli IY; Mertens J; Wunderlich P; Ladewig J; Stüber K; Esselmann H; Wiltfang J; Brüstle O; Walter J
Am J Pathol; 2012 Jun; 180(6):2404-16. PubMed ID: 22510327
[TBL] [Abstract][Full Text] [Related]
7. Modeling Alzheimer's Disease by Induced Pluripotent Stem Cells Carrying APP D678H Mutation.
Chang KH; Lee-Chen GJ; Huang CC; Lin JL; Chen YJ; Wei PC; Lo YS; Yao CF; Kuo MW; Chen CM
Mol Neurobiol; 2019 Jun; 56(6):3972-3983. PubMed ID: 30238389
[TBL] [Abstract][Full Text] [Related]
8. Flexible and Accurate Substrate Processing with Distinct Presenilin/γ-Secretases in Human Cortical Neurons.
Watanabe H; Imaizumi K; Cai T; Zhou Z; Tomita T; Okano H
eNeuro; 2021; 8(2):. PubMed ID: 33608391
[TBL] [Abstract][Full Text] [Related]
9. Highly pathogenic Alzheimer's disease presenilin 1 P117R mutation causes a specific increase in p53 and p21 protein levels and cell cycle dysregulation in human lymphocytes.
Bialopiotrowicz E; Szybinska A; Kuzniewska B; Buizza L; Uberti D; Kuznicki J; Wojda U
J Alzheimers Dis; 2012; 32(2):397-415. PubMed ID: 22810102
[TBL] [Abstract][Full Text] [Related]
10. Autophagy Induction by Bexarotene Promotes Mitophagy in Presenilin 1 Familial Alzheimer's Disease iPSC-Derived Neural Stem Cells.
Martín-Maestro P; Sproul A; Martinez H; Paquet D; Gerges M; Noggle S; Starkov AA
Mol Neurobiol; 2019 Dec; 56(12):8220-8236. PubMed ID: 31203573
[TBL] [Abstract][Full Text] [Related]
11. Overactive BRCA1 Affects Presenilin 1 in Induced Pluripotent Stem Cell-Derived Neurons in Alzheimer's Disease.
Wezyk M; Szybinska A; Wojsiat J; Szczerba M; Day K; Ronnholm H; Kele M; Berdynski M; Peplonska B; Fichna JP; Ilkowski J; Styczynska M; Barczak A; Zboch M; Filipek-Gliszczynska A; Bojakowski K; Skrzypczak M; Ginalski K; Kabza M; Makalowska I; Barcikowska-Kotowicz M; Wojda U; Falk A; Zekanowski C
J Alzheimers Dis; 2018; 62(1):175-202. PubMed ID: 29439343
[TBL] [Abstract][Full Text] [Related]
12. iPSC Modeling of Presenilin1 Mutation in Alzheimer's Disease with Cerebellar Ataxia.
Li L; Roh JH; Chang EH; Lee Y; Lee S; Kim M; Koh W; Chang JW; Kim HJ; Nakanishi M; Barker RA; Na DL; Song J
Exp Neurobiol; 2018 Oct; 27(5):350-364. PubMed ID: 30429645
[TBL] [Abstract][Full Text] [Related]
13. Phenotypic Variability in Autosomal Dominant Familial Alzheimer Disease due to the S170F Mutation of Presenilin-1.
Tiedt HO; Benjamin B; Niedeggen M; Lueschow A
Neurodegener Dis; 2018; 18(2-3):57-68. PubMed ID: 29466804
[TBL] [Abstract][Full Text] [Related]
14. Early-onset Alzheimer's disease with a de novo mutation in the presenilin 1 gene.
Golan MP; Styczyńska M; Jóźwiak K; Walecki J; Maruszak A; Pniewski J; Lugiewicz R; Filipek S; Zekanowski C; Barcikowska M
Exp Neurol; 2007 Dec; 208(2):264-8. PubMed ID: 17931627
[TBL] [Abstract][Full Text] [Related]
15. G206D Mutation of Presenilin-1 Reduces Pen2 Interaction, Increases Aβ42/Aβ40 Ratio and Elevates ER Ca(2+) Accumulation.
Chen WT; Hsieh YF; Huang YJ; Lin CC; Lin YT; Liu YC; Lien CC; Cheng IH
Mol Neurobiol; 2015 Dec; 52(3):1835-1849. PubMed ID: 25394380
[TBL] [Abstract][Full Text] [Related]
16. Presenilin 1 deficiency suppresses autophagy in human neural stem cells through reducing γ-secretase-independent ERK/CREB signaling.
Chong CM; Ke M; Tan Y; Huang Z; Zhang K; Ai N; Ge W; Qin D; Lu JH; Su H
Cell Death Dis; 2018 Aug; 9(9):879. PubMed ID: 30158533
[TBL] [Abstract][Full Text] [Related]
17. A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ.
Kwart D; Gregg A; Scheckel C; Murphy EA; Paquet D; Duffield M; Fak J; Olsen O; Darnell RB; Tessier-Lavigne M
Neuron; 2019 Oct; 104(2):256-270.e5. PubMed ID: 31416668
[TBL] [Abstract][Full Text] [Related]
18. Defective Transcytosis of APP and Lipoproteins in Human iPSC-Derived Neurons with Familial Alzheimer's Disease Mutations.
Woodruff G; Reyna SM; Dunlap M; Van Der Kant R; Callender JA; Young JE; Roberts EA; Goldstein LS
Cell Rep; 2016 Oct; 17(3):759-773. PubMed ID: 27732852
[TBL] [Abstract][Full Text] [Related]
19. Generation of induced pluripotent stem cells (IRMBi001-A) from an Alzheimer's disease patient carrying a G217D mutation in the PSEN1 gene.
Auboyer L; Monzo C; Wallon D; Rovelet-Lecrux A; Gabelle A; Gazagne I; Cacheux V; Lehmann S; Crozet C
Stem Cell Res; 2019 Jan; 34():101381. PubMed ID: 30677723
[TBL] [Abstract][Full Text] [Related]
20. Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease.
Steiner H; Capell A; Leimer U; Haass C
Eur Arch Psychiatry Clin Neurosci; 1999; 249(6):266-70. PubMed ID: 10653281
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
