These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 32229538)

  • 1. Characterization of Proinsulin T Cell Epitopes Restricted by Type 1 Diabetes-Associated HLA Class II Molecules.
    Ihantola EL; Ilmonen H; Kailaanmäki A; Rytkönen-Nissinen M; Azam A; Maillère B; Lindestam Arlehamn CS; Sette A; Motwani K; Seay HR; Brusko TM; Knip M; Veijola R; Toppari J; Ilonen J; Kinnunen T
    J Immunol; 2020 May; 204(9):2349-2359. PubMed ID: 32229538
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Proinsulin-specific, HLA-DQ8, and HLA-DQ8-transdimer-restricted CD4+ T cells infiltrate islets in type 1 diabetes.
    Pathiraja V; Kuehlich JP; Campbell PD; Krishnamurthy B; Loudovaris T; Coates PT; Brodnicki TC; O'Connell PJ; Kedzierska K; Rodda C; Bergman P; Hill E; Purcell AW; Dudek NL; Thomas HE; Kay TW; Mannering SI
    Diabetes; 2015 Jan; 64(1):172-82. PubMed ID: 25157096
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Proinsulin C-peptide is an autoantigen in people with type 1 diabetes.
    So M; Elso CM; Tresoldi E; Pakusch M; Pathiraja V; Wentworth JM; Harrison LC; Krishnamurthy B; Thomas HE; Rodda C; Cameron FJ; McMahon J; Kay TWH; Mannering SI
    Proc Natl Acad Sci U S A; 2018 Oct; 115(42):10732-10737. PubMed ID: 30275329
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Islet-Derived CD4 T Cells Targeting Proinsulin in Human Autoimmune Diabetes.
    Michels AW; Landry LG; McDaniel KA; Yu L; Campbell-Thompson M; Kwok WW; Jones KL; Gottlieb PA; Kappler JW; Tang Q; Roep BO; Atkinson MA; Mathews CE; Nakayama M
    Diabetes; 2017 Mar; 66(3):722-734. PubMed ID: 27920090
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of a Selective Islet Peptidome Presented by the Highest-Risk HLA-DQ8trans Molecule.
    van Lummel M; van Veelen PA; de Ru AH; Pool J; Nikolic T; Laban S; Joosten A; Drijfhout JW; Gómez-Touriño I; Arif S; Aanstoot HJ; Peakman M; Roep BO
    Diabetes; 2016 Mar; 65(3):732-41. PubMed ID: 26718497
    [TBL] [Abstract][Full Text] [Related]  

  • 6. How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
    Wang Y; Sosinowski T; Novikov A; Crawford F; White J; Jin N; Liu Z; Zou J; Neau D; Davidson HW; Nakayama M; Kwok WW; Gapin L; Marrack P; Kappler JW; Dai S
    Sci Immunol; 2019 Apr; 4(34):. PubMed ID: 30952805
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Analysis of pancreatic beta cell specific CD4+ T cells reveals a predominance of proinsulin specific cells.
    Blahnik G; Uchtenhagen H; Chow IT; Speake C; Greenbaum C; Kwok WW; James EA
    Cell Immunol; 2019 Jan; 335():68-75. PubMed ID: 30428974
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The A-chain of insulin is a hot-spot for CD4+ T cell epitopes in human type 1 diabetes.
    Mannering SI; Pang SH; Williamson NA; Naselli G; Reynolds EC; O'Brien-Simpson NM; Purcell AW; Harrison LC
    Clin Exp Immunol; 2009 May; 156(2):226-31. PubMed ID: 19292763
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Type 1 diabetes associated HLA-DQ2 and DQ8 molecules are relatively resistant to HLA-DM mediated release of invariant chain-derived CLIP peptides.
    Zhou Z; Reyes-Vargas E; Escobar H; Rudd B; Rockwood AL; Delgado JC; He X; Jensen PE
    Eur J Immunol; 2016 Apr; 46(4):834-45. PubMed ID: 26707565
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of Human CD4 T Cells Specific for a C-Peptide/C-Peptide Hybrid Insulin Peptide.
    Wiles TA; Hohenstein A; Landry LG; Dang M; Powell R; Guyer P; James EA; Nakayama M; Haskins K; Delong T; Baker RL
    Front Immunol; 2021; 12():668680. PubMed ID: 34113344
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A structural basis of T cell cross-reactivity to native and spliced self-antigens presented by HLA-DQ8.
    Tran MT; Lim JJ; Loh TJ; Mannering SI; Rossjohn J; Reid HH
    J Biol Chem; 2024 Sep; 300(9):107612. PubMed ID: 39074636
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Proinsulin-Reactive CD4 T Cells in the Islets of Type 1 Diabetes Organ Donors.
    Landry LG; Anderson AM; Russ HA; Yu L; Kent SC; Atkinson MA; Mathews CE; Michels AW; Nakayama M
    Front Endocrinol (Lausanne); 2021; 12():622647. PubMed ID: 33841327
    [TBL] [Abstract][Full Text] [Related]  

  • 13. T-cell epitopes of the La/SSB autoantigen: prediction based on the homology modeling of HLA-DQ2/DQ7 with the insulin-B peptide/HLA-DQ8 complex.
    Kosmopoulou A; Vlassi M; Stavrakoudis A; Sakarellos C; Sakarellos-Daitsiotis M
    J Comput Chem; 2006 Jul; 27(9):1033-44. PubMed ID: 16639700
    [TBL] [Abstract][Full Text] [Related]  

  • 14. T cell recognition of human pre-proinsulin peptides depends on the polymorphism at HLA DQ locus: a study using HLA DQ8 and DQ6 transgenic mice.
    Raju R; Munn SR; David CS
    Hum Immunol; 1997 Nov; 58(1):21-9. PubMed ID: 9438206
    [TBL] [Abstract][Full Text] [Related]  

  • 15. HLA-DQ8-associated T cell responses to the diabetes autoantigen phogrin (IA-2 beta) in human prediabetes.
    Kelemen K; Gottlieb PA; Putnam AL; Davidson HW; Wegmann DR; Hutton JC
    J Immunol; 2004 Mar; 172(6):3955-62. PubMed ID: 15004204
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dendritic Cells Guide Islet Autoimmunity through a Restricted and Uniquely Processed Peptidome Presented by High-Risk HLA-DR.
    van Lummel M; van Veelen PA; de Ru AH; Janssen GM; Pool J; Laban S; Joosten AM; Nikolic T; Drijfhout JW; Mearin ML; Aanstoot HJ; Peakman M; Roep BO
    J Immunol; 2016 Apr; 196(8):3253-63. PubMed ID: 26944932
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Major DQ8-restricted T-cell epitopes for human GAD65 mapped using human CD4, DQA1*0301, DQB1*0302 transgenic IA(null) NOD mice.
    Liu J; Purdy LE; Rabinovitch S; Jevnikar AM; Elliott JF
    Diabetes; 1999 Mar; 48(3):469-77. PubMed ID: 10078545
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Promiscuous binding of proinsulin peptides to Type 1 diabetes-permissive and -protective HLA class II molecules.
    Astill TP; Ellis RJ; Arif S; Tree TI; Peakman M
    Diabetologia; 2003 Apr; 46(4):496-503. PubMed ID: 12684749
    [TBL] [Abstract][Full Text] [Related]  

  • 19. GAD65- and proinsulin-specific CD4+ T-cells detected by MHC class II tetramers in peripheral blood of type 1 diabetes patients and at-risk subjects.
    Oling V; Marttila J; Ilonen J; Kwok WW; Nepom G; Knip M; Simell O; Reijonen H
    J Autoimmun; 2005 Nov; 25(3):235-43. PubMed ID: 16263242
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Differences in self-peptide binding between T1D-related susceptible and protective DR4 subtypes.
    Ge X; James EA; Reijonen H; Kwok WW
    J Autoimmun; 2011 Mar; 36(2):155-60. PubMed ID: 21257290
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.