300 related articles for article (PubMed ID: 32231343)
1. Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles.
Eaton JK; Furst L; Ruberto RA; Moosmayer D; Hilpmann A; Ryan MJ; Zimmermann K; Cai LL; Niehues M; Badock V; Kramm A; Chen S; Hillig RC; Clemons PA; Gradl S; Montagnon C; Lazarski KE; Christian S; Bajrami B; Neuhaus R; Eheim AL; Viswanathan VS; Schreiber SL
Nat Chem Biol; 2020 May; 16(5):497-506. PubMed ID: 32231343
[TBL] [Abstract][Full Text] [Related]
2. Diacylfuroxans Are Masked Nitrile Oxides That Inhibit GPX4 Covalently.
Eaton JK; Ruberto RA; Kramm A; Viswanathan VS; Schreiber SL
J Am Chem Soc; 2019 Dec; 141(51):20407-20415. PubMed ID: 31841309
[TBL] [Abstract][Full Text] [Related]
3. Structure-activity relationships of GPX4 inhibitor warheads.
Eaton JK; Furst L; Cai LL; Viswanathan VS; Schreiber SL
Bioorg Med Chem Lett; 2020 Dec; 30(23):127538. PubMed ID: 32920142
[TBL] [Abstract][Full Text] [Related]
4. Discovery of GPX4 inhibitors through FP-based high-throughput screening.
Cao Y; Wu B; Xu Y; Wang M; Wu X; Liang X; Lin J; Li Z; Lin H; Luo C; Chen S
Eur J Med Chem; 2024 Feb; 265():116044. PubMed ID: 38145603
[TBL] [Abstract][Full Text] [Related]
5. A potent GPX4 degrader to induce ferroptosis in HT1080 cells.
Song H; Liang J; Guo Y; Liu Y; Sa K; Yan G; Xu W; Xu W; Chen L; Li H
Eur J Med Chem; 2024 Feb; 265():116110. PubMed ID: 38194774
[TBL] [Abstract][Full Text] [Related]
6. Directly targeting glutathione peroxidase 4 may be more effective than disrupting glutathione on ferroptosis-based cancer therapy.
Wei Y; Lv H; Shaikh AB; Han W; Hou H; Zhang Z; Wang S; Shang P
Biochim Biophys Acta Gen Subj; 2020 Apr; 1864(4):129539. PubMed ID: 31958545
[TBL] [Abstract][Full Text] [Related]
7. Discovery of a Potent Glutathione Peroxidase 4 Inhibitor as a Selective Ferroptosis Inducer.
Xu C; Xiao Z; Wang J; Lai H; Zhang T; Guan Z; Xia M; Chen M; Ren L; He Y; Gao Y; Zhao C
J Med Chem; 2021 Sep; 64(18):13312-13326. PubMed ID: 34506134
[TBL] [Abstract][Full Text] [Related]
8. Research progress on GPX4 targeted compounds.
Li B; Cheng K; Wang T; Peng X; Xu P; Liu G; Xue D; Jiao N; Wang C
Eur J Med Chem; 2024 Aug; 274():116548. PubMed ID: 38838547
[TBL] [Abstract][Full Text] [Related]
9. Identification of a small molecule as inducer of ferroptosis and apoptosis through ubiquitination of GPX4 in triple negative breast cancer cells.
Ding Y; Chen X; Liu C; Ge W; Wang Q; Hao X; Wang M; Chen Y; Zhang Q
J Hematol Oncol; 2021 Jan; 14(1):19. PubMed ID: 33472669
[TBL] [Abstract][Full Text] [Related]
10. Targeting GPX4 in human cancer: Implications of ferroptosis induction for tackling cancer resilience.
Lee J; Roh JL
Cancer Lett; 2023 Apr; 559():216119. PubMed ID: 36893895
[TBL] [Abstract][Full Text] [Related]
11. Investigating Nonapoptotic Cell Death Using Chemical Biology Approaches.
Armenta DA; Dixon SJ
Cell Chem Biol; 2020 Apr; 27(4):376-386. PubMed ID: 32220334
[TBL] [Abstract][Full Text] [Related]
12. GPX4 and vitamin E cooperatively protect hematopoietic stem and progenitor cells from lipid peroxidation and ferroptosis.
Hu Q; Zhang Y; Lou H; Ou Z; Liu J; Duan W; Wang H; Ge Y; Min J; Wang F; Ju Z
Cell Death Dis; 2021 Jul; 12(7):706. PubMed ID: 34267193
[TBL] [Abstract][Full Text] [Related]
13. Dihydroartemisinin initiates ferroptosis in glioblastoma through GPX4 inhibition.
Yi R; Wang H; Deng C; Wang X; Yao L; Niu W; Fei M; Zhaba W
Biosci Rep; 2020 Jun; 40(6):. PubMed ID: 32452511
[TBL] [Abstract][Full Text] [Related]
14. Prospects for Anti-Tumor Mechanism and Potential Clinical Application Based on Glutathione Peroxidase 4 Mediated Ferroptosis.
Chen M; Shi Z; Sun Y; Ning H; Gu X; Zhang L
Int J Mol Sci; 2023 Jan; 24(2):. PubMed ID: 36675129
[TBL] [Abstract][Full Text] [Related]
15. Identification of a Small Molecule That Enhances Ferroptosis via Inhibition of Ferroptosis Suppressor Protein 1 (FSP1).
Yoshioka H; Kawamura T; Muroi M; Kondoh Y; Honda K; Kawatani M; Aono H; Waldmann H; Watanabe N; Osada H
ACS Chem Biol; 2022 Feb; 17(2):483-491. PubMed ID: 35128925
[TBL] [Abstract][Full Text] [Related]
16. GPX4 at the Crossroads of Lipid Homeostasis and Ferroptosis.
Forcina GC; Dixon SJ
Proteomics; 2019 Sep; 19(18):e1800311. PubMed ID: 30888116
[TBL] [Abstract][Full Text] [Related]
17. The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity.
Xu C; Sun S; Johnson T; Qi R; Zhang S; Zhang J; Yang K
Cell Rep; 2021 Jun; 35(11):109235. PubMed ID: 34133924
[TBL] [Abstract][Full Text] [Related]
18. Dauricine alleviated secondary brain injury after intracerebral hemorrhage by upregulating GPX4 expression and inhibiting ferroptosis of nerve cells.
Peng C; Fu X; Wang K; Chen L; Luo B; Huang N; Luo Y; Chen W
Eur J Pharmacol; 2022 Jan; 914():174461. PubMed ID: 34469757
[TBL] [Abstract][Full Text] [Related]
19. Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162.
Moosmayer D; Hilpmann A; Hoffmann J; Schnirch L; Zimmermann K; Badock V; Furst L; Eaton JK; Viswanathan VS; Schreiber SL; Gradl S; Hillig RC
Acta Crystallogr D Struct Biol; 2021 Feb; 77(Pt 2):237-248. PubMed ID: 33559612
[TBL] [Abstract][Full Text] [Related]
20. Glutathione peroxidase 4-dependent glutathione high-consumption drives acquired platinum chemoresistance in lung cancer-derived brain metastasis.
Liu W; Zhou Y; Duan W; Song J; Wei S; Xia S; Wang Y; Du X; Li E; Ren C; Wang W; Zhan Q; Wang Q
Clin Transl Med; 2021 Sep; 11(9):e517. PubMed ID: 34586745
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
