These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

118 related articles for article (PubMed ID: 32234506)

  • 1. Modeling of pathogenic variants of mitochondrial DNA polymerase: insight into the replication defects and implication for human disease.
    Hoyos-Gonzalez N; Trasviña-Arenas CH; Degiorgi A; Castro-Lara AY; Peralta-Castro A; Jimenez-Sandoval P; Diaz-Quezada C; Lodi T; Baruffini E; Brieba LG
    Biochim Biophys Acta Gen Subj; 2020 Jul; 1864(7):129608. PubMed ID: 32234506
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-specific roles for PolG2-DNA complexes in maintenance and replication of mitochondrial DNA.
    Wojtaszek JL; Hoff KE; Longley MJ; Kaur P; Andres SN; Wang H; Williams RS; Copeland WC
    Nucleic Acids Res; 2023 Oct; 51(18):9716-9732. PubMed ID: 37592734
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Antimutator alleles of yeast DNA polymerase gamma modulate the balance between DNA synthesis and excision.
    Foury F; Szczepanowska K
    PLoS One; 2011; 6(11):e27847. PubMed ID: 22114710
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Amino and carboxy-terminal extensions of yeast mitochondrial DNA polymerase assemble both the polymerization and exonuclease active sites.
    Trasviña-Arenas CH; Hoyos-Gonzalez N; Castro-Lara AY; Rodriguez-Hernandez A; Sanchez-Sandoval ME; Jimenez-Sandoval P; Ayala-García VM; Díaz-Quezada C; Lodi T; Baruffini E; Brieba LG
    Mitochondrion; 2019 Nov; 49():166-177. PubMed ID: 31445096
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synergistic Effects of the
    DeBalsi KL; Longley MJ; Hoff KE; Copeland WC
    J Biol Chem; 2017 Mar; 292(10):4198-4209. PubMed ID: 28154168
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Consequences of compromised mitochondrial genome integrity.
    Gustafson MA; Sullivan ED; Copeland WC
    DNA Repair (Amst); 2020 Sep; 93():102916. PubMed ID: 33087282
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Oxidative damage diminishes mitochondrial DNA polymerase replication fidelity.
    Anderson AP; Luo X; Russell W; Yin YW
    Nucleic Acids Res; 2020 Jan; 48(2):817-829. PubMed ID: 31799610
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural insight into processive human mitochondrial DNA synthesis and disease-related polymerase mutations.
    Lee YS; Kennedy WD; Yin YW
    Cell; 2009 Oct; 139(2):312-24. PubMed ID: 19837034
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A cluster of pathogenic mutations in the 3'-5' exonuclease domain of DNA polymerase gamma defines a novel module coupling DNA synthesis and degradation.
    Szczepanowska K; Foury F
    Hum Mol Genet; 2010 Sep; 19(18):3516-29. PubMed ID: 20601675
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Yeast model analysis of novel polymerase gamma variants found in patients with autosomal recessive mitochondrial disease.
    Kaliszewska M; Kruszewski J; Kierdaszuk B; Kostera-Pruszczyk A; Nojszewska M; Łusakowska A; Vizueta J; Sabat D; Lutyk D; Lower M; Piekutowska-Abramczuk D; Kaniak-Golik A; Pronicka E; Kamińska A; Bartnik E; Golik P; Tońska K
    Hum Genet; 2015 Sep; 134(9):951-66. PubMed ID: 26077851
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reduced stimulation of recombinant DNA polymerase γ and mitochondrial DNA (mtDNA) helicase by variants of mitochondrial single-stranded DNA-binding protein (mtSSB) correlates with defects in mtDNA replication in animal cells.
    Oliveira MT; Kaguni LS
    J Biol Chem; 2011 Nov; 286(47):40649-58. PubMed ID: 21953457
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In Vitro Analysis of mtDNA Replication.
    Uhler JP; Falkenberg M
    Methods Mol Biol; 2021; 2192():1-20. PubMed ID: 33230761
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MMS exposure promotes increased MtDNA mutagenesis in the presence of replication-defective disease-associated DNA polymerase γ variants.
    Stumpf JD; Copeland WC
    PLoS Genet; 2014 Oct; 10(10):e1004748. PubMed ID: 25340760
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The accessory subunit of human DNA polymerase γ is required for mitochondrial DNA maintenance and is able to stabilize the catalytic subunit.
    Do Y; Matsuda S; Inatomi T; Nakada K; Yasukawa T; Kang D
    Mitochondrion; 2020 Jul; 53():133-139. PubMed ID: 32470614
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Construction of a highly error-prone DNA polymerase for developing organelle mutation systems.
    Ji J; Day A
    Nucleic Acids Res; 2020 Dec; 48(21):11868-11879. PubMed ID: 33135056
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Polγ coordinates DNA synthesis and proofreading to ensure mitochondrial genome integrity.
    Park J; Herrmann GK; Mitchell PG; Sherman MB; Yin YW
    Nat Struct Mol Biol; 2023 Jun; 30(6):812-823. PubMed ID: 37202477
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Active site mutation in DNA polymerase gamma associated with progressive external ophthalmoplegia causes error-prone DNA synthesis.
    Ponamarev MV; Longley MJ; Nguyen D; Kunkel TA; Copeland WC
    J Biol Chem; 2002 May; 277(18):15225-8. PubMed ID: 11897778
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional analysis of mutant mitochondrial DNA polymerase proteins involved in human disease.
    Chan SS; Copeland WC
    Methods Mol Biol; 2009; 554():59-72. PubMed ID: 19513667
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Defects in mitochondrial DNA replication and human disease.
    Copeland WC
    Crit Rev Biochem Mol Biol; 2012; 47(1):64-74. PubMed ID: 22176657
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Deleterious mitochondrial DNA point mutations are overrepresented in Drosophila expressing a proofreading-defective DNA polymerase γ.
    Samstag CL; Hoekstra JG; Huang CH; Chaisson MJ; Youle RJ; Kennedy SR; Pallanck LJ
    PLoS Genet; 2018 Nov; 14(11):e1007805. PubMed ID: 30452458
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.