391 related articles for article (PubMed ID: 32241913)
1. Quantification of the affinities of CRISPR-Cas9 nucleases for cognate protospacer adjacent motif (PAM) sequences.
Mekler V; Kuznedelov K; Severinov K
J Biol Chem; 2020 May; 295(19):6509-6517. PubMed ID: 32241913
[TBL] [Abstract][Full Text] [Related]
2. Developing Heritable Mutations in Arabidopsis thaliana Using a Modified CRISPR/Cas9 Toolkit Comprising PAM-Altered Cas9 Variants and gRNAs.
Yamamoto A; Ishida T; Yoshimura M; Kimura Y; Sawa S
Plant Cell Physiol; 2019 Oct; 60(10):2255-2262. PubMed ID: 31198958
[TBL] [Abstract][Full Text] [Related]
3. Engineered CRISPR-Cas9 nucleases with altered PAM specificities.
Kleinstiver BP; Prew MS; Tsai SQ; Topkar VV; Nguyen NT; Zheng Z; Gonzales AP; Li Z; Peterson RT; Yeh JR; Aryee MJ; Joung JK
Nature; 2015 Jul; 523(7561):481-5. PubMed ID: 26098369
[TBL] [Abstract][Full Text] [Related]
4. Molecular Mechanism of D1135E-Induced Discriminated CRISPR-Cas9 PAM Recognition.
Kang M; Zuo Z; Yin Z; Gu J
J Chem Inf Model; 2022 Jun; 62(12):3057-3066. PubMed ID: 35666156
[TBL] [Abstract][Full Text] [Related]
5. Crystal Structure of Staphylococcus aureus Cas9.
Nishimasu H; Cong L; Yan WX; Ran FA; Zetsche B; Li Y; Kurabayashi A; Ishitani R; Zhang F; Nureki O
Cell; 2015 Aug; 162(5):1113-26. PubMed ID: 26317473
[TBL] [Abstract][Full Text] [Related]
6. Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9.
Hirano S; Nishimasu H; Ishitani R; Nureki O
Mol Cell; 2016 Mar; 61(6):886-94. PubMed ID: 26990991
[TBL] [Abstract][Full Text] [Related]
7. Structural insights into a high fidelity variant of SpCas9.
Guo M; Ren K; Zhu Y; Tang Z; Wang Y; Zhang B; Huang Z
Cell Res; 2019 Mar; 29(3):183-192. PubMed ID: 30664728
[TBL] [Abstract][Full Text] [Related]
8. Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease.
Chen W; Zhang H; Zhang Y; Wang Y; Gan J; Ji Q
PLoS Biol; 2019 Oct; 17(10):e3000496. PubMed ID: 31603896
[TBL] [Abstract][Full Text] [Related]
9. SaCas9 Requires 5'-NNGRRT-3' PAM for Sufficient Cleavage and Possesses Higher Cleavage Activity than SpCas9 or FnCpf1 in Human Cells.
Xie H; Tang L; He X; Liu X; Zhou C; Liu J; Ge X; Li J; Liu C; Zhao J; Qu J; Song Z; Gu F
Biotechnol J; 2018 Apr; 13(4):e1700561. PubMed ID: 29247600
[TBL] [Abstract][Full Text] [Related]
10. Electronic Circular Dichroism of the Cas9 Protein and gRNA:Cas9 Ribonucleoprotein Complex.
Halat M; Klimek-Chodacka M; Orleanska J; Baranska M; Baranski R
Int J Mol Sci; 2021 Mar; 22(6):. PubMed ID: 33805827
[TBL] [Abstract][Full Text] [Related]
11. CRISPR/Cas9 gRNA activity depends onĀ free energy changes and on the target PAM context.
Corsi GI; Qu K; Alkan F; Pan X; Luo Y; Gorodkin J
Nat Commun; 2022 May; 13(1):3006. PubMed ID: 35637227
[TBL] [Abstract][Full Text] [Related]
12. Superior Fidelity and Distinct Editing Outcomes of SaCas9 Compared with SpCas9 in Genome Editing.
Yang ZX; Fu YW; Zhao JJ; Zhang F; Li SA; Zhao M; Wen W; Zhang L; Cheng T; Zhang JP; Zhang XB
Genomics Proteomics Bioinformatics; 2023 Dec; 21(6):1206-1220. PubMed ID: 36549468
[TBL] [Abstract][Full Text] [Related]
13. Highly specific targeted mutagenesis in plants using Staphylococcus aureus Cas9.
Kaya H; Mikami M; Endo A; Endo M; Toki S
Sci Rep; 2016 May; 6():26871. PubMed ID: 27226350
[TBL] [Abstract][Full Text] [Related]
14. Structure and Engineering of Francisella novicida Cas9.
Hirano H; Gootenberg JS; Horii T; Abudayyeh OO; Kimura M; Hsu PD; Nakane T; Ishitani R; Hatada I; Zhang F; Nishimasu H; Nureki O
Cell; 2016 Feb; 164(5):950-61. PubMed ID: 26875867
[TBL] [Abstract][Full Text] [Related]
15. Prediction and Validation of Native and Engineered Cas9 Guide Sequences.
Briner AE; Henriksen ED; Barrangou R
Cold Spring Harb Protoc; 2016 Jul; 2016(7):. PubMed ID: 27371591
[TBL] [Abstract][Full Text] [Related]
16. Mechanism of duplex DNA destabilization by RNA-guided Cas9 nuclease during target interrogation.
Mekler V; Minakhin L; Severinov K
Proc Natl Acad Sci U S A; 2017 May; 114(21):5443-5448. PubMed ID: 28484024
[TBL] [Abstract][Full Text] [Related]
17. Programming PAM antennae for efficient CRISPR-Cas9 DNA editing.
Wang F; Hao Y; Li Q; Li J; Zhang H; Zhang X; Wang L; Bustamante C; Fan C
Sci Adv; 2020 May; 6(19):eaay9948. PubMed ID: 32494703
[TBL] [Abstract][Full Text] [Related]
18. Structural Plasticity of PAM Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9.
Anders C; Bargsten K; Jinek M
Mol Cell; 2016 Mar; 61(6):895-902. PubMed ID: 26990992
[TBL] [Abstract][Full Text] [Related]
19. CRISPR-Cas "Non-Target" Sites Inhibit On-Target Cutting Rates.
Moreb EA; Hutmacher M; Lynch MD
CRISPR J; 2020 Dec; 3(6):550-561. PubMed ID: 33346713
[TBL] [Abstract][Full Text] [Related]
20. Genome editing in plants by engineered CRISPR-Cas9 recognizing NG PAM.
Endo M; Mikami M; Endo A; Kaya H; Itoh T; Nishimasu H; Nureki O; Toki S
Nat Plants; 2019 Jan; 5(1):14-17. PubMed ID: 30531939
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]