BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

344 related articles for article (PubMed ID: 32242220)

  • 1. DUX4 expressing immortalized FSHD lymphoblastoid cells express genes elevated in FSHD muscle biopsies, correlating with the early stages of inflammation.
    Banerji CRS; Panamarova M; Zammit PS
    Hum Mol Genet; 2020 Aug; 29(14):2285-2299. PubMed ID: 32242220
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PAX7 target gene repression is a superior FSHD biomarker than DUX4 target gene activation, associating with pathological severity and identifying FSHD at the single-cell level.
    Banerji CRS; Zammit PS
    Hum Mol Genet; 2019 Jul; 28(13):2224-2236. PubMed ID: 31067297
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MRI-informed muscle biopsies correlate MRI with pathology and DUX4 target gene expression in FSHD.
    Wang LH; Friedman SD; Shaw D; Snider L; Wong CJ; Budech CB; Poliachik SL; Gove NE; Lewis LM; Campbell AE; Lemmers RJFL; Maarel SM; Tapscott SJ; Tawil RN
    Hum Mol Genet; 2019 Feb; 28(3):476-486. PubMed ID: 30312408
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Facioscapulohumeral dystrophy transcriptome signatures correlate with different stages of disease and are marked by different MRI biomarkers.
    van den Heuvel A; Lassche S; Mul K; Greco A; San León Granado D; Heerschap A; Küsters B; Tapscott SJ; Voermans NC; van Engelen BGM; van der Maarel SM
    Sci Rep; 2022 Jan; 12(1):1426. PubMed ID: 35082321
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PAX7 target gene repression associates with FSHD progression and pathology over 1 year.
    Banerji CRS
    Hum Mol Genet; 2020 Aug; 29(13):2124-2133. PubMed ID: 32347924
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PAX7 target genes are globally repressed in facioscapulohumeral muscular dystrophy skeletal muscle.
    Banerji CRS; Panamarova M; Hebaishi H; White RB; Relaix F; Severini S; Zammit PS
    Nat Commun; 2017 Dec; 8(1):2152. PubMed ID: 29255294
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Facioscapulohumeral dystrophy: incomplete suppression of a retrotransposed gene.
    Snider L; Geng LN; Lemmers RJ; Kyba M; Ware CB; Nelson AM; Tawil R; Filippova GN; van der Maarel SM; Tapscott SJ; Miller DG
    PLoS Genet; 2010 Oct; 6(10):e1001181. PubMed ID: 21060811
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DUX4-induced gene expression is the major molecular signature in FSHD skeletal muscle.
    Yao Z; Snider L; Balog J; Lemmers RJ; Van Der Maarel SM; Tawil R; Tapscott SJ
    Hum Mol Genet; 2014 Oct; 23(20):5342-52. PubMed ID: 24861551
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Longitudinal measures of RNA expression and disease activity in FSHD muscle biopsies.
    Wong CJ; Wang LH; Friedman SD; Shaw D; Campbell AE; Budech CB; Lewis LM; Lemmers RJFL; Statland JM; van der Maarel SM; Tawil RN; Tapscott SJ
    Hum Mol Genet; 2020 Apr; 29(6):1030-1043. PubMed ID: 32083293
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Facioscapulohumeral muscular dystrophy family studies of DUX4 expression: evidence for disease modifiers and a quantitative model of pathogenesis.
    Jones TI; Chen JC; Rahimov F; Homma S; Arashiro P; Beermann ML; King OD; Miller JB; Kunkel LM; Emerson CP; Wagner KR; Jones PL
    Hum Mol Genet; 2012 Oct; 21(20):4419-30. PubMed ID: 22798623
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Direct interplay between two candidate genes in FSHD muscular dystrophy.
    Ferri G; Huichalaf CH; Caccia R; Gabellini D
    Hum Mol Genet; 2015 Mar; 24(5):1256-66. PubMed ID: 25326393
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transgenic mice expressing tunable levels of DUX4 develop characteristic facioscapulohumeral muscular dystrophy-like pathophysiology ranging in severity.
    Jones TI; Chew GL; Barraza-Flores P; Schreier S; Ramirez M; Wuebbles RD; Burkin DJ; Bradley RK; Jones PL
    Skelet Muscle; 2020 Apr; 10(1):8. PubMed ID: 32278354
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Single-cell RNA sequencing in facioscapulohumeral muscular dystrophy disease etiology and development.
    van den Heuvel A; Mahfouz A; Kloet SL; Balog J; van Engelen BGM; Tawil R; Tapscott SJ; van der Maarel SM
    Hum Mol Genet; 2019 Apr; 28(7):1064-1075. PubMed ID: 30445587
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Overexpression of the double homeodomain protein DUX4c interferes with myofibrillogenesis and induces clustering of myonuclei.
    Vanderplanck C; Tassin A; Ansseau E; Charron S; Wauters A; Lancelot C; Vancutsem K; Laoudj-Chenivesse D; Belayew A; Coppée F
    Skelet Muscle; 2018 Jan; 8(1):2. PubMed ID: 29329560
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A patient-derived iPSC model revealed oxidative stress increases facioscapulohumeral muscular dystrophy-causative DUX4.
    Sasaki-Honda M; Jonouchi T; Arai M; Hotta A; Mitsuhashi S; Nishino I; Matsuda R; Sakurai H
    Hum Mol Genet; 2018 Dec; 27(23):4024-4035. PubMed ID: 30107443
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DUX4-induced constitutive DNA damage and oxidative stress contribute to aberrant differentiation of myoblasts from FSHD patients.
    Dmitriev P; Bou Saada Y; Dib C; Ansseau E; Barat A; Hamade A; Dessen P; Robert T; Lazar V; Louzada RAN; Dupuy C; Zakharova V; Carnac G; Lipinski M; Vassetzky YS
    Free Radic Biol Med; 2016 Oct; 99():244-258. PubMed ID: 27519269
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Gene expression during normal and FSHD myogenesis.
    Tsumagari K; Chang SC; Lacey M; Baribault C; Chittur SV; Sowden J; Tawil R; Crawford GE; Ehrlich M
    BMC Med Genomics; 2011 Sep; 4():67. PubMed ID: 21951698
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Skeletal muscle regeneration in facioscapulohumeral muscular dystrophy is correlated with pathological severity.
    Banerji CRS; Henderson D; Tawil RN; Zammit PS
    Hum Mol Genet; 2020 Sep; 29(16):2746-2760. PubMed ID: 32744322
    [TBL] [Abstract][Full Text] [Related]  

  • 19. p38
    Rojas LA; Valentine E; Accorsi A; Maglio J; Shen N; Robertson A; Kazmirski S; Rahl P; Tawil R; Cadavid D; Thompson LA; Ronco L; Chang AN; Cacace AM; Wallace O
    J Pharmacol Exp Ther; 2020 Sep; 374(3):489-498. PubMed ID: 32576599
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DUX4 and DUX4 downstream target genes are expressed in fetal FSHD muscles.
    Ferreboeuf M; Mariot V; Bessières B; Vasiljevic A; Attié-Bitach T; Collardeau S; Morere J; Roche S; Magdinier F; Robin-Ducellier J; Rameau P; Whalen S; Desnuelle C; Sacconi S; Mouly V; Butler-Browne G; Dumonceaux J
    Hum Mol Genet; 2014 Jan; 23(1):171-81. PubMed ID: 23966205
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.