406 related articles for article (PubMed ID: 32243837)
1. KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer.
Alam H; Tang M; Maitituoheti M; Dhar SS; Kumar M; Han CY; Ambati CR; Amin SB; Gu B; Chen TY; Lin YH; Chen J; Muller FL; Putluri N; Flores ER; DeMayo FJ; Baseler L; Rai K; Lee MG
Cancer Cell; 2020 Apr; 37(4):599-617.e7. PubMed ID: 32243837
[TBL] [Abstract][Full Text] [Related]
2. Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma.
Maitituoheti M; Keung EZ; Tang M; Yan L; Alam H; Han G; Singh AK; Raman AT; Terranova C; Sarkar S; Orouji E; Amin SB; Sharma S; Williams M; Samant NS; Dhamdhere M; Zheng N; Shah T; Shah A; Axelrad JB; Anvar NE; Lin YH; Jiang S; Chang EQ; Ingram DR; Wang WL; Lazar A; Lee MG; Muller F; Wang L; Ying H; Rai K
Cell Rep; 2020 Oct; 33(3):108293. PubMed ID: 33086062
[TBL] [Abstract][Full Text] [Related]
3. KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation.
Guo C; Chen LH; Huang Y; Chang CC; Wang P; Pirozzi CJ; Qin X; Bao X; Greer PK; McLendon RE; Yan H; Keir ST; Bigner DD; He Y
Oncotarget; 2013 Nov; 4(11):2144-53. PubMed ID: 24240169
[TBL] [Abstract][Full Text] [Related]
4. MLL4 Is Required to Maintain Broad H3K4me3 Peaks and Super-Enhancers at Tumor Suppressor Genes.
Dhar SS; Zhao D; Lin T; Gu B; Pal K; Wu SJ; Alam H; Lv J; Yun K; Gopalakrishnan V; Flores ER; Northcott PA; Rajaram V; Li W; Shilatifard A; Sillitoe RV; Chen K; Lee MG
Mol Cell; 2018 Jun; 70(5):825-841.e6. PubMed ID: 29861161
[TBL] [Abstract][Full Text] [Related]
5. USP53 promotes apoptosis and inhibits glycolysis in lung adenocarcinoma through FKBP51-AKT1 signaling.
Zhao X; Wu X; Wang H; Yu H; Wang J
Mol Carcinog; 2020 Aug; 59(8):1000-1011. PubMed ID: 32511815
[TBL] [Abstract][Full Text] [Related]
6. Somatic mutations of MLL4/COMPASS induce cytoplasmic localization providing molecular insight into cancer prognosis and treatment.
Zhao Z; Aoi Y; Philips CN; Meghani KA; Gold SR; Yu Y; John LS; Qian J; Zeidner JM; Meeks JJ; Shilatifard A
Proc Natl Acad Sci U S A; 2023 Dec; 120(52):e2310063120. PubMed ID: 38113256
[TBL] [Abstract][Full Text] [Related]
7. Loss of Function of the Gene Encoding the Histone Methyltransferase KMT2D Leads to Deregulation of Mitochondrial Respiration.
Pacelli C; Adipietro I; Malerba N; Squeo GM; Piccoli C; Amoresano A; Pinto G; Pucci P; Lee JE; Ge K; Capitanio N; Merla G
Cells; 2020 Jul; 9(7):. PubMed ID: 32668765
[No Abstract] [Full Text] [Related]
8. KMT2D regulates specific programs in heart development via histone H3 lysine 4 di-methylation.
Ang SY; Uebersohn A; Spencer CI; Huang Y; Lee JE; Ge K; Bruneau BG
Development; 2016 Mar; 143(5):810-21. PubMed ID: 26932671
[TBL] [Abstract][Full Text] [Related]
9. Small Cell Lung Cancer Exhibits Frequent Inactivating Mutations in the Histone Methyltransferase KMT2D/MLL2: CALGB 151111 (Alliance).
Augert A; Zhang Q; Bates B; Cui M; Wang X; Wildey G; Dowlati A; MacPherson D
J Thorac Oncol; 2017 Apr; 12(4):704-713. PubMed ID: 28007623
[TBL] [Abstract][Full Text] [Related]
10. UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells.
Kim JH; Sharma A; Dhar SS; Lee SH; Gu B; Chan CH; Lin HK; Lee MG
Cancer Res; 2014 Mar; 74(6):1705-17. PubMed ID: 24491801
[TBL] [Abstract][Full Text] [Related]
11. Histone H3 lysine 4 methyltransferase KMT2D.
Froimchuk E; Jang Y; Ge K
Gene; 2017 Sep; 627():337-342. PubMed ID: 28669924
[TBL] [Abstract][Full Text] [Related]
12. The low-complexity domains of the KMT2D protein regulate histone monomethylation transcription to facilitate pancreatic cancer progression.
Li W; Wu L; Jia H; Lin Z; Zhong R; Li Y; Jiang C; Liu S; Zhou X; Zhang E
Cell Mol Biol Lett; 2021 Nov; 26(1):45. PubMed ID: 34758724
[TBL] [Abstract][Full Text] [Related]
13. Downregulated METTL14 accumulates BPTF that reinforces super-enhancers and distal lung metastasis via glycolytic reprogramming in renal cell carcinoma.
Zhang C; Chen L; Liu Y; Huang J; Liu A; Xu Y; Shen Y; He H; Xu D
Theranostics; 2021; 11(8):3676-3693. PubMed ID: 33664855
[No Abstract] [Full Text] [Related]
14. DBC1 is a key positive regulator of enhancer epigenomic writers KMT2D and p300.
Kim HJ; Moon SJ; Hong S; Won HH; Kim JH
Nucleic Acids Res; 2022 Aug; 50(14):7873-7888. PubMed ID: 35801925
[TBL] [Abstract][Full Text] [Related]
15. H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.
Lee JE; Wang C; Xu S; Cho YW; Wang L; Feng X; Baldridge A; Sartorelli V; Zhuang L; Peng W; Ge K
Elife; 2013 Dec; 2():e01503. PubMed ID: 24368734
[TBL] [Abstract][Full Text] [Related]
16. Mutant p53 regulates enhancer-associated H3K4 monomethylation through interactions with the methyltransferase MLL4.
Rahnamoun H; Hong J; Sun Z; Lee J; Lu H; Lauberth SM
J Biol Chem; 2018 Aug; 293(34):13234-13246. PubMed ID: 29954944
[TBL] [Abstract][Full Text] [Related]
17. Heterozygous Kmt2d loss diminishes enhancers to render medulloblastoma cells vulnerable to combinatory inhibition of lysine demethylation and oxidative phosphorylation.
Dhar SS; Brown C; Rizvi A; Reed L; Kotla S; Zod C; Abraham J; Abe JI; Rajaram V; Chen K; Lee M
bioRxiv; 2023 Nov; ():. PubMed ID: 37961118
[TBL] [Abstract][Full Text] [Related]
18. Precocious neuronal differentiation and disrupted oxygen responses in Kabuki syndrome.
Carosso GA; Boukas L; Augustin JJ; Nguyen HN; Winer BL; Cannon GH; Robertson JD; Zhang L; Hansen KD; Goff LA; Bjornsson HT
JCI Insight; 2019 Oct; 4(20):. PubMed ID: 31465303
[TBL] [Abstract][Full Text] [Related]
19. The MLL3/4 H3K4 methyltransferase complex in establishing an active enhancer landscape.
Wang LH; Aberin MAE; Wu S; Wang SP
Biochem Soc Trans; 2021 Jun; 49(3):1041-1054. PubMed ID: 34156443
[TBL] [Abstract][Full Text] [Related]
20. KMT2D regulates activation, localization, and integrin expression by T-cells.
Potter SJ; Zhang L; Kotliar M; Wu Y; Schafer C; Stefan K; Boukas L; Qu'd D; Bodamer O; Simpson BN; Barski A; Lindsley AW; Bjornsson HT
Front Immunol; 2024; 15():1341745. PubMed ID: 38765012
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
