BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

265 related articles for article (PubMed ID: 32251410)

  • 1. Discovery of a selective inhibitor of doublecortin like kinase 1.
    Ferguson FM; Nabet B; Raghavan S; Liu Y; Leggett AL; Kuljanin M; Kalekar RL; Yang A; He S; Wang J; Ng RWS; Sulahian R; Li L; Poulin EJ; Huang L; Koren J; Dieguez-Martinez N; Espinosa S; Zeng Z; Corona CR; Vasta JD; Ohi R; Sim T; Kim ND; Harshbarger W; Lizcano JM; Robers MB; Muthaswamy S; Lin CY; Look AT; Haigis KM; Mancias JD; Wolpin BM; Aguirre AJ; Hahn WC; Westover KD; Gray NS
    Nat Chem Biol; 2020 Jun; 16(6):635-643. PubMed ID: 32251410
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural Basis of Inhibition of DCLK1 by Ruxolitinib.
    Jang DM; Lim HJ; Hahn H; Lee Y; Kim HK; Kim HS
    Int J Mol Sci; 2021 Aug; 22(16):. PubMed ID: 34445192
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1.
    Weygant N; Qu D; Berry WL; May R; Chandrakesan P; Owen DB; Sureban SM; Ali N; Janknecht R; Houchen CW
    Mol Cancer; 2014 May; 13():103. PubMed ID: 24885928
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Histone Demethylase KDM3A, Increased in Human Pancreatic Tumors, Regulates Expression of DCLK1 and Promotes Tumorigenesis in Mice.
    Dandawate P; Ghosh C; Palaniyandi K; Paul S; Rawal S; Pradhan R; Sayed AAA; Choudhury S; Standing D; Subramaniam D; Padhye SB; Gunewardena S; Thomas SM; Neil MO; Tawfik O; Welch DR; Jensen RA; Maliski S; Weir S; Iwakuma T; Anant S; Dhar A
    Gastroenterology; 2019 Dec; 157(6):1646-1659.e11. PubMed ID: 31442435
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Doublecortin-Like Kinase 1 (DCLK1) Regulates B Cell-Specific Moloney Murine Leukemia Virus Insertion Site 1 (Bmi-1) and is Associated with Metastasis and Prognosis in Pancreatic Cancer.
    Li J; Wang Y; Ge J; Li W; Yin L; Zhao Z; Liu S; Qin H; Yang J; Wang L; Ni B; Liu Y; Wang H
    Cell Physiol Biochem; 2018; 51(1):262-277. PubMed ID: 30453285
    [TBL] [Abstract][Full Text] [Related]  

  • 6. XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism.
    Sureban SM; May R; Weygant N; Qu D; Chandrakesan P; Bannerman-Menson E; Ali N; Pantazis P; Westphalen CB; Wang TC; Houchen CW
    Cancer Lett; 2014 Aug; 351(1):151-61. PubMed ID: 24880079
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Doublecortin-like kinase 1 is elevated serologically in pancreatic ductal adenocarcinoma and widely expressed on circulating tumor cells.
    Qu D; Johnson J; Chandrakesan P; Weygant N; May R; Aiello N; Rhim A; Zhao L; Zheng W; Lightfoot S; Pant S; Irvan J; Postier R; Hocker J; Hanas JS; Ali N; Sureban SM; An G; Schlosser MJ; Stanger B; Houchen CW
    PLoS One; 2015; 10(2):e0118933. PubMed ID: 25723399
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design and synthesis of doublecortin-like kinase 1 inhibitors and their bioactivity evaluation.
    Pan P; Ji D; Li Z; Meng X
    J Enzyme Inhib Med Chem; 2024 Dec; 39(1):2287990. PubMed ID: 38062554
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biochemical and Structural Insights into Doublecortin-like Kinase Domain 1.
    Patel O; Dai W; Mentzel M; Griffin MD; Serindoux J; Gay Y; Fischer S; Sterle S; Kropp A; Burns CJ; Ernst M; Buchert M; Lucet IS
    Structure; 2016 Sep; 24(9):1550-61. PubMed ID: 27545623
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and Structure-Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6
    Ferguson FM; Liu Y; Harshbarger W; Huang L; Wang J; Deng X; Capuzzi SJ; Muratov EN; Tropsha A; Muthuswamy S; Westover KD; Gray NS
    J Med Chem; 2020 Jul; 63(14):7817-7826. PubMed ID: 32530623
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Doublecortin and CaM kinase-like-1 as an independent prognostic factor in patients with resected pancreatic carcinoma.
    Nishio K; Kimura K; Amano R; Nakata B; Yamazoe S; Ohira G; Miura K; Kametani N; Tanaka H; Muguruma K; Hirakawa K; Ohira M
    World J Gastroenterol; 2017 Aug; 23(31):5764-5772. PubMed ID: 28883702
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing.
    Liu Y; Ferguson FM; Li L; Kuljanin M; Mills CE; Subramanian K; Harshbarger W; Gondi S; Wang J; Sorger PK; Mancias JD; Gray NS; Westover KD
    Cell Chem Biol; 2020 Oct; 27(10):1229-1240.e4. PubMed ID: 32755567
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MicroRNA-195 Suppresses the Progression of Pancreatic Cancer by Targeting DCLK1.
    Zhou B; Sun C; Hu X; Zhan H; Zou H; Feng Y; Qiu F; Zhang S; Wu L; Zhang B
    Cell Physiol Biochem; 2017; 44(5):1867-1881. PubMed ID: 29224010
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DCLK1-Isoform2 Alternative Splice Variant Promotes Pancreatic Tumor Immunosuppressive M2-Macrophage Polarization.
    Chandrakesan P; Panneerselvam J; May R; Weygant N; Qu D; Berry WR; Pitts K; Stanger BZ; Rao CV; Bronze MS; Houchen CW
    Mol Cancer Ther; 2020 Jul; 19(7):1539-1549. PubMed ID: 32371580
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Immune Cell Production of Interleukin 17 Induces Stem Cell Features of Pancreatic Intraepithelial Neoplasia Cells.
    Zhang Y; Zoltan M; Riquelme E; Xu H; Sahin I; Castro-Pando S; Montiel MF; Chang K; Jiang Z; Ling J; Gupta S; Horne W; Pruski M; Wang H; Sun SC; Lozano G; Chiao P; Maitra A; Leach SD; Kolls JK; Vilar E; Wang TC; Bailey JM; McAllister F
    Gastroenterology; 2018 Jul; 155(1):210-223.e3. PubMed ID: 29604293
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MicroRNA-424 inhibits cell migration, invasion, and epithelial mesenchymal transition by downregulating doublecortin-like kinase 1 in ovarian clear cell carcinoma.
    Wu X; Ruan Y; Jiang H; Xu C
    Int J Biochem Cell Biol; 2017 Apr; 85():66-74. PubMed ID: 28161486
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of a Selective and Potent Inhibitor of Mitogen-Activated Protein Kinase-Interacting Kinases 1 and 2 (MNK1/2) Utilizing Structure-Based Drug Design.
    Han W; Ding Y; Xu Y; Pfister K; Zhu S; Warne B; Doyle M; Aikawa M; Amiri P; Appleton B; Stuart DD; Fanidi A; Shafer CM
    J Med Chem; 2016 Apr; 59(7):3034-45. PubMed ID: 27002243
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A New Oxadiazole-Based Topsentin Derivative Modulates Cyclin-Dependent Kinase 1 Expression and Exerts Cytotoxic Effects on Pancreatic Cancer Cells.
    Pecoraro C; Parrino B; Cascioferro S; Puerta A; Avan A; Peters GJ; Diana P; Giovannetti E; Carbone D
    Molecules; 2021 Dec; 27(1):. PubMed ID: 35011251
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma.
    Xie Y; Zhu S; Zhong M; Yang M; Sun X; Liu J; Kroemer G; Lotze M; Zeh HJ; Kang R; Tang D
    Gastroenterology; 2017 Nov; 153(5):1429-1443.e5. PubMed ID: 28764929
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pancreatic Neuroendocrine Tumors and EMT Behavior Are Driven by the CSC Marker DCLK1.
    Ikezono Y; Koga H; Akiba J; Abe M; Yoshida T; Wada F; Nakamura T; Iwamoto H; Masuda A; Sakaue T; Yano H; Tsuruta O; Torimura T
    Mol Cancer Res; 2017 Jun; 15(6):744-752. PubMed ID: 28179411
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.